Search Studies
Studying Vitamin C Levels and Blood Cancer Treatment Outcomes
The purpose of this study is to see if vitamin C levels affect how well treatments work for people with certain types of blood cancer. We will also look at specific genes that might affect vitamin C in the body. This study will help us understand if vitamin C can improve treatment results for these cancers. We are looking for volunteers with acute myeloid leukemia, myelodysplastic syndromes, or chronic myelomonocytic leukemia.
Study Topics
Learning More About Treating Large B-cell Lymphoma or Follicular Lymphoma with Additional Treatment
The purpose of this study is to find out if we can lower the chance of your diffuse large B-cell lymphoma growing or spreading by adding treatment to the usual approach. The usual approach is to watch the patient's condition unless symptoms appear or change. We want to know which approach is better.
Study Topics
Treating Neuroendocrine Carcinoma with Atezolizumab
The purpose of this study is to see if adding the study drug, atezolizumab, to the usual cancer treatment helps people with a type of cancer that starts outside the lungs called neuroendocrine carcinoma.
Study Topics
Studying Diabetes Medicine for Heart and Kidney Health
The purpose of this study is to learn more about two types of diabetes medicines. We want to see which medicine type helps lower the risk of heart and kidney problems. We are looking for volunteers with type 2 diabetes and a history of heart disease or have high risk for heart disease that are patients of Elizabeth Internal Medicine and Carmel Family Physicians.
Study Topics
Testing the Study Drug KTX-1001 for The Treatment of Multiple Myeloma
The goal of this study is to learn more about the study drug KTX-1001. We want to find out if this drug is safe for patients with multiple myeloma that has returned or didn't respond to treatment. We also want to see if patients can handle the taking the drug.
Study Topics
Combining the Study Drug, REGN5458, with Other Treatments for Multiple Myeloma
The main purpose of this study is to find out if the study drug, REGN5458, can be given safely with other multiple myeloma treatments. We also want to find out what dose of REGN5458 should be used.
Study Topics
Testing the Study Drug INX-315 for Patients with Advanced Cancer
The purpose of this study is to learn more about the study drug INX-315. We want to see if this study drug is a safe treatment for patients with certain types of advanced cancer or cancer that has spread to other parts of the body. Study team will provide more information on eligibility criteria.
Study Topics
Looking Into the Need of Blood Thinners as Treatment for Atrial Fibrillation
Blood thinning drugs are usually used to treat atrial fibrillation. Atrial fibrillation is when the heart has an irregular and often very fast heart rhythm. Blood thinners lower the risk of stroke but also increase the risk of bleeding. It may not be necessary for people who have short or infrequent atrial fibrillation to take blood thinners. The purpose of this study is to find out if it is safe to stop blood-thinning medication during long periods of normal heart rhythm.
Study Topics
Testing the Study Drug PRO1160 for Advanced Kidney, Throat, and Blood Cancers
The purpose of this study is to learn more about the new drug PRO1160. We want to see if it is safe and helpful for treating patients with cancer that didn't fully respond to treatment or has come back. Volunteers must have kidney cancer, throat cancer, or a type of blood cancer called non-Hodgkin lymphoma.
Study Topics
Cancer Cancer: Ear, Nose, Mouth, Throat Cancer: Kidney, Liver, Pancreas Cancer: Lymphoma
Using Dexpramipexole for the Treatment of Severe Eosinophilic Asthma
The purpose of this study is to find out how well the study drug dexpramipexole works for the treatment of severe asthma. We also want to learn more about the safety of the study drug.
Study Topics
Treating Hyperactivity in Children with Down Syndrome using Guanfacine
The purpose of this study is to learn more about how well the study drug, guanfacine, can treat hyperactivity in children with Down syndrome.
Study Topics
Care Program for Adults with Epilepsy Dealing with Anxiety and/or Depression
The purpose of this study is to find out if emotional quality of life can be improved for those with epilepsy and anxiety and/or depression. We want to see if regular calls or visits with a care manager can help with the anxiety and/or depression symptoms.
Study Topics
A Study of the Drug Efruxifermin for Treating Liver Diseases and Scarring of the Liver
Non-alcoholic steatohepatitis and metabolic dysfunction-associated steatohepatitis are types of fatty liver disease that cause scarring of the liver. We want to learn more about the safety and effects when using the study drug Efruxifermin to treat these diseases.
Study Topics
Learning More About Online Group Yoga to Help With Depression
The purpose of this study is to find out if yoga can be just as helpful as therapy for treating depression. We want to understand why some people may benefit more from one program or the other.
Study Topics
Learning More About the Neuroguard IEP Direct System for Treatment of Carotid Artery Narrowing
The purpose of this study is to learn more about a new study device called the Neuroguard IEP Direct System to treat patients with narrowed arteries in their neck that supply blood to their brain. The treatment involves making a small cut on one side of your neck to place the device.
Study Topics
Study of DSP-5336 for Treatment of Leukemia
Acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL) and acute leukemia are types of cancer of the blood and bone marrow. This study will help us learn more about a new drug, DSP-5336, that is being tested for treatment of AML, ALL and acute leukemia. The purpose of this study is to find out how safe DSP-5336 is at different doses.
Study Topics
Study of Selinexor for Treating High-Grade Glioma in Pediatric Patients
A glioma is a type of cancer that occurs in the brain or spine. Diffuse intrinsic pontine glioma is a type of high-grade glioma. The purpose of this study is to look at how well selinexor works when given to children and young adults with high-grade glioma or diffuse intrinsic pontine glioma. We also want to find the highest dose of selinexor that we can give safely along with radiation therapy.
Study Topics
Cancer Cancer: Brain, Nervous System, Spinal Cord Children, Infants, Teen Health
A Study of the Drug Lutikizumab for Treatment of Ulcerative Colitis
The purpose of this study is to learn more about the study drug Lutikizumab. We want to see if this study drug is safe and effective for treatment of ulcerative colitis. We also want to compare this study drug to the current drug Adalimumab.
Study Topics
Using Cancer Cells in the Blood to Determine the Type of Chemotherapy that Will Benefit Colon Cancer Patients After Surgery
The purpose of this study is to help us learn more about using circulating tumor DNA (ctDNA) results to decide what chemo to offer patients after colon cancer surgery. ctDNA is DNA that has been released from tumor cells into your blood. Finding ctDNA in your blood means that there are likely small amounts of cancer after surgery. This study will help us find out if using ctDNA results to decide on treatment is better than the usual approach.
Study Topics
Electromagnetic Treatment for Stroke Recovery
The purpose of this study is to see if a wearable device helps stroke recovery. The device uses low-frequency electromagnetic fields to activate the brain. Volunteers must have had stroke onset 4 to 21 days ago.
Study Topics