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Understanding How Breast Size Affects Migraine Headaches
The purpose of this study is to find out if breast tissue affects headache and neck pain. Some studies show that having large breasts might be linked to pain in the head and neck, but we do not fully understand the reasons for this. In this study, we will monitor how headache features change before and after plastic surgery. We are looking for volunteers who are seeing Plastic Surgery for breast reduction (reduction mammoplasty) or excess skin removal (panniculectomy) procedures.
Study Topics
Stopping a GLP-1 Medicine - A Study to Determine How the Brain Changes
The purpose of this study is to learn how the brain changes when people stop taking a kind of weight loss medicine called GLP-1. We will use brain scans and short surveys to help us understand what happens in the brain after stopping the medicine. We are looking for people who are currently taking GLP-1 medicine, have lost at least 10% of their starting weight, and plan to stop taking it. At this time, we are only accepting volunteers who are already taking a GLP-1.
Study Topics
Weight, Metabolism, Nutrition Wellness and Lifestyle Brain and Memory
Testing a New Formula of Cladribine for Patients with Generalized Myasthenia Gravis
Generalized myasthenia gravis is a condition where the body's defense system attacks the muscles, making them weak and tired. The purpose of this study is to find out how well a new medicine called Cladribine works compared to a fake medicine. We also want to see how well patients can handle the new medicine.
Study Topics
Testing Two Different Ways to Help Unblock Stomachs
The purpose of this study is to compare two different treatments to help people with blocked stomachs, usually because of cancer. We want to see which treatment works better and can lower the chance of symptoms like pain, nausea or vomiting from coming back.
Study Topics
Stomach and Intestines Cancer Cancer: Stomach and Intestines
CARES Study: Listening to Caregivers
The purpose of this study is to learn more about the health of caregivers. We want to understand how life experiences before and during caregiving for someone with dementia may impact physical and emotional health over time. The goal is to find better ways to help caregivers feel supported. This study is done completely over the phone. Volunteers will get one call for an interview and then a follow-up call to connect them to resources, if needed.
Study Topics
Studying the Medicine Belimumab for Adults with Lupus
The purpose of this study is to learn more about the medicine belimumab for adults who were recently diagnosed with lupus. We want to see if the medicine can make symptoms better and reduce the need for other medicines that may cause problems over time. We will also will check the safety of this medicine when used for three years.
Study Topics
Testing if Oxytocin Helps You Feel Less Heat Pain After a Mild Sunburn
The purpose of this study is to see how oxytocin affects your ability to feel touch and heat. They will give you oxytocin through an IV (a tube in your vein). They will test this on normal skin and on skin that has a mild sunburn from UV-B light. In this study, you will either get oxytocin or a placebo (a fake solution that doesn't do anything).
Study Topics
Things that May Predict Memory Decline or Dementia in Adults (Healthy Brain Study)
This study is being done to look at changes in memory, thinking and brain structure in older adults. We will also study how the body processes sugar and how that may relate to change in brain function over time.
Study Topics
Testing Spinal Cord Stimulation for Stiffness and Pain in Stiff Person Syndrome
Stiff person syndrome is a rare disease that makes your muscles very stiff and can cause painful muscle spasms. This study wants to find out if using spinal cord stimulation can help make these symptoms better.
Study Topics
A Study of the Drug Reparixin for Patients with Myelofibrosis
The purpose of this study is to learn more about the study drug Reparixin. This study drug is for people with a type of blood cancer called myelofibrosis. We want to find out if Reparixin is safe and if it helps treat this cancer.
Study Topics
Studying the Safety of the Flu Vaccine and COVID-19 Vaccine Among Pregnant People
The purpose of this study is to find out if it is safe for pregnant people to get the flu and COVID-19 vaccines together. We will compare getting both shots on the same day or 7-14 days apart.
Study Topics
A Study of the Drug LBP-EC01 for the Treatment of Urinary Tract Infections
The goal of this study is to learn more about the drug LBP-EC01. We want to see if it is safe and helpful for treating females with frequent or recurrent urinary tract infection (UTI) caused by a bacteria called E. coli but particularly E. coli that is resistant to at least one antibiotic.
Study Topics
Studying the Drug MT-7117 for Patients with a Rare Blood Disorder
The purpose of this study is to learn more about the study drug MT-7117. We want to see if this study drug is useful for patients with a rare blood disorder called Erythropoietic Protoporphyria. We also want to see if this study drug is tolerable to take.
Study Topics
Testing the Study Drug Levocarnitine to Prevent Liver Damage in Leukemia or Lymphoma Patients
The purpose of this study to learn more about the study drug Levocarnitine. We want to see if this study drug protects the liver from chemotherapy for leukemia or lymphoma.
Study Topics
Exploring a New Program to Care for Rural Patients with Chronic Pain
The purpose of this study is to test a new program for patients in rural areas with chronic pain. We want to see if this program can help patients better manage their pain and daily functioning by working with a nurse care manager.
Study Topics
Testing the Study Drug DFP-10917 for Patients with Acute Myeloid Leukemia
The purpose of this study is to find out more about the drug DFP-10917. We want to see if it is safe and helpful for treating people with acute myeloid leukemia.
Study Topics
Testing the Study Drug Lutikizumab for Severe Skin Disease
Hidradenitis suppurativa is a skin problem that causes painful bumps and boils under the skin. The purpose of this study is to find out if the study drug lutikizumab is safe and useful for treating this skin problem.
Study Topics
Testing a New Study Device for Brain Aneurysms
A saccular intracranial aneurysm is a balloon-like bump in a brain blood vessel that can burst and cause big problems. The purpose of this study is to see if a new device is safe and helpful for treating this condition.
Study Topics
Using the TheraBionic Device to Treat Advanced Pancreatic Cancer
The purpose of this study is to find out how the TheraBionic device will affect pancreatic cancer. The TheraBionic device is a small portable device. We want to see if the device will prevent cancer growth.
Study Topics