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Learning More About Adding TRC102 to the Usual Non-Small Cell Lung Cancer Treatment
The purpose of this study is to learn more about the study drug, TRC102. We want to see how it can affect Stage III lung cancer. TRC102 will be added to the usual treatment. The addition of TRC102 to the usual treatment could stabilize your cancer and lengthen the time you can live. This study will help the us find out if this approach is better than the usual approach.
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Treating Multiple Myeloma with Study Drug ABBV-383
The purpose of this study is to see how the study drug, ABBV-383, affects patients with multiple myeloma that has returned or been difficult to treat. Some volunteers will get increasing doses of the study drug. We want to see if the increasing doses can reduce a side effect known as cytokine release syndrome.
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Study of Quick Start Durvalumab for Treating Stage III Non-Small Cell Lung Cancer
Durvalumab is usually started 30 days or more after radiation treatment. The purpose of this study is to find out if it is possible to start Durvalumab within 14 days after radiation treatment. We want to see how the quick start affects you and your cancer.
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Testing the Combination of Abemaciclib and Olaparib for Treatment of Ovarian Cancer
The purpose of this study is to learn more about using abemaciclib and olaparib to treat ovarian cancer that has returned. This study tests different doses of the drugs to find the highest dose that is safe and well tolerated. We also want to see what side effects may occur.
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Comparing Single Dose to Multiple Doses of Radiation for Patients with Cancer that Has Spread to the Brain
The purpose of this study is to find out if there are less side effects when radiation therapy is given to small areas of brain cancer over several days compared to one day. We want to find out if this approach is better or worse than the usual approach.
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Comparing Two Surgical Procedures to Reduce the Risk of Ovarian Cancer
The purpose of this study is to compare two different surgeries to reduce the risk of ovarian cancer. The study will look at the process used to decide which surgery is best for the patient. It will also look at symptoms that occur after removal of the ovaries.
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Study of Memory Loss in the African-American Population
The purpose of this study is to better understand what causes memory loss in African Americans. We hope this type of research will result in improved diagnosis, better treatment and possibly prevention.
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Collecting Data from Study Volunteers with Pulmonary Fibrosis and Fibrosing Interstitial Lung Disease
The purpose of this registry is to collect data to be used for future research on pulmonary fibrosis and other conditions that cause scarring in the lungs. This is not a treatment study. We will collect information from you through interviews, questionnaires, and medical records. Blood draw will be required around every six months. Your information will be collected for at least 3 years.
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Learning More About the Medicine XEN1101 for Treating Seizures
The purpose of this study is to find out if the study medicine, XEN1101, can safely reduce seizures.
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Causes of Obesity and Weight Loss
The purpose of this study is to gather data to help learn more about the causes of obesity. We also want to learn more about the things that can affect weight loss.
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How Brain Activity Relates to Your Ability to Shift Attention in Response to Images
The purpose of this study is to look at how brain activity is related to your ability to shift attention when visual cues change. You will be asked to view specified images while receiving an MRI scan.
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Comparing the Drugs Aspirin and Apixaban to See How Well They Work at Preventing Stroke or Death
The purpose of this study is to look at the how the drugs apixaban and aspirin effect patients with irregular heartbeat and recent brain bleeding. We also want to find out which is better at preventing future strokes and death.
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Factors in Early Adulthood that May Lead to Future Lung Disease
The purpose of this study is to find out why some people develop lung disease and others do not. The study will measure your lung health now and continue to collect data from you until the end of the study.
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Finding Better Ways to Diagnose, Treat and Prevent Cancer in Children
The purpose of creating the database is to help find better ways to diagnose, treat and prevent cancer in children.
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Understanding How to Best Care for Patients in the Brain Tumor Clinic
This study will collect information from patients seen in the Brain Tumor Clinic at Wake Forest Baptist Comprehensive Cancer Center. The database will include the patient's symptoms, condition and response to treatment. The data will be used to understand how we can best care for patients seen in our clinic.
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BE WELL with Migraine
The purpose of this study is to test a non-drug, virtual treatment designed to help improve the lives of people with migraine.
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Creating a Database to Learn More About Vercise Deep Brain Stimulation in Patients with Parkinsons Disease
Parkinson's disease affects nerve cells and causes tremors and muscle stiffness. It can also cause difficulty with speech and walking. The purpose of this study is to find out how brain stimulation effects patients with Parkinson's disease.
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Learning More About Duchenne Muscular Dystrophy Patients and Their Treatment
The purpose of this study is to get a better understanding of patients with Duchenne muscular dystrophy who were treated with Eteplirsen, Golodirsen, or Casimersen. We want to learn more about how well those medications worked for treating Duchenne muscular dystrophy.
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How Salt Affects Blood Pressure in Young Adults Who Were Born Prematurely
The purpose of this study is to learn about how salt in the diet affects blood pressure in young adults who were born prematurely. We also want to find out if the medication, allopurinol, can change how salt in the diet affects blood pressure.
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Healthy Volunteers Heart Health Kidneys, Liver, Pancreas Children, Infants, Teen Health
A Study of the Drug ABBV-383 for Patients with AL Amyloidosis
The purpose of this study is to learn more about the study drug ABBV-383 in patients with amyloidosis. We want to find the best dose and learn about the safety and effects of the study drug.
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