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Comparing Home and Office-Based Care for Black Patients with High Blood Pressure
The purpose of this study is to compare two ways to improve care for non-Hispanic Black patients with high blood pressure. The first way provides care to patients electronically through phone and video visits. The second way is in person, at a doctor's office, the way someone might normally seek care. All patients will receive a cuff to self-monitor their blood pressure at home. We want to see which way would work better.
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Looking at How Estrogen Deprivation Affects Heart Function in Breast Cancer Patients
The purpose of this study is to learn more about how near complete estrogen deprivation therapy effects the heart in breast cancer patients. We want to understand if this therapy changes how the heart works.
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Using a Blood Test to Guide Colon Cancer Treatment
The purpose of this study is to find out if a blood test can help doctors choose the best kind of chemotherapy for people who had surgery for colon cancer. This blood test looks for something called ctDNA. ctDNA is tiny pieces of DNA from cancer cells that can be found in your blood. We want to see if using this blood test is better or worse than the usual way of deciding on treatment. We are looking for volunteers who have colon cancer and have been treated with surgery.
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Using Muscle Fiber Fragment Injections to Treat Fecal Incontinence
The purpose of this study is to look at a new way to treat fecal incontinence. We want to know if injecting muscle fiber fragments into the muscle at the bottom of the anus can help with leaking stool.
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Learning More about Eye Movement among ALS Patients
The purpose of this study is to learn how ALS, a disease that affects nerve cells, changes the way people move their eyes. What the researchers learn from this study could help make better tools for people with ALS. We also hope to help doctors track the disease more easily and learn more about how ALS develops. The researchers plan to share what they find so it can help people living with ALS, their caregivers, and other scientists.
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Can Physical Activity Be Helpful for Lymphoma Patients During Treatment?
The purpose of this study is to find out if exercise or educational classes can be helpful for lymphoma patients. We want to know if exercise or classes can help patients keep their quality of life and ability to exercise. We also want to know if exercise or classes can help lymphoma patients with memory and heart health.
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Using Stereotactic Body Radiation Therapy to Treat Lung Cancer
The purpose of this study is to compare the usual treatment alone to using an additional treatment called Stereotactic Body Radiation Therapy plus the usual treatment.
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Using a Tracker to Learn More about Heart Rate Variability Changes and Cancer-Related Tiredness
This study aims to help people with pancreatic and breast cancer who feel very tired because of their illness. We will use an activity tracker to check changes in your heart rate variability and how well you sleep. We will also ask you to fill out surveys and keep a diary about your tiredness. The information we collect may help us understand how heart rate variability changes are related to cancer-related tiredness. This study will last around 1 month.
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Comparing Different Heart Procedures for Clogged Arteries
Multivessel coronary artery disease is a disease that causes blockages in the blood vessels supplying the heart muscle. The purpose of this study is to compare two common heart procedures to see which one works better for this disease. One uses a small tube and balloon to open clogged heart arteries. The other is surgery to go around the clogged parts. The goal is to see which one helps people live longer and feel better.
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Study to See How Well the Study Drug EPX-100 Works for Treating Dravet Syndrome
The purpose of this study is to see how well the study drug, EPX-100, works for treating Dravet syndrome. We also want to learn more about possible side effects.
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Studying New Ways to Reduce Caregiver Stress
The purpose of this study is to see if listening to nature sounds and using a new technology called CR can help people who take care of loved ones feel less stressed. Taking care of someone can be stressful and affect your health. This study will test if CR can help reduce stress symptoms like anxiety, trouble sleeping, and changes in heart rate in a small group of people.
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Healthy Volunteers Mental Health Neurology Disorders Sleep Brain and Memory
Studying Extra Therapies People Use During Cancer Treatment
The purpose of this study to learn more about other ways people manage their cancer symptoms while they are getting treatment. These other ways include using things like cannabis (also called marijuana), vitamins or supplements, and doing activities like acupuncture or meditation. We want to find out if these methods help or hurt people compared to the usual care they get from their doctor.
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Cancer Cancer: Breast Cancer: Colon, Rectum, Anus Cancer: Lung Cancer: Lymphoma Cancer: Skin
Treating Prostate Cancer with Omeprazole and Chemotherapy
The purpose of this study is to find out how Omeprazole may help treat prostate cancer. It will be given along with chemotherapy. Researchers believe Omeprazole may help the chemotherapy work.
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Studying Digoxin to Help Treat Brain Cancer
The purpose of this study is to learn more about a medicine called digoxin. We want to see if this medicine can help stop a type of brain cancer called medulloblastoma from getting worse. The goal is to learn if this treatment can help and to understand any side effects it may cause. We are looking for volunteers who have been diagnosed with medulloblastoma.
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Cancer Cancer: Brain, Nervous System, Spinal Cord Cancer: Rare Cancers Children, Infants, Teen Health
Quitting Smoking and Managing Daily Challenges
The purpose of this study is to learn more about the mood, behavior and brains of people who smoke. We want to look at how daily hassles might affect how emotional distress is managed during an attempt to stop smoking. This study does not offer a treatment to stop smoking.
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Healthy Volunteers Substance Use (Alcohol, Illegal Drugs, Tobacco)
Testing the Study Drug Olvi-Vec for Ovarian Cancer that Resists Treatment
The purpose of this study is to learn about the drug Olvi-Vec. We want to see if it is safe and helpful for treating ovarian, fallopian tube, or peritoneal cancer that did not get better with a type of treatment called platinum-based chemotherapy.
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Improving Memory by Improving Sleep
Sleep is a critical part of long-term memory storage. Aging can cause issues with sleep and memory. The goal of this study is to see if improving sleep can improve memory. Volunteers will wear a headband during sleep that will record brain activity. This headband will also provide low-level electrical stimulation to increase deep sleep. Deep sleep is a stage of sleep that is important for memory.
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Collecting Samples to Learn About Childhood Cancer
The purpose of this study is to find better treatments in the future for children with cancer. We want to create a large collection of blood and tissue samples from children cancer to help doctors learn more about how cancer and the immune system work together. Information from this study may help us find better ways to treat cancer in the future. We are looking for volunteers who have been diagnosed with any type of pediatric cancer and are under the care of a doctor at Atrium Health.
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Studying a New COVID-19 Vaccine among Patients who have Received a Cell Therapy
The purpose of this study is to see if a new vaccine called GEO-CM04S1can help people who have received a cell therapy build protection from COVID-19. We want to compare this new vaccine to the current COVID-19 vaccines and see which one will work better.
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Using NK Cells to Treat Sarcoma
The purpose of this study is to see if adding a special type of immune cell called "natural killer" (NK) cells to chemotherapy can help treat cancer better. NK cells are good at finding and killing cancer cells.
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Cancer Cancer: Children, Teens Cancer: Sarcoma (Bone, Muscle, Soft Tissue)