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Comparing Two Different Treatment Schedules for Treating Advanced Head and Neck Cancer
The purpose of this study is to learn more about giving the chemotherapy drug, Cisplatin, on a weekly schedule with radiation. We want to see if there are less side effects when given weekly. We also want to find out if weekly Cisplatin can extend your life.
Study Topics
Study of Non-Invasive Therapy for Female Patients with Interstitial Cystitis/Bladder Pain Syndrome
The purpose of this study is to see how well a non-invasive therapy works to treat interstitial cystitis/bladder pain syndrome. The therapy uses a device that sends magnetic waves into the body which may help the body better heal itself. We want to find out if the study therapy can reduce pelvic pain and urinary symptoms.
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Xeomin Injection for Stroke Recovery
The purpose of this study is to learn more about how the study drug, Xeomin, affects walking and balance after a stroke. We will use special devices to measure your movements. The study requires two visits to Carolinas Rehabilitation.
Study Topics
Learning More About Treating Systemic Lupus Erythematosus with Litifilimab
The purpose of this study is to find out if the study drug, Litifilimab, can improve symptoms of lupus. We want to see if the study drug can reduce disease activity and inflammation
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Treating Multiple Myeloma with a Combination of Talquetamab and Teclistamab
The purpose of this study is to learn more about how well the study drugs, talquetamab and teclistamab, work for treating multiple myeloma that has returned or been difficult treat. We also want to find out how well the study drugs work for treating extramedullary disease that has gotten worse after treatment. Extramedullary disease is tumor growth outside of the bone or bone marrow.
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Learning More About Using Sparsentan to Treat Glomerular Disease in Children
The purpose of this study is to find out how well the study drug, Sparsentan, works for treating kidney diseases in children. We also want to learn more about side effects that may be caused by the study drug.
Study Topics
Learning More about COVID-19 Testing and Pandemic Response among Black and African American Communities
The purpose of this study is to learn more about what makes it easier or harder for African Americans to engage in COVID-19 testing and pandemic response. We want to gather information that will lead to better health for everyone.
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Study to See How Well the Study Drug EPX-100 Works for Treating Dravet Syndrome
The purpose of this study is to see how well the study drug, EPX-100, works for treating Dravet syndrome. We also want to learn more about possible side effects.
Study Topics
Testing a Study Device for Treatment of Sudden Tear in the Aorta
The purpose of this study is to find out if the study device called AMDS is safe and works well for treating this condition. We want to see if this device can help heal the aorta's walls and reduce the need for surgery.
Study Topics
Finding Ways to Improve Health for Older Adults with B-cell Non-Hodgkin Lymphoma or Multiple Myeloma
The purpose of this study is to see if we can decrease CAR-T therapy side effects. We also want to see if we can improve care in older adults with non-Hodgkin lymphoma or multiple myeloma. Pre-treatment assessments will be done to identify weaknesses and guide referrals for additional care if needed. We want to see if this approach will improve health for patients.
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Can Listening to Specific Tones Help Decrease Stress in Dementia Caregivers
The purpose of this research study is to find out if six sessions of listening to specific tones can reduce some symptoms of stress.
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Healthy Volunteers Mental Health Neurology Disorders Brain and Memory
Studying the EXCOR® Active Driving Unit for Children in Need of a Device to Help their Heart Pump Blood
The purpose of this study is to learn more about the EXCOR® Active Driving Unit, which is a study device used with the EXCOR®. We want to test the safety and benefit of this study device among children with a heart that is having trouble pumping and supplying blood to the rest of the body and is in need of a device to assist the pumping of the heart.
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Learning More About Treating Type 2 Diabetes with BMF-219
The purpose of this study is to see how well the study drug, BMF-219, works for treating type 2 diabetes. We also want to learn more about any possible side effects.
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Comparing Two Study Drugs for Treatment of Vasculitis
Eosinophilic Granulomatosis with Polyangiitis is a disease that makes small blood vessels swell up in people with asthma. We want to see how two different study drugs, depemokimab and mepolizumab, work to treat this disease. We also want to learn about the possible side effects of each study drug.
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Learning More About Treating Low-Grade Glioma with Vinblastine and Selumetinib
The purpose of this study is to learn more about treating low-grade gliomas. We want to find the highest dose of Vinblastine that can be given safely along with Selumetinib. We also want to find out if Selumetinib and Vinblastine combined work better than Selumetinib alone. Studies like this can help improve treatment and quality of life.
Study Topics
Cancer Cancer: Brain, Nervous System, Spinal Cord Children, Infants, Teen Health
Learning More About Treating Erythropoietic Protoporphyria with Bitopertin
Erythropoietic protoporphyria (EPP) causes painful reactions when skin exposed to light and is associated with liver disease. The purpose of the study is to find out how well the study drug, bitopertin, works for treating EPP. We also want to see what side effects may be caused by the study drug.
Study Topics
Using Blood Flow Imaging to Find Brain Clot Removal Candidates
The purpose of this study is to find out if special brain scans can help find stroke patients who will benefit from a procedure to remove blood clots. You are invited to join this study because you are having a stroke caused by a blood clot blocking blood flow to your brain.
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Learning More About Transthyretin Familial Amyloid Polyneuropathy
Transthyretin familial amyloid polyneuropathy (TTR?FAP) is a rare disorder some people are born with. It affects nerves and organs and can cause numbness in the legs and numbness or pain in the hands. It can also cause stomach, heart, urinary or sexual problems. The purpose of the study is to find out how common TTR-FAP may be. We also want to learn more about the symptoms.
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A Study of the Drug AAV2-hAQP1 for Treating Dry Mouth Among Head and Neck Cancer Patients
The purpose of this study is to learn more about the study drug called AAV2-hAQP1. We want to see if this study drug can help people who have dry mouth because of radiation treatment for head and neck cancer. We want to check if this study drug will increase saliva and see if it is safe and easy for people to use.
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New Test to Diagnosis Mycosis Fungoides
Mycosis Fungoides (MF) is a disease that affects the skin. The purpose of this study is to develop a new test to help diagnose MF.
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