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Electromagnetic Treatment for Stroke Recovery
The purpose of this study is to see if a wearable device helps stroke recovery. The device uses low-frequency electromagnetic fields to activate the brain. Volunteers must have had stroke onset 4 to 21 days ago.
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A Study of the Drug Efruxifermin for Patients with Liver Disease
The goal of this study is to find out if a drug called efruxifermin can help people with liver scarring caused by liver disease. We also want to know if the drug is safe and helpful for patients. Volunteers must have a liver disease where too much fat builds up, causing inflammation and scarring. Study team will provide more information.
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Comparing Ways to Improve Blood Flow in Newborns' Lungs
The purpose of this study is to looks at two different methods to help increase blood flow in the lungs of newborn babies. One method uses a shunt, which is a small tube, and the other uses a stent, which is a tiny mesh-like device. We want to learn if one of the two options is better than the other.
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Testing a New Study Device for Mitral Valve Dysfunction
The purpose of this study is to test a new study device called the Cephea Mitral Valve System for the treatment of this condition. We want to learn more about the safety and effectiveness of this device.
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Looking for Volunteers Interested in COVID-19 Related Studies
The purpose of this study is to make a list of people who want to volunteer for research and COVID-19 vaccine studies. This list is called the STRIVE registry. People on the list will be contacted about new studies they might join. Joining the list does not mean you have to join any future studies.
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A Study of the Drug Batoclimab for Treatment of Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
Chronic inflammatory demyelinating polyneuropathy (CIDP) is an autoimmune disorder. The purpose of this study is to learn more about the study drug Batoclimab. We want to see if this study drug is safe and helps people with CIDP.
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Can Atorvastatin Prevent Dementia, Disability or Heart Disease in Older Adults?
This study is also known as PREVENTABLE, and the goal is to learn if taking a statin could help older adults live well for longer by preventing dementia, disability, or heart disease. This study is one of the largest research studies in adults aged 75 and older. Our researchers make it easy for people to join the study by connecting with them at home and sending the medication directly to their homes. They also check participants' health records and call them once a year to keep track of their progress. For more information, visit the PREVENTABLE website at www.preventabletrial.org or contact the study contact below.
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Testing Cardiac Rehab for Amyloidosis
The study aims to find out if exercise programs can help people with this condition feel better.
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Improving the Care and Health of Children, Adolescents, and Young Adults with Inflammatory Bowel Disease
The purpose of this study is to improve the care and health for children, teens, and young adults with IBD (Inflammatory Bowel Disease). We want to gather information from your regular care visits to help improve the care for patients with inflammatory bowel disease. For example, we could learn which type of medication works best for treating this disease.
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Studying the Medicine COM701 to Help Keep Ovarian Cancer Away
The purpose of this study is to learn more about a study medicine called COM701. Our researchers want to find out if this medicine is safe and works as a maintenance treatment for people whose ovarian cancer has come back after finishing chemotherapy.
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Finding Signs of Hearing Problems in Babies with Cytomegalovirus Infection Present at Birth
The purpose of this study is to learn more about tests that can be used to show how a baby's hearing will be affected if they have cytomegalovirus (CMV) infection present at birth.
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Infectious Diseases Screening and Prevention Children, Infants, Teen Health Ears, Nose, Throat, Mouth
Studying a New Medicine for a Kidney Disease Called FSGS
Focal segmental glomerulosclerosis (FSGS) is a kidney disease that slowly gets worse over time. It damages the tiny filters in the kidneys, causing scars and making the filters leaky. This lets protein leak into the urine. The purpose of this study is to learn more about a new medicine for this disease. Our researchers want to see if it can lower the amount of protein in the urine and help slow kidney damage when taken with a common blood pressure medicine called an ARB.
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Can Regular Phone Calls with a Care Manager Improve Quality of Life for People with Post-Traumatic Epilepsy
The purpose of this study is to find out if regular phone calls from a care manager can help patients with post-traumatic epilepsy and symptoms of anxiety and/or depression. The care manager will talk about anxiety, depression, seizures and side effects. They will also provide you with brief therapy sessions. We want to know if this approach helps improve emotional quality of life.
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Studying a New Medicine for Kids and Teens with Generalized Myasthenia Gravis
Generalized myasthenia gravis is a disease that makes muscles weak because the body's defense system attacks the spot where nerves and muscles connect. The purpose of this study is to learn more about a new medicine for kids and teens with this disease. Our researchers want to find out if the medicine is safe, how it works inside the body, and if it helps kids feel better and do everyday things more easily.
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Rare Disease Brain and Memory Children, Infants, Teen Health
Studying Causes of Heart Failure
This purpose of this study is to understand what causes heart failure. Some people with early-stage heart failure might not know they have it because they feel fine, while others may have many or few symptoms. We want to learn why some people get heart failure and how to better classify it for targeted treatments. We are recruiting volunteers with and without heart failure to learn more.
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New Treatment for ANCA Vasculitis in Kids and Teens
Active ANCA-associated Vasculitis is a disease where the body's immune system accidentally attacks its own small to medium-sized blood vessels. This makes the blood vessels swollen and damaged. The purpose of this study is to learn more about a treatment to help kids and teens with this disease. We want to see if the treatment called avacopan is safe and helpful.
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Rare Disease Arthritis, Lupus, and Autoimmune Disorders Children, Infants, Teen Health
New Treatment for ANCA Vasculitis in Kids and Teens
This study wants to see if the medicine Metformin XR can help older people with this heart problem. We also want to learn about the side effects and see if it can make their health better.
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Studying a New Medicine for Crohn's Disease
The purpose of this study is to learn more about a new medicine for people with Crohn's disease who have not gotten better with other treatments. Volunteers in the study will get either the new medicine or a look-alike with no medicine in it. Our researchers will check if the new medicine works and is safe.
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