Search Studies
Studying a New Pneumococcal Disease Vaccine Among Healthy Toddlers
Your child is being asked to join this study because they are healthy, between 12 to 15 months old, and have had 3 doses of Prevnar 20®. The study will test a new vaccine to see if it can protect against a germ that causes infections in children. The goal is to check if the vaccine is safe and helps the body make antibodies to fight the germ.
Study Topics
Healthy Volunteers Infectious Diseases Screening and Prevention Children, Infants, Teen Health
Studying Medicines to Help People Breathe Better with COPD
The purpose if this study is to learn more about the medicines Budesonide, Glycopyrronium, and Formoterol Fumarate. We want to see how well the medicines work for preventing chronic obstructive pulmonary disease (COPD) flare-ups.
Study Topics
Testing a Radiation-Based Treatment for Prostate Cancer that has Spread
The purpose of this study is to find out if radiation treatment with Lutetium Lu 177 Dotatate can shrink or slow the growth of prostate cancer. We want to find out if this approach is better or worse than the usual approach.
Study Topics
Learning More About Blood Tests to Determine if a Cancer Patient Will Respond to Treatment
Not all patients treated with immune checkpoint inhibitors respond with tumor shrinkage. Many patients have serious side effects. The purpose of this study is to develop blood tests that can help determine if patients will respond to treatment and develop side effects.
Study Topics
Testing a Study Device for Treatment of Sudden Tear in the Aorta
The purpose of this study is to find out if the study device called AMDS is safe and works well for treating this condition. We want to see if this device can help heal the aorta's walls and reduce the need for surgery.
Study Topics
Finding out if Antiviral Medicine Worked for Babies or Toddlers with Cytomegalovirus Infection
The purpose of this study is to learn more about the treatment with antiviral medicine for babies born with cytomegalovirus. We want to see if antiviral medicine has any impact on hearing, cancer risk, overall growth, or sexual development.
Study Topics
Infectious Diseases Children, Infants, Teen Health Ears, Nose, Throat, Mouth
Treating Uncontrolled Seizures with the Study Drug NRTX-1001
The purpose of this study is to learn more about treating uncontrolled seizures with the study drug NRTX-1001. We want to see how the study drug works and find out what side effects may be caused.
Study Topics
Using the GORE® Device to Treat Heart Lesions
Aortic disease may cause wounds in the blood vessels near the heart. We want to learn more about the safety and how well the study device, GORE® Ascending Stent Graft, treats these wounds.
Study Topics
Learning More About How Gut Micro-organisms Play a Role in Prostate Cancer
The purpose of this study is to find out how the gut micro-organisms may affect prostate cancer that spreads to the bone. In this study, the methods required to study these gut-bone interactions will be developed and tested.
Study Topics
Learning More About Speech Profiles after a Stroke
The purpose of this study is to learn more about speech profiles among stroke survivors and healthy volunteers. Understanding more about speech profiles can help customize treatment.
Study Topics
A Study of Telehealth to Treat Children with Medical Complexity
The purpose of this study is to learn more about using telehealth visits for children with medical complexity. We want to find out if telehealth visits can improve the health of children with chronic health problems.
Study Topics
Collecting Data for Parkinson's Disease Research
The purpose of this study is to gather information on people with Parkinson's disease through a patient registry. The registry will collect genetic information from people with Parkinson's, those at risk, and others without the disease. The registry will help improve understanding and care for Parkinson's disease.
Study Topics
Testing a New Study Device for Severe Blood Flow Problems in Limbs
Some ductal carcinoma in situ (breast cancer) is lower risk than others for turning into invasive cancer. The purpose of this study is to try and figure out which ductal carcinoma in situ is low risk. It's possible low-risk breast cancer can be treated with only hormone therapy pills and avoid surgery.
Study Topics
Testing a New Study Device for Severe Blood Flow Problems in Limbs
The purpose of this study is to collect information about a device called the LimFlow System, which is used to treat this condition. We want to find out how safe and effective this device is.
Study Topics
Treating Focal Onset Epilepsy with Study Drug BHV-7000
The purpose of this study is to find out how well the study drug, BHV-7000, works for treating focal seizures. We also want to learn more about side effects that may be caused by the study drug.
Study Topics
Studying NDI-219216 for Advanced Solid Tumors with MMR deficiency
The purpose of this study is to learn more about a new medicine for advanced solid tumors. Our researchers will see if the medicine is safe and how the body handles it. The study will also look at whether the pill can help slow down or shrink certain advanced cancers.
Study Topics
A Study of Methotrexate in People with Breast, Brain, or Spinal Cord Cancer
Methotrexate is a type of chemotherapy drug. The purpose of this study is to find out how well high-dose Methotrexate works for treating breast cancer that has spread to the membrane that cover the brain and spinal cord. We also want to find out what the side effects of this treatment may be. Methotrexate will be given to study volunteers in the hospital every 2 weeks until there is evidence that the cancer is growing.
Study Topics
Studying Ablative Local Therapy for Colorectal Cancer
The purpose of this study is to learn if adding special tumor treatments, called ablative local therapy, can help people with colorectal cancer that has spread. These treatments may use surgery, radiation, or heat to target all tumor spots. The goal is to see if adding these treatments to usual cancer medicine helps people live longer.
Study Topics
Understanding How Chemotherapy Treatment Before Surgery Impacts Recovery
The purpose of this study is to learn how chemotherapy treatment before surgery affects your body and brain. Some people get chemotherapy before surgery, and some get it after. By looking at changes in health, doctors hope to understand how chemotherapy before surgery helps people feel better and recover faster. We are looking for volunteers who have recently been diagnosed with a gynecological cancer (ovarian, peritoneal, fallopian tube, or endometrial) and are planning to receive chemotherapy treatment followed by surgery afterwards.
Study Topics
A Study of the Drug AZD5492 for Blood Cancer
The purpose of this study to learn more about the study drug AZD5492. We want to see if this study drug is safe and helpful for treating blood cancers that have not gotten better with other treatments. We need volunteers with certain types of blood cancer like B-cell non-Hodgkin's lymphoma or chronic lymphocytic leukemia/small lymphocytic lymphoma. The study team will provide more information.
Study Topics