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How Salt Affects Blood Pressure in Young Adults Who Were Born Prematurely
The purpose of this study is to learn about how salt in the diet affects blood pressure in young adults who were born prematurely. We also want to find out if the medication, allopurinol, can change how salt in the diet affects blood pressure.
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Healthy Volunteers Heart Health Kidneys, Liver, Pancreas Children, Infants, Teen Health
Studying a New Medicine for People with Heart Disease and Obesity
Atherosclerotic cardiovascular disease happens when fatty buildup blocks blood vessels and makes it harder for blood to flow. The purpose of this study is to learn more about a new medicine for people who already have this condition and are overweight or have obesity. The goal is to see if the medicine can help lower their chances of having heart problems in the future.
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Testing a New Study Device for Tricuspid Regurgitation
The purpose of this study is to test a study device called Edwards EVOQUE system for the treatment of this condition. We want to learn more about the safety and effectiveness of this device.
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A Study of the VBX Device for Patients with Peripheral Artery Disease
The purpose of this study is to learn more about the VBX Stent Graft study device. We want to see if the study device is safe and works well for patients with complex iliac occlusive disease, a form of peripheral artery disease. We will compare this study device to another device called Bare Metal Stents and see which one will work better.
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Testing a Study Device for Pulmonary Regurgitation
The purpose of this study is to test a study device called Medtronic Harmony Transcatheter Pulmonary Valve for the treatment of this condition. We want to learn more about the safety and effectiveness of this device.
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Studying a New Study Catheter to Treat Rapid Heartbeat
The purpose of this study is to learn more about a new study catheter. We want to see if this catheter can help treat episodes of rapid heartbeat in patients with heart problems not caused by blocked arteries or heart attacks. We want to learn more about the safety and effectiveness of this catheter.
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Using Mavacamten to Treat Adolescents with Cardiomyopathy
Obstructive Hypertrophic Cardiomyopathy (HCM) is a heart condition that makes it hard for the heart to pump blood and may make a person feel weak and tired. The purpose of this study is to see if the study drug, mavacamten, helps young people with obstructive HCM.
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Testing a Study Device for Treatment of Sudden Tear in the Aorta
The purpose of this study is to find out if the study device called AMDS is safe and works well for treating this condition. We want to see if this device can help heal the aorta's walls and reduce the need for surgery.
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Using the GORE® Device to Treat Heart Lesions
Aortic disease may cause wounds in the blood vessels near the heart. We want to learn more about the safety and how well the study device, GORE® Ascending Stent Graft, treats these wounds.
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Neurology Disorders Arthritis, Lupus, and Autoimmune Disorders Bones, Joints, Muscles
Studying a New Study Device for Severe Blood Flow Problems in Limbs
Chronic Limb-Threatening Ischemia means that blood flow to a leg or foot is very low because the blood vessels are blocked. The purpose of this study is to collect information about a device called the LimFlow System, which is used to treat this condition. Our researchers want to find out how safe and effective this device is.
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Testing the Study Drug Pelacarsen to Slow Calcium Build-Up in the Heart Valve
The purpose of this study to learn more about the study drug pelacarsen for patients with calcific aortic valve stenosis. We want to see if the study drug can help safely slow the progression of calcium build-up on the heart valve. Calcium build-up causes narrowing and restricting of blood flow from the heart to the rest of the body.
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Studying a New Medicine to Treat Hypertrophic Cardiomyopathy
Hypertrophic cardiomyopathy is a disease that makes the heart muscle too thick which can make it harder for the heart to pump blood. The purpose of this study is to learn more about a new medicine for this disease called EDG-7500. We want to see if this medicine is safe and useful to treat patients.
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Studying a Mobile App for Heart Rehab Post-Valve Procedure
The purpose of this study is to find out if an at home mobile app can help improve heart health. The app is a heart rehab program and involves a health exercise program. Volunteers in the study will be put into one of three groups: no app, using the app for 12 weeks, or using the app for 24 weeks. We are looking for volunteers who have recently had, or will soon have, a heart valve procedure to fix their aortic, mitral, or tricuspid valve.
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Testing a New Study Device for Patients with Heart Failure
The purpose of this study is to test a new study device called the CCM-D System. We want to see if this device is safe and effective for patients with heart failure and a heart that is not pumping out as much blood as it should with each beat.
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Testing a New Heart Device for Stroke Prevention
The purpose of this study is to test a new heart device called the Laminar System. We want to see if this device is safe and works well for people with a heart condition called non-valvular atrial fibrillation. The study will help doctors understand if this device can prevent strokes in these patients.
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Testing a New Heart Valve for Mitral Regurgitation
The purpose of this study is to test a new device called the AltaValve System. We want to see if it can help treat leaky heart valves. We want to find out if the device is safe and works well for people who cannot have open-heart surgery. The study is for adults with mitral valve regurgitation.
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Helping Patients with Cancer Quit Smoking With New Therapy
The purpose of this study is to learn more about two types of diabetes medicines. We want to see which medicine type helps lower the risk of heart and kidney problems. We are looking for volunteers with type 2 diabetes and a history of heart disease or have high risk for heart disease that are patients of Elizabeth Internal Medicine and Carmel Family Physicians.
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Comparing Ways to Improve Blood Flow in Newborns' Lungs
The purpose of this study is to looks at two different methods to help increase blood flow in the lungs of newborn babies. One method uses a shunt, which is a small tube, and the other uses a stent, which is a tiny mesh-like device. We want to learn if one of the two options is better than the other.
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Testing a New Study Device for Mitral Valve Dysfunction
The purpose of this study is to test a new study device called the Cephea Mitral Valve System for the treatment of this condition. We want to learn more about the safety and effectiveness of this device.
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Testing Cardiac Rehab for Amyloidosis
The study aims to find out if exercise programs can help people with this condition feel better.
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