Search Studies
Studying the Medicine BMX-001 to Reduce Mouth Sores in Head and Neck Cancer
The purpose of this study is to learn more about the medicine BMX-00. We want to see if adding this medicine to usual chemotherapy and radiation can help lower the chance or severity of mouth sores and pain in people with head and neck cancer. People in the study will get either BMX-001 or a placebo, along with their regular treatment. The goal is to see if BMX-001 works better than the usual care for these side effects.
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Helping Women Lower Their Risk for HIV
The purpose of this study is to learn more about a program called SHE CARES, which is created to help women reduce their risk of getting HIV. This program is for women who have used stimulants such as methamphetamine (meth) or cocaine by injection in the last 6 months. The goal is to create a supportive program that helps women stay healthy.
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Screening and Prevention Substance Use (Alcohol, Illegal Drugs, Tobacco) Women's Health
Studying Genes and Weight Loss in Patients with Pancreatic Cancer
The purpose of this study is to understand how genes are related to weight loss in people with pancreatic cancer. Weight loss is a common issue for those with pancreatic cancer and can make life more difficult and treatments less useful. We hope to learn how to better treat and help future patients. We are seeking volunteers who have pancreatic cancer that has spread and cannot be removed by surgery.
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Understanding Cancer Fatigue in Survivors
Cancer-related tiredness is a common issue for people who have cancer or have been treated for it. This study aims to understand how cancer survivors and their doctors discuss this tiredness. We want to make a useful poster for exam rooms to improve talking about, diagnosing, and treating this tiredness. We are seeking cancer survivor volunteers who have had at least 1 visit with the Supportive Oncology team at Levine Cancer Institute or the Charlotte or Winston-Salem campus of Atrium Health Wake Forest Baptist Comprehensive Cancer Center. This study will last around 6 months.
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Testing New CAR T-Cell Therapy for Lymphoma
The purpose of this study is to learn more about the study drug, named PMB-CT01, also known as BAFFR-CAR T cells. We want to see if this study drug is safe and useful to treat people with B-cell Non-Hodgkin Lymphomas.
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Testing New Melanoma Treatments
The purpose of this study is to test two new drugs, fianlimab and cemiplimab, for patients with melanoma that can't be removed or has spread. We want to compare these drugs to another treatment called Opdualag. The goal is to see how safe and effective the new drugs are.
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Testing the Study Drug Cabozantinib for Kids and Teens with Bone Cancer
The purpose of this study is to test the study drug cabozantinib. We want to see if this study drug helps kids and young adults with a type of bone cancer called osteosarcoma. We will compare cabozantinib with standard care to check if it works better and check to see if it safe. We are looking for volunteers with remaining cancer that cannot be removed by surgery after using chemotherapy treatment. The study team will provide more information.
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Testing the Study Drug AJ1-11095 for Patients with Myelofibrosis
The goal of this study is to learn more about a drug called AJ1-11095. We want to find out if this drug is safe and helpful for people with a blood and bone marrow disease called myelofibrosis. To join the study, you must have already taken a medicine called a type I JAK2 inhibitor, but still have a big spleen and symptoms from myelofibrosis.
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Testing the Study Drug ABBV-383 for Patients with Multiple Myeloma
The goal of this study is to learn more about the drug ABBV-383. We want to find out if this drug is safe, helpful, and easy to handle when given to adults whose multiple myeloma has returned or didn't improve.
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Checking for AL Amyloidosis among Patients with Smoldering Multiple Myeloma
Smoldering Multiple Myeloma is a blood disorder that can become a more serious cancer called multiple myeloma. This study aims to find out if checking for certain genes is connected to the development of AL amyloidosis in people aged 40 or older with this disorder.
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Testing Cancer Drug Doses for Older Adults with Breast Cancer
The purpose of this study is to test two cancer drugs, palbociclib and ribociclib. We want to find the best dose for older adults with breast cancer. We want to help patients stay on treatment longer with fewer side effects. The study is for volunteers with hormone receptor-positive, HER2-negative breast cancer that has spread to another part of the body.
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Testing the Study Drug XmAb819 for Patients with Kidney Cancer
The purpose of this study is to test a new drug called XmAb819. We want to see if this study drug is safe and works well for volunteers with clear cell renal cell carcinoma that has come back or not responded to other treatments.
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Studying the Drug SGR3515 for Patients with Advanced Solid Tumors
The study aims to learn about the drug SGR-3515. We want to see if it is safe and works well for treating advanced solid tumors. We also want to find the best dose and schedule for treating your cancer. We are looking for volunteers with advanced solid tumors who have either stopped benefiting from or cannot tolerate previous treatments, or whose cancer has returned.
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Learning About Tiredness in Lung Cancer Patients
We want to understand why people with a type of lung cancer feel tired. We also want to know if exercise can help and how caregivers can support patients in staying active. We are looking for volunteers who have a type of lung cancer called non-small cell lung cancer or are caregivers for someone with it. This study will last around 3 months.
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Studying Opioid Use After Cancer Surgery
The purpose of this study is to see how many pain pills are taken by cancer patients after surgery. We also want to see how patients get rid of leftover pills and how happy they are with their care. We are looking for volunteers who are already scheduled to have surgery to remove their bladder, kidney, or prostate because of cancer at Atrium Health Wake Forest Baptist Comprehensive Cancer Center.
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Cancer Cancer: Kidney, Liver, Pancreas Cancer: Prostate Cancer: Urinary and Bladder
Comparing Different Treatments for Patients with Blood Cancer
The purpose of this study is to test two drug combinations for people with a type of blood cancer called Waldenström's Macroglobulinemia or Lymphoplasmacytic Lymphoma. We want to see if the new drug combination is safe and helps fight the cancer. The study is for volunteers who have not been treated for this cancer before.
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Studying a New Biomarker to Predict Breast Cancer Return
The goal of this study is to learn more about a new test called Oncodetect™. This test looks for signs of breast cancer in the blood. We want to see how well this test can find cancer coming back during and after treatments like surgery or radiation.
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Testing the Study Drug Xaluritamig for Prostate Cancer Patients
The purpose of this study is to learn more about the study drug Xaluritamig. We want to see if this study drug is safe and useful to treat patients with prostate cancer that has come back after their main treatment.
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Studying Factors for Successful Knee Injury Recovery in Athletes
The purpose of this research study is to find out what helps our patients recover well after a knee ligament injury and surgery. We are looking for healthy volunteers who participate in organized sports, have not hurt their knees before, and have not had surgery on their spine, hip, knee, ankle, or foot. If you volunteer for this study, you will need to come for a single visit lasting about 2 hours. We will contact you for up to 2 years to see if you get any injuries. This study will help researchers learn new information that may help others in the future.
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