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Mobile App Support for Young Women with Breast Cancer
The purpose of this study is to look at a new way to better support young women with breast cancer. Our researchers will look at whether a mobile app can provide support and help lower stress. The app lets women connect with others and learn helpful information. This study is for volunteers who have been diagnosed with breast cancer at any stage.
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Studying a New Medicine Combination for Advanced Breast Cancer
The purpose of this study is to learn if a new medicine (GDC‑4198), alone or with another medicine, is safe and works for people with advanced breast cancer. The study will also compare this new treatment to a standard treatment. Researchers want to find the best dose and see how well the treatments help control the cancer. This study is for volunteers with type of breast cancer that is hormone receptor‑positive and HER2‑negative that has spread or cannot be removed by surgery and has already been treated with a CDK4/6 inhibitor.
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Studying the Medicine MK-2870 for Breast Cancer After Surgery
The purpose of this study is to learn more about a new medicine called MK-2870. We want to see if this medicine works better than current treatments for people with triple-negative breast cancer who had surgery but still have cancer. Our researchers want to see which treatment helps people live longer and feel better. They also want to learn about side effects and how safe the new medicine is.
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Studying the Medicine BMS-986482 for Advanced Solid Tumors
The purpose of this study is to learn more about the medicine BMS-986482. We want to see if this medicine is safe and works well for patients with certain types of cancer including non-small cell lung cancer, melanoma, colorectal cancer, breast cancer, urothelial cancer, prostate cancer, head and neck cancer or gastric cancer. We will compare this medicine alone or with other approved cancer medicines.
Study Topics
Cancer Cancer: Breast Cancer: Colon, Rectum, Anus Cancer: Head, Neck Cancer: Lung Cancer: Prostate Cancer: Skin Cancer: Stomach and Intestines Cancer: Urinary and Bladder
Studying a New Cancer Therapy for Advanced Solid Tumors
X-PACT is a new cancer treatment that uses a drug called psoralen and a low dose of X-rays. This study wants to see if this treatment is safe and helpful for patients. Volunteers need to have advanced head and neck cancer, soft tissue sarcoma, breast cancer, melanoma, or other solid tumors that didn't get better with other treatments.
Study Topics
Cancer Cancer: Breast Cancer: Head, Neck Cancer: Sarcoma (Bone, Muscle, Soft Tissue) Cancer: Skin Cancer: Solid Tumor
Studying New Treatments for Advanced Breast Cancer
The purpose of this study is to learn more about a new drug, MK-2870, alone or with another drug called pembrolizumab. We want to see how well they work compared to standard chemotherapy. The goal is to find out which treatment helps people live longer and feel better. This study is for volunteers with advanced breast cancer that cannot be removed by surgery.
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Testing the Study Drug INX-315 for Patients with Advanced Cancer
The purpose of this study is to learn more about the study drug INX-315. We want to see if this study drug is a safe treatment for patients with certain types of advanced cancer or cancer that has spread to other parts of the body. Study team will provide more information on eligibility criteria.
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Testing Cancer Drug Doses for Older Adults with Breast Cancer
The purpose of this study is to test two cancer drugs, palbociclib and ribociclib. We want to find the best dose for older adults with breast cancer. We want to help patients stay on treatment longer with fewer side effects. The study is for volunteers with hormone receptor-positive, HER2-negative breast cancer that has spread to another part of the body.
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Using a Tracker to Learn More about Heart Rate Variability Changes and Cancer-Related Tiredness
This study aims to help people with pancreatic and breast cancer who feel very tired because of their illness. We will use an activity tracker to check changes in your heart rate variability and how well you sleep. We will also ask you to fill out surveys and keep a diary about your tiredness. The information we collect may help us understand how heart rate variability changes are related to cancer-related tiredness. This study will last around 1 month.
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Studying Extra Therapies People Use During Cancer Treatment
The purpose of this study to learn more about other ways people manage their cancer symptoms while they are getting treatment. These other ways include using things like cannabis (also called marijuana), vitamins or supplements, and doing activities like acupuncture or meditation. We want to find out if these methods help or hurt people compared to the usual care they get from their doctor.
Study Topics
Cancer Cancer: Breast Cancer: Colon, Rectum, Anus Cancer: Lung Cancer: Lymphoma Cancer: Skin
Helping Improve Breast Cancer Care for Young Women
The purpose of this study is to learn more about breast cancer in younger women and help improve care in the future. Researchers will collect blood, tissue, and stool samples from women who were diagnosed with breast cancer between the ages of 18 and 45. They will look for patterns and differences to help guide future research and treatment.
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Neurology Disorders Rare Disease Arthritis, Lupus, and Autoimmune Disorders
Mindfulness Programs for Young Breast Cancer Survivors
The purpose of this study is to help young breast cancer survivors who are feeling symptoms of depression. Researchers will test different ways to teach mindfulness to learn which method works best to improve mood and well-being. The programs may be done online, through an app, or with guided meditation. This study is for volunteers who had breast cancer and finished treatment, are feeling symptoms of depression, and were aged 18 to 50 when diagnosed.
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Testing the Drugs Inavolisib and Phesgo for Advanced Breast Cancer Treatment
This study aims to learn about a new drug combination for breast cancer that has spread. We want to compare the side effects of the drugs inavolisib and Phesgo with a placebo and Phesgo. Volunteers must have HER2-positive PICK3CA-mutated breast cancer, study team will provide more details.
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A Study of the Drug OP-1250 for Advanced Breast Cancer Patients
The purpose of this study is to learn about the drug OP-1250 when used with either ribociclib or alpelisib. We want to see if this drug is safe and helpful for patients with advanced breast cancer or breast cancer that has spread, which is hormone receptor-positive and HER2-negative. We also want to find the best dose of this drug.
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Studying Care Choices After Breast Cancer Surgery
The purpose of this study is to compare two different approaches to care for breast cancer after surgery. Our researchers want to find out whether closely monitoring patients after surgery works just as well as giving additional medication to prevent the cancer from returning. This study is for volunteers who had triple-negative breast cancer and showed no signs of cancer after completing chemotherapy and surgery. The results will help doctors determine the best way to care for patients in this situation.
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Studying PF-07248144 for HER2-Negative Breast Cancer
The purpose of this study is to learn more about a new medicine called PF-07248144 used with fulvestrant. Researchers want to see if this medicine can help people with a type of breast cancer called HER2-negative that has grown or spread and got worse after other treatment. Researchers will compare the new treatment to standard treatments to see if it works better and is safe.
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Studying Hair Loss in Women of African Descent during Chemotherapy
The purpose of this study is to understand hair loss in African American women who are getting chemotherapy for breast cancer. We want to find out how common different types of hair loss are with chemotherapy. We also want to learn about the participants' health history, medical information, and hair styling habits.
Study Topics
Minority Health Skin, Hair, Nails Women's Health Cancer Cancer: Breast
Studying Two Treatments for Early Stage Breast Cancer
The purpose of this study is to learn more about adding chemotherapy to hormone treatment for breast cancer. We will compare two common treatments to see which works better. The goal is to find out if adding chemotherapy can prevent the cancer from returning and learn more about the possible side effects. We are looking for volunteers who have early-stage breast cancer, are HER2-negative, and have not gone through menopause yet.
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