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Study of Second Look Laparoscopy with Hyperthermic intraperitoneal chemotherapy (HIPEC) in Patients with Ovarian, Fallopian Tube, or Primary Peritoneal Carcinoma
After their first surgery, patients often have a procedure called second look reassessment surgery. This surgery allows doctors to look inside your body and check for signs of cancer. The purpose of this study is to see how well it works to give HIPEC during the second look surgery. HIPEC is a type of chemotherapy inserted directly into your abdomen at the time of surgery. We want to monitor any effects that this has on your health.
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Women's Health Cancer Cancer: Rare Cancers Cancer: Women's Cancer
Study to Learn More About Severe Asthma
The purpose of this study is to learn more about severe asthma. We will compare people with severe asthma to those with milder forms of asthma.
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Treating Prostate Cancer with Omeprazole and Chemotherapy
The purpose of this study is to find out how Omeprazole may help treat prostate cancer. It will be given along with chemotherapy. Researchers believe Omeprazole may help the chemotherapy work.
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Study to Find Out How Well Different Medications Work for Mild-to-Moderate COVID-19
The purpose of this study is to look at how well certain medications treat mild to moderate COVID-19.
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Learning More About How Cells Age in Your Muscle
The purpose of this research is to understand how the cells in your muscle age over time.
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Aging Healthy Volunteers Men's Health Bones, Joints, Muscles
Treating Low-Risk, Early Stage Breast Cancer with Hormonal Therapy
The usual treatment for low-risk breast cancer is radiation and hormonal therapy. The purpose of this study is to find out how well hormonal therapy alone will work. We want to find out if this approach is better or worse than the usual approach.
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Quitting Smoking and Managing Daily Challenges
The purpose of this study is to learn more about the mood, behavior and brains of people who smoke. We want to look at how daily hassles might affect how emotional distress is managed during an attempt to stop smoking. This study does not offer a treatment to stop smoking.
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Healthy Volunteers Substance Use (Alcohol, Illegal Drugs, Tobacco)
Study to Find Out if the Study Drug, LN145, Works Well for Treating Nonsmall Cell Lung Cancer
The purpose of this study is to find out if the study drug, LN145, works well for treating nonsmall cell lung cancer.
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Study of Batoclimab for Treating Active Thyroid Eye Disease
The purpose of this study is to see if batoclimab helps people with active moderate-to-severe thyroid eye disease. We also want to find out if batoclimab is safe.
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Learning More About the Effects of Very Low-Nicotine Cigarettes on the Heart
The purpose of this study is to learn more about the effects of very low-nicotine cigarettes on the heart.
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Heart Health Substance Use (Alcohol, Illegal Drugs, Tobacco)
Study of the Drug GS-8588 in People with HIV-1 Who are Virologically Suppressed on Antiretroviral Therapy
The purpose of this study is to find out how well the study drug GS-8588 is tolerated when given at different doses. We also want to find out how the body's immune system reacts to GS-8588.
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Learning More About Treating Migraine in Children and Young Adults with Rimegepant
The purpose of this study is to learn how well the study drug, Rimegepant, treats migraines in children and young adults. We also want to learn more about the possible side effects of the study drug.
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Improving Memory by Improving Sleep
Sleep is a critical part of long-term memory storage. Aging can cause issues with sleep and memory. The goal of this study is to see if improving sleep can improve memory. Volunteers will wear a headband during sleep that will record brain activity. This headband will also provide low-level electrical stimulation to increase deep sleep. Deep sleep is a stage of sleep that is important for memory.
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Studying a New COVID-19 Vaccine among Patients who have Received a Cell Therapy
The purpose of this study is to see if a new vaccine called GEO-CM04S1can help people who have received a cell therapy build protection from COVID-19. We want to compare this new vaccine to the current COVID-19 vaccines and see which one will work better.
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Finding Out if Inclisiran Can Help Prevent Heart-Related Events Like Heart Attack or Stroke
The purpose of the study is to find out if the study drug, inclisiran, can prevent heart-related events by lowering LDL-cholesterol in the blood. LDL cholesterol is also known as bad cholesterol.
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Treating Inclusion Body Myositis with the Study Drug ABC008
Inclusion body myositis (IBM) is an inflammatory autoimmune disorder of skeletal muscle. With IBM harmful immune cells attack muscle causing muscle weakness. The study drug ABC008 has been designed to reduce the number of these harmful immune cells. The purpose of this study is to find out how well the study drug works for treating IBM.
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Learning More About Treating Large B-cell Lymphoma or Follicular Lymphoma with Additional Treatment
The purpose of this study is to find out if we can lower the chance of your diffuse large B-cell lymphoma growing or spreading by adding treatment to the usual approach. The usual approach is to watch the patient's condition unless symptoms appear or change. We want to know which approach is better.
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Combining the Study Drug, REGN5458, with Other Treatments for Multiple Myeloma
The main purpose of this study is to find out if the study drug, REGN5458, can be given safely with other multiple myeloma treatments. We also want to find out what dose of REGN5458 should be used.
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Looking Into the Need of Blood Thinners as Treatment for Atrial Fibrillation
Blood thinning drugs are usually used to treat atrial fibrillation. Atrial fibrillation is when the heart has an irregular and often very fast heart rhythm. Blood thinners lower the risk of stroke but also increase the risk of bleeding. It may not be necessary for people who have short or infrequent atrial fibrillation to take blood thinners. The purpose of this study is to find out if it is safe to stop blood-thinning medication during long periods of normal heart rhythm.
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Using Dexpramipexole for the Treatment of Severe Eosinophilic Asthma
The purpose of this study is to find out how well the study drug dexpramipexole works for the treatment of severe asthma. We also want to learn more about the safety of the study drug.
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