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Learning More About the Effects of Oxytocin on the Nervous System
Oxytocin is a naturally occurring hormone. The purpose of this study is to see how oxytocin affects the nervous system. We will be looking at how pupils change after an oxytocin injection.
Study Topics
Healthy Volunteers Neurology Disorders Bones, Joints, Muscles
Testing AURN001 Injection for Treatment of Corneal Endothelial Dysfunction
The purpose of this study is to test a possible new treatment for polycythemia vera. The study drug is called ISIS 702843. We want to find out how well the study drug works and if there are side effects when using it.
Study Topics
Adding High Dose Radiation to the Usual Treatment for Non-Small Cell Lung Cancer
The purpose of this study is to find out if we can delay your cancer getting worse and help you live longer by giving high-dose radiation therapy directly to your lung tumor. This treatment will be done before the usual treatment for locally-advanced non-small cell lung cancer. We want to find out if this approach is better or worse than the usual treatment.
Study Topics
Testing a New Treatment for Myeloproliferative Disorders
The purpose of this study is to see how well the study drug, INCA033989, works for treating myeloproliferative disorders. We want to find what effects, if any, this therapy may have on people. We also want to find out what is the highest dose that can be given without causing severe side effects.
Study Topics
Learning More About Intestinal Health in Infants and Children with a New Imaging Device
The purpose of this study is to learn more about a new type of imaging device called the iThera MSOT Acuity. We want to find out how well the device works for measuring intestinal health.
Study Topics
Healthy Volunteers Stomach and Intestines Children, Infants, Teen Health
A study of the Drug Budesonide, Glycopyrronium, and Formoterol Fumarate to Treat Chronic Obstructive Pulmonary Disease
The purpose if this study is to learn more about the study drugs Budesonide, Glycopyrronium, and Formoterol Fumarate. We want to see how well the study drugs work for preventing chronic obstructive pulmonary disease flare-ups.
Study Topics
Study of the Drug AMG 355 in Patients with Advanced Solid Tumors
The purpose of this study is to learn more about the study drug AMG 355. We want to see how well the study drug works for treating advanced solid tumors. We also want to learn more about the side effects that may be caused by the study drug.
Study Topics
Cancer Cancer: Colon, Rectum, Anus Cancer: Lung Cancer: Skin Cancer: Stomach and Intestines
Study of MK-0616 for Reducing Major Heart-Related Events
The purpose of this study is to test a drug called MK-0616. It will be tested in adults at high risk for a major heart related event. Examples of major heart-related events include heart attack and stroke. We want to find out how well MK-0616 reduces the risk of major heart-related events. We also want to see how MK-0616 affects cholesterol and other blood tests related to heart health.
Study Topics
Testing a Radiation-Based Treatment for Prostate Cancer that has Spread
The purpose of this study is to find out if radiation treatment with Lutetium Lu 177 Dotatate can shrink or slow the growth of prostate cancer. We want to find out if this approach is better or worse than the usual approach.
Study Topics
Treating Asthma with AZD4604
The purpose of this study is to see how well the new study drug, AZD4604, works in treating asthma. We also want to learn more about the side effects of this drug.
Study Topics
Learning More About Treating Plaque Psoriasis with Deucravacitinib
The purpose of this study is to find out how well the study drug, deucravacitinib, works for treating psoriasis on the palms, soles, and genital area. We also want to learn more about side effects that may be caused by the study drug.
Study Topics
Learning More About Blood Tests to Determine if a Cancer Patient Will Respond to Treatment
Not all patients treated with immune checkpoint inhibitors respond with tumor shrinkage. Many patients have serious side effects. The purpose of this study is to develop blood tests that can help determine if patients will respond to treatment and develop side effects.
Study Topics
Treating Dravet Syndrome with Fenfluramine Hydrochloride
The purpose of this study is to find out how well the study drug, fenfluramine hydrochloride, works for treating Dravet syndrome. We also want to learn more about side effects that may be caused by the study drug.
Study Topics
Using Belumosudil to Treat Chronic Graft Versus Host Disease
The purpose of this study is to learn more about the study drug Belumosudil. We want to see how well the study drug works for treating chronic graft versus host disease. We also want to learn more about the side effects that may be caused by the study drug.
Study Topics
Learning More About Treating Nonrelapsing Secondary Progressive Multiple Sclerosis with Frexalimab
The purpose of this study is to see if the study drug, Frexalimab, can keep multiple sclerosis from getting worse. We also want to learn more about the side effects that may be caused by the study drug.
Study Topics
Treating Uncontrolled Seizures with the Study Drug NRTX-1001
The purpose of this study is to learn more about treating uncontrolled seizures with the study drug NRTX-1001. We want to see how the study drug works and find out what side effects may be caused.
Study Topics
Using Selumetinib for Treating Neurofibromatosis Type 1 and Low-Grade Glioma
The purpose of this study is to see how well a drug called selumetinib works for treating patients with neurofibromatosis type 1 associated low-grade glioma. Low-grade glioma is a type of cancer that affects the nervous system. We also want to see how well selumetinib works at improving vision in patients with low-grade glioma of the optic pathway. The optic pathway includes parts of the eye and brain that help us see.
Study Topics
Cancer Cancer: Brain, Nervous System, Spinal Cord Cancer: Children, Teens
Treating Low-grade Serous Ovarian or Peritoneal Cancer with Letrozole
The purpose of this study is to find out if we can we lower the chance of your ovarian or peritoneal cancer growing or spreading with the study drug Letrozole. We want to find out if this approach is better or worse than the usual approach for treating this type of cancer.
Study Topics
Cancer Cancer: Rare Cancers Cancer: Sarcoma (Bone, Muscle, Soft Tissue) Cancer: Women's Cancer
Study of COVID19 Infections Using At-Home Rapid Diagnostic Test Kits and Online Data Gathering
The purpose of this study is to collect information about our community's COVID-19 exposures, symptoms, and health care visits due to the virus.
Study Topics
Helping Those with Serious Mental Illness Stop Smoking
People who smoke and have serious mental illness are 2-8 times more likely to fail standard stop smoking treatments. The purpose of this study is to look at ways to help this population in their efforts to quit smoking. The study tests two different cost-effective methods designed to help those with serious mental illness quit smoking. This study will be done completely online.
Study Topics
Mental Health Substance Use (Alcohol, Illegal Drugs, Tobacco)