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Studying a Blood Test to Guide Cancer Treatment After Surgery
The purpose of this study is to see if a blood test can help doctors decide who needs extra cancer treatment after surgery for bladder, kidney. Ureter, or urethra cancer. The blood test looks for cancer DNA in the blood. If the test finds cancer DNA, patients may get one or two cancer drugs, or they may be watched closely.
Study Topics
Cancer Cancer: Kidney, Liver, Pancreas Cancer: Urinary and Bladder
Studying New Glucose Sensors for People with Diabetes
The purpose of this study is to see how well new glucose sensors work. These sensors help people with diabetes track their blood sugar. The study compares the new sensors to ones already sold in stores.
Study Topics
Learning the Best Ways to Treat Broken Bones and Reduce Future Fractures
The purpose of this study is to learn more about different ways to care for patients after they break a bone and to reduce your chances of having another fracture. We are looking for volunteers with a recent bone break and who have a regular doctor. They also must not have certain health conditions like cancer, severe kidney disease, or other bone diseases. The study team will provide more information.
Study Topics
Managing Osteoarthritis Pain with Movement and Healthy Eating at Home
Osteoarthritis is a condition that causes pain and stiffness in the joints, often in the hips and knees. The purpose of this study is to find ways to help people with chronic pain due to this condition. We want to find a drug-free way to better manage symptoms through movement and healthy eating. The study is done entirely at home with virtual visits and assessments. The study team will provide more details.
Study Topics
Pain Arthritis, Lupus, and Autoimmune Disorders Weight, Metabolism, Nutrition Bones, Joints, Muscles
Comparing Different Migraine Medicines
The purpose of this study is to learn more about three migraine medicines: atogepant, propranolol, and topiramate. Our researchers want to see which one helps prevent migraines the best. Volunteers in the study will try one medicine and keep track of their headaches. The results will help doctors and patients choose the best medicine for migraine prevention.
Study Topics
Helping People with HIV Quit Smoking Using Apps
The purpose of this study is to learn more about two different ways to help people with HIV quit smoking. The first way is to use the app called QuitStart along with the use of nicotine gum and patches. The second way is to use the app called Learn to Quit-HIV (LTQ-H) along with the use of nicotine gum and patches. We will compare each way to understand the pros and cons of each approach. We are looking for volunteers who have HIV and have smoked cigarettes every day in the past 30 days.
Study Topics
HIV/AIDS Substance Use (Alcohol, Illegal Drugs, Tobacco) Wellness and Lifestyle
Studying Hair Loss and Family History
The purpose of this study is to learn more about what might cause a kind of hair loss called Frontal Fibrosing Alopecia. We are looking for Black or African American women who have this condition. If you join the study, you will be asked to answer a short survey, have pictures taken of your scalp, and give a saliva sample so we can look at your DNA. We are also looking for family members-whether they have hair loss or not-to take part. This is not a treatment study.
Study Topics
Studying Aspirin Use During Pregnancy
The purpose of this study is to learn more about aspirin use during pregnancy. We want to see if using more aspirin can help lower the chance of having a baby too early or stillborn. Our researchers will compare two different aspirin doses to see which works better for moms and babies. We are looking for volunteers who are between 10 and almost 16 weeks pregnant and who have had a baby born more than five weeks early in the past.
Study Topics
Studying Pump Chemotherapy For Colorectal Cancer that Spread to the Liver
Hepatic arterial infusion (HAI) chemotherapy is a way to give cancer medicine straight into the liver using a small pump. The purpose of this study is to see if using this type of chemotherapy with regular chemotherapy can help people with colorectal cancer that has spread to the liver. Doctors will compare people who get both treatments to people who get only regular chemotherapy. The goal is to find out which treatment helps patients live longer and feel better.
