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Learning More about Eye Movement among ALS Patients
The purpose of this study is to learn how ALS, a disease that affects nerve cells, changes the way people move their eyes. What the researchers learn from this study could help make better tools for people with ALS. We also hope to help doctors track the disease more easily and learn more about how ALS develops. The researchers plan to share what they find so it can help people living with ALS, their caregivers, and other scientists.
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Comparing Home and Office-Based Care for Black Patients with High Blood Pressure
The purpose of this study is to compare two ways to improve care for non-Hispanic Black patients with high blood pressure. The first way provides care to patients electronically through phone and video visits. The second way is in person, at a doctor's office, the way someone might normally seek care. All patients will receive a cuff to self-monitor their blood pressure at home. We want to see which way would work better.
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Using Stereotactic Body Radiation Therapy to Treat Lung Cancer
The purpose of this study is to compare the usual treatment alone to using an additional treatment called Stereotactic Body Radiation Therapy plus the usual treatment.
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Using a Tracker to Learn More about Heart Rate Variability Changes and Cancer-Related Tiredness
This study aims to help people with pancreatic and breast cancer who feel very tired because of their illness. We will use an activity tracker to check changes in your heart rate variability and how well you sleep. We will also ask you to fill out surveys and keep a diary about your tiredness. The information we collect may help us understand how heart rate variability changes are related to cancer-related tiredness. This study will last around 1 month.
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Comparing Different Heart Procedures for Clogged Arteries
Multivessel coronary artery disease is a disease that causes blockages in the blood vessels supplying the heart muscle. The purpose of this study is to compare two common heart procedures to see which one works better for this disease. One uses a small tube and balloon to open clogged heart arteries. The other is surgery to go around the clogged parts. The goal is to see which one helps people live longer and feel better.
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Studying Extra Therapies People Use During Cancer Treatment
The purpose of this study to learn more about other ways people manage their cancer symptoms while they are getting treatment. These other ways include using things like cannabis (also called marijuana), vitamins or supplements, and doing activities like acupuncture or meditation. We want to find out if these methods help or hurt people compared to the usual care they get from their doctor.
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Cancer Cancer: Breast Cancer: Colon, Rectum, Anus Cancer: Lung Cancer: Lymphoma Cancer: Skin
Studying Digoxin to Help Treat Brain Cancer
The purpose of this study is to learn more about a medicine called digoxin. We want to see if this medicine can help stop a type of brain cancer called medulloblastoma from getting worse. The goal is to learn if this treatment can help and to understand any side effects it may cause. We are looking for volunteers who have been diagnosed with medulloblastoma.
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Cancer Cancer: Brain, Nervous System, Spinal Cord Cancer: Rare Cancers Children, Infants, Teen Health
Testing the Study Drug Olvi-Vec for Ovarian Cancer that Resists Treatment
The purpose of this study is to learn about the drug Olvi-Vec. We want to see if it is safe and helpful for treating ovarian, fallopian tube, or peritoneal cancer that did not get better with a type of treatment called platinum-based chemotherapy.
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Collecting Samples to Learn About Childhood Cancer
The purpose of this study is to find better treatments in the future for children with cancer. We want to create a large collection of blood and tissue samples from children cancer to help doctors learn more about how cancer and the immune system work together. Information from this study may help us find better ways to treat cancer in the future. We are looking for volunteers who have been diagnosed with any type of pediatric cancer and are under the care of a doctor at Atrium Health.
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Studying the Drug SNDX-5613 for Patients with Acute Myeloid Leukemia
The study aims to learn more about the drug SNDX-5613. We want to find the best dose for patients with a blood cancer called acute myeloid leukemia. We also want to see how this drug works when used with two other drugs, daunorubicin and cytarabine.
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Using NK Cells to Treat Sarcoma
The purpose of this study is to see if adding a special type of immune cell called "natural killer" (NK) cells to chemotherapy can help treat cancer better. NK cells are good at finding and killing cancer cells.
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Cancer Cancer: Children, Teens Cancer: Sarcoma (Bone, Muscle, Soft Tissue)
Studying a Medicine for Babies with Alagille Syndrome
The purpose of this study is to learn more about a medicine called Odevixibat for babies with Alagille Syndrome. We want to see if this medicine can safely help reduce itching in babies with this health condition.
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Genetic Disorders Rare Disease Children, Infants, Teen Health
Studying Blood Particles to Help Treat Cancer
The purpose of this study is to learn more about tiny particles in the blood called extracellular vesicles. By studying this, we hope to find out more about different types of cancer and how to treat them better. We will look at the blood samples from patients with similar cancers to see if we can discover new information. This could help doctors choose the best treatments for cancer patients in the future. We are looking for volunteers with urothelial, prostate, or kidney cancer. The study team will provide more information.
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Studying Repotrectinib for Treating Solid Tumors in Children and Young Adults
The purpose of this study is to learn more about a new cancer medication called repotrectinib for children and young adults. We want to see if this medication can safely treat patients with a solid tumor that has spread from the original tumor site to the area around it or to other parts of the body. The study team will provide more information.
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Using Levocarnitine to Protect the Liver During Chemotherapy
The study aims to find out if the study drug, levocarnitine, can reduce severe liver damage caused by chemotherapy in patients with certain cancers.
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Kidneys, Liver, Pancreas Cancer Cancer: Leukemia Cancer: Lymphoma
Studying a New Blood Test for Patients with Blood Cancer
The purpose of this study is to create a new blood test for patients with blood cancer. We want to see if this new blood test can help predict which patients will benefit from a type of immunotherapy called CAR T-cell therapy. We are looking for volunteers with blood cancer that are eligible to receive CAR T-cell therapy. The study team will provide more information.
Study Topics
Cancer Cancer: Blood Cancer: Leukemia Cancer: Lymphoma Cancer: Myeloma
Helping Myeloma Patients Stay Healthy After CAR-T Therapy
The purpose of this study is to learn more about a medicine called iberdomide. We want to see if it is safe to take after a certain cancer treatment called CAR-T. Researchers want to know if this medicine can help keep multiple myeloma from coming back. They also want to see if this new treatment works better than just watching the cancer without giving more medicine.
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Studying a New Medicine for Treating Hepatitis C
The purpose of this study is to learn more about a new medicine called BEM/RZR. We want to see if it works better than another medicine called SOF/VEL for treating hepatitis C. We will also check how the medicine moves through the body and how it changes the amount of hepatitis C in the blood. The goal is to learn how safe and helpful the new medicine is.
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Testing New Treatments for Multiple Myeloma
The purpose of this study is to test a new mix of drugs for people with a type of blood cancer called multiple myeloma. We want to see if adding a new drug, belantamab mafodotin, to the usual treatment of carfilzomib, lenalidomide, and dexamethasone works better. This study will help doctors find out if this new mix helps patients live longer and feel better.
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