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Using a Blood Test to Track Cervical Cancer Treatment Response
The purpose of this study is to learn more about a blood test called circulating tumor DNA (ctDNA) in people with locally advanced cervical cancer. Our researchers want to see how ctDNA levels change during and after chemotherapy and radiation treatment. The goal is to learn if this blood test can help track how well treatment is working.
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Studying Diabetes Medicine for Heart and Kidney Health
The purpose of this study is to learn more about two types of diabetes medicines. We want to see which medicine type helps lower the risk of heart and kidney problems. We are looking for volunteers with type 2 diabetes and a history of heart disease or have high risk for heart disease that are patients of Elizabeth Internal Medicine and Carmel Family Physicians.
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Helping Patients with Cancer Quit Smoking With New Therapy
The purpose of this study is to learn more about a kind of therapy called Dialectical Behavior Therapy Skills Training (DBT-ST). We want to see if this therapy can help people with cancer who smoke to smoke less or quit. We want to find out how it affects their feelings, stress, and how they deal with tough situations. We will also see if people with cancer who smoke would be willing to try this therapy if it were part of their regular care.
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Substance Use (Alcohol, Illegal Drugs, Tobacco) Wellness and Lifestyle Cancer
Studying Injuries From Motor Vehicle and Nonmotorist/Pedestrian Crashes
The purpose of this study is to learn about the causes of injuries in motor vehicle and nonmotorist/pedestrian crashes. We hope that the information we learn from this study will benefit you and others in the future by helping us design and build safer vehicles to prevent injuries and save lives. There will be no change to the care that you are receiving, and your health and vehicle information is protected and will not be disclosed. We are looking for volunteers who have recently been in a motor vehicle or nonmotorist/pedestrian crash with moderate to severe injuries.
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Studying a New Medicine for Multiple Myeloma
The purpose of this study is to learn about the study medicine ABBV-453. We want to see if this medicine is safe and helpful for patients with Multiple Myeloma. The study team will provide more information.
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Comparing Different Treatments for Patients with Blood Cancer
The purpose of this study is to test two drug combinations for people with a type of blood cancer called Waldenström's Macroglobulinemia or Lymphoplasmacytic Lymphoma. We want to see if the new drug combination is safe and helps fight the cancer. The study is for volunteers who have not been treated for this cancer before.
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Testing the Study Drug KTX-1001 for The Treatment of Multiple Myeloma
The goal of this study is to learn more about the study drug KTX-1001. We want to find out if this drug is safe for patients with multiple myeloma that has returned or didn't respond to treatment. We also want to see if patients can handle the taking the drug.
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Testing the Study Drug INX-315 for Patients with Advanced Cancer
The purpose of this study is to learn more about the study drug INX-315. We want to see if this study drug is a safe treatment for patients with certain types of advanced cancer or cancer that has spread to other parts of the body. Study team will provide more information on eligibility criteria.
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A Study of the Drug Efruxifermin for Treating Liver Diseases and Scarring of the Liver
Non-alcoholic steatohepatitis and metabolic dysfunction-associated steatohepatitis are types of fatty liver disease that cause scarring of the liver. We want to learn more about the safety and effects when using the study drug Efruxifermin to treat these diseases.
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Using Technology to Improve Care for Teens with Inflammatory Bowel Disease
Inflammatory bowel disease (IBD) affects the digestive system. Types of IBD include Ulcerative Colitis and Crohn's disease. The purpose of this study is to find out if text messaging can be used to help care for people with IBD. Volunteers must have a smartphone with text messaging.
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A Study of the Drug Efruxifermin for Patients with Liver Disease
The goal of this study is to find out if a drug called efruxifermin can help people with liver scarring caused by liver disease. We also want to know if the drug is safe and helpful for patients. Volunteers must have a liver disease where too much fat builds up, causing inflammation and scarring. Study team will provide more information.
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Learning More About the Long-Term Use of the Study Drug Staccato Alprazolam for Prolonged Seizures
The purpose of this study is to learn more about the long-term use of the study drug Staccato Alprazolam. We want to see how well the study drug works when used long-term for patients with a history of prolonged seizures. We also want to learn more about the safety and side effects that may be caused by the study drug.
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Comparing Ways to Improve Blood Flow in Newborns' Lungs
The purpose of this study is to looks at two different methods to help increase blood flow in the lungs of newborn babies. One method uses a shunt, which is a small tube, and the other uses a stent, which is a tiny mesh-like device. We want to learn if one of the two options is better than the other.
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Testing a New Study Device for Mitral Valve Dysfunction
The purpose of this study is to test a new study device called the Cephea Mitral Valve System for the treatment of this condition. We want to learn more about the safety and effectiveness of this device.
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Looking for Volunteers Interested in COVID-19 Related Studies
The purpose of this study is to make a list of people who want to volunteer for research and COVID-19 vaccine studies. This list is called the STRIVE registry. People on the list will be contacted about new studies they might join. Joining the list does not mean you have to join any future studies.
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Studying an Arm Injection to Help Walking After Stroke
The purpose of this study is to see if a medicine called Xeomin, given as an injection in the arm, helps people who had a stroke walk better and keep their balance. The study will use simple movement tests and a small device to measure how people walk. The goal is to learn if this treatment can help people move more easily after a stroke.
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Testing Cardiac Rehab for Amyloidosis
The study aims to find out if exercise programs can help people with this condition feel better.
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Can Atorvastatin Prevent Dementia, Disability or Heart Disease in Older Adults?
This study is also known as PREVENTABLE, and the goal is to learn if taking a statin could help older adults live well for longer by preventing dementia, disability, or heart disease. This study is one of the largest research studies in adults aged 75 and older. Our researchers make it easy for people to join the study by connecting with them at home and sending the medication directly to their homes. They also check participants' health records and call them once a year to keep track of their progress. For more information, visit the PREVENTABLE website at www.preventabletrial.org or contact the study contact below.
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Improving the Care and Health of Children, Adolescents, and Young Adults with Inflammatory Bowel Disease
The purpose of this study is to improve the care and health for children, teens, and young adults with IBD (Inflammatory Bowel Disease). We want to gather information from your regular care visits to help improve the care for patients with inflammatory bowel disease. For example, we could learn which type of medication works best for treating this disease.
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