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Studying Two Ways to Treat Stomach Cancer
The purpose of this study is to learn more about different ways to treat stomach cancer. Our researchers want to see if giving a cancer medicine called paclitaxel directly into the belly, along with regular chemotherapy, can help lower the chance of stomach cancer growing or spreading. We will compare this new treatment to the usual care most people get for stomach cancer.
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Studying Durvalumab for Patients with High-Risk Liver Cancer
The purpose of this study is to learn more about different ways to treat stomach cancer. Our researchers want to see if giving a cancer medicine called paclitaxel directly into the belly, along with regular chemotherapy, can help lower the chance of stomach cancer growing or spreading. We will compare this new treatment to the usual care most people get for stomach cancer.
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Comparing Two Medicines for Brain Cancer
The purpose of this study is to find out which medicine works better for people who have a type of brain cancer called glioblastoma. We will compare the medicine niraparib and temozolomide, along with radiation therapy. The goal is to see which treatment helps more and is safer.
Study Topics
Cancer Cancer: Brain, Nervous System, Spinal Cord Cancer: Rare Cancers
Learning More about a New AML Cancer Treatment
The purpose of this study is to learn more about a cancer medicine called venetoclax. We want to see if adding this medicine to the usual chemotherapy can help treat patients with newly diagnosed myeloid leukemia (AML). We will compare this new treatment to the usual treatment for this type of cancer.
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Testing the Study Drug SNDX-5613 for Patients with Newly Diagnosed Acute Myeloid Leukemia
The purpose of this study is to learn more about the study drug SNDX-5613. We want to see if adding this study drug to the usual treatment can help patients who have just been diagnosed with a type of blood cancer called acute myeloid leukemia. We want to find out how much of the drug will cause serious side effects in patients. This will help doctors find out the best amount of the drug to use in future treatments for this cancer.
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Studying Care Choices After Breast Cancer Surgery
The purpose of this study is to compare two different approaches to care for breast cancer after surgery. Our researchers want to find out whether closely monitoring patients after surgery works just as well as giving additional medication to prevent the cancer from returning. This study is for volunteers who had triple-negative breast cancer and showed no signs of cancer after completing chemotherapy and surgery. The results will help doctors determine the best way to care for patients in this situation.
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Studying Radiation vs Usual Care for Cancer that Spread to Bones
The purpose of this study is to help patients who have cancer that has spread to their bones but is not causing pain yet. We want to find out if giving radiation therapy before symptoms start can help prevent problems from bone cancer. Volunteers in this study will either get the usual care or the usual care plus radiation. The goal is to see which option works better to stop bone problems like fractures or spinal cord issues.
Study Topics
Cancer Cancer: Men's Cancer Cancer: Sarcoma (Bone, Muscle, Soft Tissue) Cancer: Solid Tumor Cancer: Women's Cancer
Studying the Supplement Fisetin to Help Cancer Survivors with Tiredness
The purpose of this study is to learn more about fisetin, a dietary supplement. We want to find out if this supplement can help reduce tiredness in people who have had cancer treatments. We will compare this supplement to a placebo. We are looking for volunteers who previously had cancer treatments that often cause tiredness. The study team will provide more information.
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Studying New Drug Combinations for Advanced Small Cell Lung Cancer
The purpose of this study is to find the highest safe dose of a new drug, iadademstat, when used with other cancer drugs (atezolizumab or durvalumab) in people with advanced small cell lung cancer. The study will check for side effects and see how well the drug combination works. This may help doctors learn if this new treatment is better or worse than the usual care for this cancer.
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Finding the Best Blood Cancer Treatment Using Blood Tests
The purpose of this study is to find out if doctors can quickly test blood and bone marrow to look for signs that help choose the best cancer treatment. These signs, called markers, can show which treatments might work best. If your test shows certain markers, you might be able to join a special treatment group. If not, your doctor will give you the usual care. We are looking for volunteers who have previously untreated acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS).
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Studying a New Treatment Combination for Nasopharyngeal Cancer
The purpose of this study is to learn more about combining a medicine called nivolumab to chemotherapy for people with newly diagnosed nasopharyngeal cancer. Our researchers also want to see if some children can safely receive less radiation based on how well the cancer responds. The goal is to treat the cancer while lowering side effects.
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Studying the Medicine Triptorelin to Protect Ovaries During Chemotherapy
The purpose of this study is to learn more about a medicine called triptorelin. We want to find out if it can help protect the ovaries of teens and young adults during cancer treatment. Some cancer drugs can damage the ovaries and make it harder to have children later in life. Our researchers are studying this medicine to see if it works better than the usual methods used to protect the ovaries. We are looking for women volunteers with cancer who are receiving a specific type of chemotherapy called an alkylating agent.
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Stem Cell Transplant After Chemotherapy for Lymphoma Patients
The purpose of this study is to find out if giving a stem cell transplant after chemotherapy helps people with Peripheral T-cell Lymphoma stay healthy longer. Doctors will compare people who get the transplant to people who do not. The goal is to see which way works better to keep the cancer from coming back.
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Testing Two Different Ways to Help Unblock Stomachs
The purpose of this study is to compare two different treatments to help people with blocked stomachs, usually because of cancer. We want to see which treatment works better and can lower the chance of symptoms like pain, nausea or vomiting from coming back.
Study Topics
Stomach and Intestines Cancer Cancer: Stomach and Intestines
Studying Plixorafenib for Cancers with BRAF Gene Changes
The purpose of this study is to learn more about the medicine plixorafenib. We want to see if this medicine can help people whose cancer has a change in the BRAF gene. The medicine is being studied to see if it works and if it is safe. People in the study will take the medicine and be watched closely for any changes or side effects.
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A Study of the Drug Reparixin for Patients with Myelofibrosis
The purpose of this study is to learn more about the study drug Reparixin. This study drug is for people with a type of blood cancer called myelofibrosis. We want to find out if Reparixin is safe and if it helps treat this cancer.
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Testing the Study Drug Levocarnitine to Prevent Liver Damage in Leukemia or Lymphoma Patients
The purpose of this study to learn more about the study drug Levocarnitine. We want to see if this study drug protects the liver from chemotherapy for leukemia or lymphoma.
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Using the TheraBionic Device to Treat Advanced Pancreatic Cancer
The purpose of this study is to find out how the TheraBionic device will affect pancreatic cancer. The TheraBionic device is a small portable device. We want to see if the device will prevent cancer growth.
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Studying a Blood Test to Guide Cancer Treatment After Surgery
The purpose of this study is to see if a blood test can help doctors decide who needs extra cancer treatment after surgery for bladder, kidney. Ureter, or urethra cancer. The blood test looks for cancer DNA in the blood. If the test finds cancer DNA, patients may get one or two cancer drugs, or they may be watched closely.
Study Topics
Cancer Cancer: Kidney, Liver, Pancreas Cancer: Urinary and Bladder
Studying Pump Chemotherapy For Colorectal Cancer that Spread to the Liver
Hepatic arterial infusion (HAI) chemotherapy is a way to give cancer medicine straight into the liver using a small pump. The purpose of this study is to see if using this type of chemotherapy with regular chemotherapy can help people with colorectal cancer that has spread to the liver. Doctors will compare people who get both treatments to people who get only regular chemotherapy. The goal is to find out which treatment helps patients live longer and feel better.
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