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Studying the Medicine Apitegromab for Babies with Muscle Weakness
Spinal muscular atrophy is a disease that makes muscles weak and hard to move. The purpose of this study is to test a new medicine called apitegromab. We want to see if it is safe and helpful for babies under 2 years old who still have trouble moving even though they already got another treatment called survival motor neuron therapy.
Study Topics
Genetic Disorders Movement Disorder Neurology Disorders Rare Disease Bones, Joints, Muscles Children, Infants, Teen Health
Learning More about Eye Movement among ALS Patients
The purpose of this study is to learn how ALS, a disease that affects nerve cells, changes the way people move their eyes. What the researchers learn from this study could help make better tools for people with ALS. We also hope to help doctors track the disease more easily and learn more about how ALS develops. The researchers plan to share what they find so it can help people living with ALS, their caregivers, and other scientists.
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How the Brain Makes Decisions in Patients with Parkinson's Disease
The purpose of this study is to look at how the brain responds to information when it comes to decision making.
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Studying CereGate Therapy in Patients Diagnosed with Parkinson's Disease
The purpose of this study is to learn more about a new therapy called CereGate. We want to see if this type of therapy can reduce freezing movements in patients with Parkinson's Disease.
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The HEALEY Trial: Learning More About Different Treatments for ALS
The purpose of this study is to learn more about multiple treatments for amyotrophic lateral sclerosis (ALS). We want to find out if different treatments have an effect on ALS. We also want to find out if these treatments are safe to take without causing too many side effects.
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Creating a Database to Learn More About Vercise Deep Brain Stimulation in Patients with Parkinsons Disease
Parkinson's disease affects nerve cells and causes tremors and muscle stiffness. It can also cause difficulty with speech and walking. The purpose of this study is to find out how brain stimulation effects patients with Parkinson's disease.
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Learning More About Duchenne Muscular Dystrophy Patients and Their Treatment
The purpose of this study is to get a better understanding of patients with Duchenne muscular dystrophy who were treated with Eteplirsen, Golodirsen, or Casimersen. We want to learn more about how well those medications worked for treating Duchenne muscular dystrophy.
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Studying the Long-Term Usefulness of a Parkinson's Disease Treatment
The purpose of this study is to see how well the drug ABBV-951 works for people with advanced Parkinson's Disease over a long time. We will look at how the drug affects movement, daily activities, and changes in the disease over three years. We need volunteers who have never taken the drug before or who have used it before. The study team will give more details.
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