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Comparing Two Different Methods of Surgery to Treat Osteosarcoma that Has Spread to the Lungs
The purpose of this study is to compare two different surgery methods for people with osteosarcoma that has spread to the lung. We want to find out which surgery method is better. One method is called open thoracic surgery. It is done through a single large cut between the ribs, opens the chest, and removes the cancer. The other method is called thoracoscopy. It is done through several small incisions and uses a small camera to help with removing the cancer. Both methods are considered standard treatment.
Study Topics
Adding Naxitamab to the Usual Treatment for Neuroblastoma
The purpose of this study is to find out how well Naxitamab works for treating neuroblastoma. Naxitamab will be given along with the usual treatment.
Study Topics
Cancer Cancer: Brain, Nervous System, Spinal Cord Cancer: Rare Cancers
Study of Second Look Laparoscopy with Hyperthermic intraperitoneal chemotherapy (HIPEC) in Patients with Ovarian, Fallopian Tube, or Primary Peritoneal Carcinoma
After their first surgery, patients often have a procedure called second look reassessment surgery. This surgery allows doctors to look inside your body and check for signs of cancer. The purpose of this study is to see how well it works to give HIPEC during the second look surgery. HIPEC is a type of chemotherapy inserted directly into your abdomen at the time of surgery. We want to monitor any effects that this has on your health.
Study Topics
Women's Health Cancer Cancer: Rare Cancers Cancer: Women's Cancer
Learning More About the Benefits of Chemotherapy Before and After Surgery for Gallbladder Cancer
The usual treatment for gallbladder cancer includes chemotherapy after surgery. We want to find out if it is better to give chemotherapy both before and after surgery. We want to see if this approach is better or worse than the usual approach.
Study Topics
Treating Low-grade Serous Ovarian or Peritoneal Cancer with Letrozole
The purpose of this study is to find out if we can we lower the chance of your ovarian or peritoneal cancer growing or spreading with the study drug Letrozole. We want to find out if this approach is better or worse than the usual approach for treating this type of cancer.
Study Topics
Cancer Cancer: Rare Cancers Cancer: Sarcoma (Bone, Muscle, Soft Tissue) Cancer: Women's Cancer
Is it More Helpful to Give Children with Germ Cell Tumors Chemotherapy on a Faster Schedule
A germ cell tumor is a type of cancer found in the ovaries for females or the testes for males. This tumor may also be found in the pelvis along the tailbone, chest, abdomen, and other structures of the body. Chemotherapy is the medicine used to fight cancer. We want to find out if giving children with germ cell tumors chemotherapy on a faster schedule is effective.
Study Topics
A Study of the Drug Durvalumab for Patients with High-Risk Liver Cancer
The purpose of this study is to learn more about the study drug Durvalumab when combined with classic chemotherapy. We want to find out if this approach is better or worse than the usual approach for your liver cancer.
Study Topics