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Studying a Type of Blood Test Used to Find Cancer in People With Sarcoma
The purpose of this study is to look at how well a special blood test called LP-WGS can find cancer in people with bone or soft tissue sarcoma (a type of cancer).
Study Topics
Studying a New Cancer Therapy for Advanced Solid Tumors
X-PACT is a new cancer treatment that uses a drug called psoralen and a low dose of X-rays. This study wants to see if this treatment is safe and helpful for patients. Volunteers need to have advanced head and neck cancer, soft tissue sarcoma, breast cancer, melanoma, or other solid tumors that didn't get better with other treatments.
Study Topics
Cancer Cancer: Solid Tumor Cancer: Breast Cancer: Head, Neck Cancer: Sarcoma (Bone, Muscle, Soft Tissue) Cancer: Skin
Testing the Study Drug Cabozantinib for Kids and Teens with Bone Cancer
The purpose of this study is to test the study drug cabozantinib. We want to see if this study drug helps kids and young adults with a type of bone cancer called osteosarcoma. We will compare cabozantinib with standard care to check if it works better and check to see if it safe. We are looking for volunteers with remaining cancer that cannot be removed by surgery after using chemotherapy treatment. The study team will provide more information.
Study Topics
Using NK Cells to Treat Sarcoma
The purpose of this study is to see if adding a special type of immune cell called "natural killer" (NK) cells to chemotherapy can help treat cancer better. NK cells are good at finding and killing cancer cells.
Study Topics
Cancer Cancer: Children, Teens Cancer: Sarcoma (Bone, Muscle, Soft Tissue)
Studying Radiation vs Usual Care for Cancer that Spread to Bones
The purpose of this study is to help patients who have cancer that has spread to their bones but is not causing pain yet. We want to find out if giving radiation therapy before symptoms start can help prevent problems from bone cancer. Volunteers in this study will either get the usual care or the usual care plus radiation. The goal is to see which option works better to stop bone problems like fractures or spinal cord issues.
Study Topics
Cancer Cancer: Men's Cancer Cancer: Sarcoma (Bone, Muscle, Soft Tissue) Cancer: Solid Tumor Cancer: Women's Cancer