Study Topics
Helping Patients Manage Pain and Medicine After Surgery
The purpose of this research is to learn which of three treatments works best for helping people manage pain and use medicine after surgery. We also want to understand how pain, mood, and medicine use change after surgery. One of the treatments is a type of talk therapy called motivational interviewing, which may help people feel better and use less pain medicine. If you join the study, you will be placed into a group by chance-like flipping a coin. We are looking for volunteers who are scheduled for elective orthopedic surgery at Atrium Health Wake Forest Baptist.
Study Topics
How Muscles Affect Walking as We Get Older
The purpose of this study is to find out why some older adults lose the ability to walk easily. Our researchers will test how changes in muscles, like strength and energy, affect walking and fitness. The goal is to find ways to help people stay active and independent as they age. To learn more, please visit our website here: www.sommastudy.com/somma2
Study Topics
Aging Men's Health Pain Wellness and Lifestyle Women's Health Bones, Joints, Muscles
Studying Bone and Kidney Problems in Patients with Diabetes and Nerve Damage in their Feet
The purpose of this study is to learn how your kidneys affect the bones in your feet. We believe that healthy kidneys help keep your foot bones strong. Having diabetes and nerve damage can increase your chances of having kidney and foot problems. You will help us understand more about how they are related which will ultimately help us discover tests and treatments to prevent diabetes related foot problems.
Study Topics
Study of Two Medicines for Diabetes, Blood Pressure, and Heart Disease
The purpose of this study is to find out if taking two medicines together helps people with type 2 diabetes, high blood pressure, and heart disease. Our researchers will compare the medicines to a look-alike pill with no medicine inside. The goal is to see if the medicines can lower the chance of serious health problems like heart attacks or strokes.
Study Topics
Learning About Patient Experiences with HyQvia for Nerve Disease
Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a long-term illness where the body's defense system attacks the nerves, making people feel weak and numb. This study aims to learn about the experiences of people with this disease who are using a medicine called HyQvia. We want to understand their symptoms, how the disease affects their daily lives, and their treatment experiences. The information we gather may help others in the future by improving our understanding of CIDP and making future research studies better.
Study Topics
Comparing Two Treatments for People With Low Tumor Burden Follicular Lymphoma
The purpose of this study is to learn more about the drug mosunetuzumab. We want to see if this drug works better than the usual treatment for a type of cancer called low tumor burden follicular lymphoma.
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Testing Genes for Cystic Fibrosis Diabetes
The purpose of this study is to understand why people with cystic fibrosis get diabetes. Both diseases are caused by changes in DNA and other molecules in the blood. These changes can cause thick mucus in the pancreas, which damages cells that make insulin, leading to diabetes.
Study Topics
Genetic Disorders Lung Health Children, Infants, Teen Health Diabetes
Testing Seizure Medicine for Kids
The purpose of this study is to test a liquid medicine called zonisamide for kids with seizures. We want to see how the medicine moves in the body and if it is safe. The study is for kids aged 1 month to 17 years who have partial-onset seizures.
Study Topics
Studying an App to Help Cancer Patients Sleep Better
The purpose of this study is to test two wellness apps and see which one helps cancer patients sleep better. We want to find out how these apps affect sleep, immune health, and overall well-being of blood cancer patients during treatment.
Study Topics
Comparing Two Drugs for Patients with Nodular Lymphocyte-predominant Hodgkin Lymphoma
The goal of this study is to test two different drugs for people with Nodular lymphocyte-predominant Hodgkin lymphoma. We want to see if the drug mosunetuzumab works better than the drug rituximab. We also want to see which drug helps people live longer without their disease getting worse. We are doing this study to find out if this new treatment is better or worse than the usual treatment for this type of lymphoma.
Study Topics
Preventing Heart Disease in Psoriasis Patients
The purpose of this study is to test a new care program to help people with psoriasis lower their risk of heart disease. Examples of health risks are high cholesterol, high blood pressure, diabetes, and smoking that can lead to heart attacks or strokes. We want to see if a care coordinator can help patients manage their heart health better.
Study Topics