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Testing a New Study Device for Tricuspid Regurgitation
The purpose of this study is to test a study device called Edwards EVOQUE system for the treatment of this condition. We want to learn more about the safety and effectiveness of this device.
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A Study of the VBX Device for Patients with Peripheral Artery Disease
The purpose of this study is to learn more about the VBX Stent Graft study device. We want to see if the study device is safe and works well for patients with complex iliac occlusive disease, a form of peripheral artery disease. We will compare this study device to another device called Bare Metal Stents and see which one will work better.
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Testing a Study Device for Pulmonary Regurgitation
The purpose of this study is to test a study device called Medtronic Harmony Transcatheter Pulmonary Valve for the treatment of this condition. We want to learn more about the safety and effectiveness of this device.
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A Study of the Drug Aficamten for Hypertrophic Cardiomyopathy
The purpose of this study is to learn more about the study drug aficamten for this condition. We want to learn more about the safety and tolerability of this drug.
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Studying a New Study Catheter to Treat Rapid Heartbeat
The purpose of this study is to learn more about a new study catheter. We want to see if this catheter can help treat episodes of rapid heartbeat in patients with heart problems not caused by blocked arteries or heart attacks. We want to learn more about the safety and effectiveness of this catheter.
Study Topics
Testing a New Home-Use Device for Detection of Irregular Heartbeats
The purpose of this study is to test a new home-use device called SANSA. We want to see if this device helps detect irregular heartbeats compared to the current tests already used by doctors. If successful, this device could help more people get diagnosed and treated for their irregular heartbeats.
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Using Mavacamten to Treat Adolescents with Cardiomyopathy
Obstructive Hypertrophic Cardiomyopathy (HCM) is a heart condition that makes it hard for the heart to pump blood and may make a person feel weak and tired. The purpose of this study is to see if the study drug, mavacamten, helps young people with obstructive HCM.
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Testing a Study Device for Treatment of Sudden Tear in the Aorta
The purpose of this study is to find out if the study device called AMDS is safe and works well for treating this condition. We want to see if this device can help heal the aorta's walls and reduce the need for surgery.
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Testing a Study Device for Chronic Venous Insufficiency
Chronic venous insufficiency happens when blood gets stuck in the veins of the legs because the valves do not work right. This study wants to see if the study device Venclose™ digiRF™ Generator and its catheters are safe and good at treating this problem. We want to know if these devices can help fix the veins in the legs and stop them from leaking. The study will also check if the devices are safe to use.
Study Topics
Comparing MitraClip and Surgery for Mitral Valve Repair
The purpose of this study is to test a study device called the MitraClipTM Device for patients with this condition and who are at moderate risk of surgery.
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Using the GORE® Device to Treat Heart Lesions
Aortic disease may cause wounds in the blood vessels near the heart. We want to learn more about the safety and how well the study device, GORE® Ascending Stent Graft, treats these wounds.
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Testing the Study Device Impella for Patients with Severe Heart Disease
The purpose of this study is to learn more about the study device called Impella. We want to see if this device can be used during a high-risk heart procedure in patients with weak heart function on the left side. We want to learn if this device will improve symptoms and heart function after the procedure when compared to the standard of care treatment.
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Testing a New Study Device for Mitral Valve Regurgitation
The purpose of this study is to test a study device called the CardioMech Mitral Valve Repair System for patients with this condition. We want to learn about the safety and effectiveness of this device.
Study Topics
Testing a New Study Device for Patients with Heart Failure
The purpose of this study is to test a new study device called the CCM-D System. We want to see if this device is safe and effective for patients with heart failure and a heart that is not pumping out as much blood as it should with each beat.
Study Topics
Testing a New Heart Valve for Mitral Regurgitation
The purpose of this study is to test a new device called the AltaValve System. We want to see if it can help treat leaky heart valves. We want to find out if the device is safe and works well for people who cannot have open-heart surgery. The study is for adults with mitral valve regurgitation.
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Testing a New Heart Device for Stroke Prevention
The purpose of this study is to test a new heart device called the Laminar System. We want to see if this device is safe and works well for people with a heart condition called non-valvular atrial fibrillation. The study will help doctors understand if this device can prevent strokes in these patients.
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Learning More About the Neuroguard IEP Direct System for Treatment of Carotid Artery Narrowing
The purpose of this study is to learn more about a new study device called the Neuroguard IEP Direct System to treat patients with narrowed arteries in their neck that supply blood to their brain. The treatment involves making a small cut on one side of your neck to place the device.
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Cell Treatment for Urinary Incontinence
Stress urinary incontinence (SUI) is an accidental loss of urine due to laughing, coughing, or sneezing. The purpose of this study is to learn more about using a type of cell treatment to help women with SUI. This study focuses on women with SUI that did not get better after surgical treatment.
Study Topics
Comparing Ways to Improve Blood Flow in Newborns' Lungs
The purpose of this study is to looks at two different methods to help increase blood flow in the lungs of newborn babies. One method uses a shunt, which is a small tube, and the other uses a stent, which is a tiny mesh-like device. We want to learn if one of the two options is better than the other.
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Testing a New Study Device for Mitral Valve Dysfunction
The purpose of this study is to test a new study device called the Cephea Mitral Valve System for the treatment of this condition. We want to learn more about the safety and effectiveness of this device.
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