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Testing a New Study Device for Tricuspid Regurgitation
The purpose of this study is to test a study device called Edwards EVOQUE system for the treatment of this condition. We want to learn more about the safety and effectiveness of this device.
Study Topics
Using Inclisiran to Lower the Risk of Heart Attacks and Strokes in Adults with Heart Disease
The purpose of this study is to find out if the study drug, Inclisiran, can lower the risk of events like heart attacks and strokes. The study drug will be taken along with a medicine that can lower cholesterol. This study is being done at our High Point location.
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A Study of the Drug Aficamten for Hypertrophic Cardiomyopathy
The purpose of this study is to learn more about the study drug aficamten for this condition. We want to learn more about the safety and tolerability of this drug.
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A Study of the VBX Device for Patients with Peripheral Artery Disease
The purpose of this study is to learn more about the VBX Stent Graft study device. We want to see if the study device is safe and works well for patients with complex iliac occlusive disease, a form of peripheral artery disease. We will compare this study device to another device called Bare Metal Stents and see which one will work better.
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Studying a New Study Catheter to Treat Rapid Heartbeat
The purpose of this study is to learn more about a new study catheter. We want to see if this catheter can help treat episodes of rapid heartbeat in patients with heart problems not caused by blocked arteries or heart attacks. We want to learn more about the safety and effectiveness of this catheter.
Study Topics
Learning More About the Neuroguard IEP Direct System for Treatment of Carotid Artery Narrowing
The purpose of this study is to learn more about a new study device called the Neuroguard IEP Direct System to treat patients with narrowed arteries in their neck that supply blood to their brain. The treatment involves making a small cut on one side of your neck to place the device.
Study Topics
Using Mavacamten to Treat Adolescents with Cardiomyopathy
Obstructive Hypertrophic Cardiomyopathy (HCM) is a heart condition that makes it hard for the heart to pump blood and may make a person feel weak and tired. The purpose of this study is to see if the study drug, mavacamten, helps young people with obstructive HCM.
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Learning More About the Effects of Very Low-Nicotine Cigarettes on the Heart
The purpose of this study is to learn more about the effects of very low-nicotine cigarettes on the heart.
Study Topics
Heart Health Substance Use (Alcohol, Illegal Drugs, Tobacco)
Testing a New Home-Use Device for Detection of Irregular Heartbeats
The purpose of this study is to test a new home-use device called SANSA. We want to see if this device helps detect irregular heartbeats compared to the current tests already used by doctors. If successful, this device could help more people get diagnosed and treated for their irregular heartbeats.
Study Topics
Finding Out if Inclisiran Can Help Prevent Heart-Related Events Like Heart Attack or Stroke
The purpose of the study is to find out if the study drug, inclisiran, can prevent heart-related events by lowering LDL-cholesterol in the blood. LDL cholesterol is also known as bad cholesterol.
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Testing a New Study Device for Mitral Valve Regurgitation
The purpose of this study is to test a study device called the CardioMech Mitral Valve Repair System for patients with this condition. We want to learn about the safety and effectiveness of this device.
Study Topics
Testing a New Heart Device for Patients with Heart Failure
The purpose of this study is to learn more about a study device called the OPTIMIZER Smart for patients with heart failure. We want to gather information on this device and see if it helps improve heart function and quality of life.
Study Topics
Treating Relapsing Multiple Sclerosis with BIIB091
The purpose of this study is to find out how well a new drug called BIIB091 works for treating relapsing multiple sclerosis. We also want to find out how well the body can handle taking the study drug.
Study Topics
Testing a Study Device for Pulmonary Regurgitation
The purpose of this study is to test a study device called Medtronic Harmony Transcatheter Pulmonary Valve for the treatment of this condition. We want to learn more about the safety and effectiveness of this device.
Study Topics
Using Anifrolumab to Treat Lupus Nephritis
The purpose of this study is to learn more about a new lupus nephritis treatment called Anifrolumab. We want to find out how well it works and what side effects it may have.
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Comparing Ways to Improve Blood Flow in Newborns' Lungs
The purpose of this study is to looks at two different methods to help increase blood flow in the lungs of newborn babies. One method uses a shunt, which is a small tube, and the other uses a stent, which is a tiny mesh-like device. We want to learn if one of the two options is better than the other.
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Testing a New Study Device for Mitral Valve Dysfunction
The purpose of this study is to test a new study device called the Cephea Mitral Valve System for the treatment of this condition. We want to learn more about the safety and effectiveness of this device.
Study Topics
Testing a New Study Device for Patients with Heart Failure
The purpose of this study is to test a new study device called the CCM-D System. We want to see if this device is safe and effective for patients with heart failure and a heart that is not pumping out as much blood as it should with each beat.
Study Topics
Looking Into the Need of Blood Thinners as Treatment for Atrial Fibrillation
Blood thinning drugs are usually used to treat atrial fibrillation. Atrial fibrillation is when the heart has an irregular and often very fast heart rhythm. Blood thinners lower the risk of stroke but also increase the risk of bleeding. It may not be necessary for people who have short or infrequent atrial fibrillation to take blood thinners. The purpose of this study is to find out if it is safe to stop blood-thinning medication during long periods of normal heart rhythm.
Study Topics
Finding Out How Well the Study Drug, HU6, Works for Treating Patients with Obesity and Heart Failure
The purpose of this study is to learn more about the study drug, HU6. The study will help us find out how the study drug affects weight loss and the ability to exercise. It will also help us see what side effects may be caused by the study drug.
Study Topics