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Learning More About How Gut Micro-organisms Play a Role in Prostate Cancer
The purpose of this study is to find out how the gut micro-organisms may affect prostate cancer that spreads to the bone. In this study, the methods required to study these gut-bone interactions will be developed and tested.
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Learning More about the Study Drug Lepodisiran to Reduce Heart Attacks and Stroke
The purpose of this study is to learn more about the study drug lepodisiran. We want to see if the study drug can reduce problems like heart attack or stroke in adults with elevated lipoprotein (a). We also want to learn more about the side effects that may be caused by the study drug.
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A Study of Telehealth to Treat Children with Medical Complexity
The purpose of this study is to learn more about using telehealth visits for children with medical complexity. We want to find out if telehealth visits can improve the health of children with chronic health problems.
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Learning More About Treating Solid Tumors with SGN-EGFRd2
The purpose of this study is to learn more about using telehealth visits for children with medical complexity. We want to find out if telehealth visits can improve the health of children with chronic health problems.
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Learning More About a New Approach to Treating Ductal Carcinoma In Situ
Some ductal carcinoma in situ (breast cancer) is lower risk than others for turning into invasive cancer. The purpose of this study is to try and figure out which ductal carcinoma in situ is low risk. It's possible low-risk breast cancer can be treated with only hormone therapy pills and avoid surgery.
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Learning More About the Use of Frexalimab for Treating Relapsing Multiple Sclerosis
The purpose of this study is to see how well the study drug, frexalimab, works for treating relapsing multiple sclerosis. We also want to learn more about possible side effects of the study drug.
Study Topics
Treating Focal Onset Epilepsy with Study Drug BHV-7000
The purpose of this study is to find out how well the study drug, BHV-7000, works for treating focal seizures. We also want to learn more about side effects that may be caused by the study drug.
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Learning More About Factors that May Affect Correct Inhaler Techniques
The purpose of this study is to learn more about factors that may affect correct technique with hand-held inhalers.
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A Study of Methotrexate in People with Breast, Brain, or Spinal Cord Cancer
Methotrexate is a type of chemotherapy drug. The purpose of this study is to find out how well high-dose Methotrexate works for treating breast cancer that has spread to the membrane that cover the brain and spinal cord. We also want to find out what the side effects of this treatment may be. Methotrexate will be given to study volunteers in the hospital every 2 weeks until there is evidence that the cancer is growing.
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Learning More About Treating Eosinophilic Asthma with Dexpramipexole
The purpose of this study is to find out how well the study drug, dexpramipexole, works for treating eosinophilic asthma. We also want to learn more about side effects that may be caused by the study drug.
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Using Body Fat Images to Assess Health
The purpose of this study is to see if we can use medical images of fat throughout the body to assess your health status.
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Aging Healthy Volunteers Heart Health Weight, Metabolism, Nutrition
Using a Care Manager to Address Health Factors and Manage Pain
The purpose of this study is to see if working with a care manager can help people with long-term pain. We want to see if a care manager can help patients learn pain coping skills and improve their daily lives.
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A Study of the Drug Volrustomig for Head and Neck Cancer Treatment
The study wants to learn about a drug called Volrustomig. It aims to find out if this drug is safe and helpful for people with head and neck cancer that hasn't been taken out and has spread to nearby areas. The drug will be given after patients finish their chemotherapy and radiation treatments.
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Studying a New Way to Prevent Blood Clots During Medical Procedures
The goal of this study is to help people who need medical procedures where their blood goes outside their body, like during dialysis or heart surgery. We want to find a way to stop blood clots during these procedures. This study will help us learn how to prevent clots and make these procedures safer. We are looking for healthy volunteers, both adults and children, who are 17-70 years old and weigh over 110 pounds.
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New Migraine Medicine for Teens
The purpose of this study is to learn more about a new medicine called Rimegepant to help teenagers with chronic migraine. We want to see if this medicine is safe and useful to prevent chronic migraine.
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Study of Two Medicines with Radiation for Adults with Sarcoma of the Arms or Legs
The purpose of this study is to learn more about a new treatment for patients with a type of cancer called sarcoma. We want to see if using two medicines, gemcitabine and docetaxel, along with radiation before surgery, can help stop or slow down the return of this cancer.
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Improving Physical Function in Older Adults with Kidney Disease
The purpose of this study is to find out if two different programs can help older people with serious kidney problems. The first program involves exercise with quick movements 3 times per week for 12 weeks is about exercising quickly with weights, and the second program involves taking classes on how to live a healthy lifestyle once per week for 12 weeks is about living a healthy life. The study wants to see if older people enjoy these programs and if they can be done safely. We are looking for volunteers who live within 20 miles of the Reynolda Campus.
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Improving COPD Care for Cancer Patients
Chronic obstructive pulmonary disease (COPD) is a lung disease that makes it hard to breathe because the airways are swollen and narrow. The purpose of this study is to create a new way to help cancer patients who also have COPD. We want to make their treatment easier and improve their care. Our study will look at how well this new care plan works.
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Studying Hair Loss in Women of African Descent during Chemotherapy
The purpose of this study is to understand hair loss in African American women who are getting chemotherapy for breast cancer. We want to find out how common different types of hair loss are with chemotherapy. We also want to learn about the participants' health history, medical information, and hair styling habits.
Study Topics
Minority Health Skin, Hair, Nails Women's Health Cancer Cancer: Breast
Testing New Ulcerative Colitis Treatment
The purpose of this study is to learn more about a new study drug called Lutikizumab. We want to see if this study drug is safe and works well for treating moderate to severe ulcerative colitis. We will compare this study drug to another drug called Adalimumab.
Study Topics
Arthritis, Lupus, and Autoimmune Disorders Stomach and Intestines