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Using Technology to Improve Care for Teens with Inflammatory Bowel Disease
Inflammatory bowel disease (IBD) affects the digestive system. Types of IBD include Ulcerative Colitis and Crohn's disease. The purpose of this study is to find out if text messaging can be used to help care for people with IBD. Volunteers must have a smartphone with text messaging.
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Taking a Look at Stigma and Discrimination Associated with Chronic Tic Disorders
The purpose of this study is to create a new way to measure how stigma and discrimination effects people with chronic tic disorders. The Tourette discrimination-stigmatization scale will be tested through interviews with people who have tics. Caregivers, doctors, and advocates will also be interviewed. We want to better understand the challenges that people with chronic tic disorder might face.
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Learning More About Treating Migraine in Children and Young Adults with Rimegepant
The purpose of this study is to learn how well the study drug, Rimegepant, treats migraines in children and young adults. We also want to learn more about the possible side effects of the study drug.
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Electromagnetic Treatment for Stroke Recovery
The purpose of this study is to see if a wearable device helps stroke recovery. The device uses low-frequency electromagnetic fields to activate the brain. Volunteers must have had stroke onset 4 to 21 days ago.
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Treatment for Migraine and Mood
Many people with migraine have challenges related to mood. The purpose of this study is to test two different treatments for improving both migraine and mood.
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Testing the Study Drug NRTX-1001 for Drug-Resistant Epilepsy in the Brain
The purpose of this study is to test if the study drug NRTX-1001 cell therapy is safe for people with drug-resistant mesial temporal lobe epilepsy (MTLE). Another goal is to see if it can reduce the number of seizures you have.
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Looking at How Chemotherapy Effects Older Adults
The purpose of this study is to look at how chemotherapy effects older adults. We want to learn more about predicting chemotherapy side effects in older adults. We also want to see if chemotherapy causes changes in the body that are associated with aging.
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Studying a New COVID-19 Vaccine among Patients who have Received a Cell Therapy
The purpose of this study is to see if a new vaccine called GEO-CM04S1can help people who have received a cell therapy build protection from COVID-19. We want to compare this new vaccine to the current COVID-19 vaccines and see which one will work better.
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Testing a New Home-Use Device for Detection of Irregular Heartbeats
The purpose of this study is to test a new home-use device called SANSA. We want to see if this device helps detect irregular heartbeats compared to the current tests already used by doctors. If successful, this device could help more people get diagnosed and treated for their irregular heartbeats.
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Learning More About How Sedatives Affect Tobacco Cravings and Withdrawal Symptoms
The purpose of this research is to learn more about the effects of sedative medication on the mood, behavior, and brains of smokers. We are not testing a treatment for quitting smoking. We are interested in how the medication affects tobacco craving and withdrawal symptoms. Taking part in this research will involve 5 visits and last about 5 weeks.
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Healthy Volunteers Substance Use (Alcohol, Illegal Drugs, Tobacco)
A Study of the Drug Efruxifermin for Patients with Liver Disease
The goal of this study is to find out if a drug called efruxifermin can help people with liver scarring caused by liver disease. We also want to know if the drug is safe and helpful for patients. Volunteers must have a liver disease where too much fat builds up, causing inflammation and scarring. Study team will provide more information.
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Finding Out if Inclisiran Can Help Prevent Heart-Related Events Like Heart Attack or Stroke
The purpose of the study is to find out if the study drug, inclisiran, can prevent heart-related events by lowering LDL-cholesterol in the blood. LDL cholesterol is also known as bad cholesterol.
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Study to Find Out How Well Pritelivir Works for Treating Skin Lesions Caused by Herpes
In patients with an impaired immune system, herpes ulcers are usually extensive, deep and cause severe pain. The standard treatment sometimes doesn't work for these patients. The purpose of this study is to see how well the study drug, Pritelivir, may work for this group of patients. We also want to find out what side effects may be caused by the study drug.
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Studying a New Pneumococcal Disease Vaccine Among Healthy Toddlers
Your child is being asked to join this study because they are healthy, between 12 to 15 months old, and have had 3 doses of Prevnar 20®. The study will test a new vaccine to see if it can protect against a germ that causes infections in children. The goal is to check if the vaccine is safe and helps the body make antibodies to fight the germ.
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Healthy Volunteers Infectious Diseases Screening and Prevention Children, Infants, Teen Health
Treating Inclusion Body Myositis with the Study Drug ABC008
Inclusion body myositis (IBM) is an inflammatory autoimmune disorder of skeletal muscle. With IBM harmful immune cells attack muscle causing muscle weakness. The study drug ABC008 has been designed to reduce the number of these harmful immune cells. The purpose of this study is to find out how well the study drug works for treating IBM.
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Looking at How a High-Calorie Diet May Affect White Bloods Cells Called Monocytes
The purpose of this study is to find out how a high-calorie Western diet effects a type of white blood cell called a monocyte. Study participants will be provided with all meals and snacks. Please copy and paste the following link into your web browser to complete a survey to see if you might qualify for this study. https://redcap.link/03p0zexc
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Testing a New Study Device for Mitral Valve Regurgitation
The purpose of this study is to test a study device called the CardioMech Mitral Valve Repair System for patients with this condition. We want to learn about the safety and effectiveness of this device.
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Learning More About Treating Multiple Myeloma with Talquetamab
The purpose of this study is to see how well the study drug, talquetamab, works for treating multiple myeloma. We want to find out if this approach is better than usual treatment.
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Learning More About a New Treatment for Diabetic Macular Edema
Diabetic macular edema (DME) is the gathering of fluid in the retina area of the eye. The purpose of this study is to see how well the study drug, RO7200220, works for treating DME.
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