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Checking for AL Amyloidosis among Patients with Smoldering Multiple Myeloma
Smoldering Multiple Myeloma is a blood disorder that can become a more serious cancer called multiple myeloma. This study aims to find out if checking for certain genes is connected to the development of AL amyloidosis in people aged 40 or older with this disorder.
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Study of Decreasing Drinking in Heavy Alcohol Users
The purpose of this study is to see how a tool called transcranial magnetic stimulation (TMS) may change the brain's response to alcohol related pictures. TMS is a technique that does not require surgery or anesthesia. The treatment may help reduce alcohol cravings in people with alcohol use disorder.
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Testing Cancer Drug Doses for Older Adults with Breast Cancer
The purpose of this study is to test two cancer drugs, palbociclib and ribociclib. We want to find the best dose for older adults with breast cancer. We want to help patients stay on treatment longer with fewer side effects. The study is for volunteers with hormone receptor-positive, HER2-negative breast cancer that has spread to another part of the body.
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Low Muscle Mass and its Role in Side Effects from Colorectal Cancer Treatment in Older Adults
The purpose of this study is to find out if low muscle mass plays a role in side effects from colorectal cancer treatment.
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Testing the Study Drug XmAb819 for Patients with Kidney Cancer
The purpose of this study is to find out if low muscle mass plays a role in side effects from colorectal cancer treatment.
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Studying the Drug SGR3515 for Patients with Advanced Solid Tumors
The study aims to learn about the drug SGR-3515. We want to see if it is safe and works well for treating advanced solid tumors. We also want to find the best dose and schedule for treating your cancer. We are looking for volunteers with advanced solid tumors who have either stopped benefiting from or cannot tolerate previous treatments, or whose cancer has returned.
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Online Learning Tool to Help People with Migraines
The purpose of this study is to see how well an online learning tool works for people with migraine. We need feedback to help ensure this learning tool is usable for people with migraine.
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Collecting Blood and Tissue Samples from Patients with Blood Cancer (myeloproliferative neoplasms)
The goal of this study is to gather blood and tissue samples from patients with a type of blood cancer (myeloproliferative neoplasms). The samples will be used to help find new approaches to treatment.
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Learning More About a New Treatment for Diabetic Macular Edema
Diabetic macular edema (DME) is the gathering of fluid in the retina area of the eye. The purpose of this study is to see how well the study drug, RO7200220, works for treating DME.
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Studying the Drug MM-1-104 for People with Advanced or Spreading Cancer
The purpose of this study is to test a new drug called IMM-1-104. We want to see if this study drug is safe and useful for people with advanced or spreading cancer. The drug aims to stop cancer growth.
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Learning About Tiredness in Lung Cancer Patients
We want to understand why people with a type of lung cancer feel tired. We also want to know if exercise can help and how caregivers can support patients in staying active. We are looking for volunteers who have a type of lung cancer called non-small cell lung cancer or are caregivers for someone with it. This study will last around 3 months.
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IGROOVE: A Dance and Music Study for Older Adults with Memory Concerns
The purpose of the study is to see how music and dance may affect fitness and brain health. The study will include people who are concerned about their memory but have not been diagnosed with memory loss.
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Testing the Study Drug Nivolumab for Patients with Multiple Myeloma
The goal of this study is to learn more about the study drug nivolumab. We want to find out if this drug is safe and helpful for people with multiple myeloma that has returned and isn't responding to other treatments. People who want to join this study must have already tried another drug called idecabtagene vicleucel.
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Testing Two Treatments for Prostate Cancer
The purpose of this study is to test two treatments for prostate cancer. We will compare Docetaxel alone to Docetaxel plus Radium-223. We want to see which treatment works better for men with advanced prostate cancer that has spread to bones. This study will help doctors find out which treatment helps patients live longer and feel better.
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Treating Head and Neck Cancer with Cetuximab
The purpose of this study is to see how well the drug Cetuximab works for treating head/neck cancer that stopped responding to treatment. It is possible that Cetuximab may work better when given in patients who have already had immunotherapy.
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Studying Opioid Use After Cancer Surgery
The purpose of this study is to see how many pain pills are taken by cancer patients after surgery. We also want to see how patients get rid of leftover pills and how happy they are with their care. We are looking for volunteers who are already scheduled to have surgery to remove their bladder, kidney, or prostate because of cancer at Atrium Health Wake Forest Baptist Comprehensive Cancer Center.
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Cancer Cancer: Kidney, Liver, Pancreas Cancer: Prostate Cancer: Urinary and Bladder
The HEALEY Trial: Learning More About Different Treatments for ALS
The purpose of this study is to learn more about multiple treatments for amyotrophic lateral sclerosis (ALS). We want to find out if different treatments have an effect on ALS. We also want to find out if these treatments are safe to take without causing too many side effects.
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Looking at the Connection Between Endometriosis and Pregnancy Loss
The purpose of this study is to understand why some women repeatedly lose pregnancies. This study will look at tissue and blood samples from women with unexplained recurrent pregnancy loss.
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Testing New Lymphoma Treatment Combinations
The purpose of this study is to test if different drug combinations are safe and work well for treating lymphoma. We want to see how your body processes these drugs and what effects they have on your cancer. We are testing two combinations: mosunetuzumab with CC-220 or CC-99282, and glofitamab with obinutuzumab and CC-99282. We will use different doses and schedules to see what works best.
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Concussion Symptoms in Young People Ages 11-17
The purpose of this study is to learn more about concussion symptoms in young people ages 11 to 17. This may help us develop future treatments.
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