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Testing the Study Drug CIN-102 for Diabetic Gastroparesis Treatment
The purpose of this study is to better understand how well the NeuroBlate System works for treating brain metastases. The system will be used along with laser interstitial thermal therapy (LITT). The NeuroBlate System uses laser light energy to heat and destroy the tumor. The LITT procedure includes a biopsy of brain tissue. The procedures are considered to be minimally invasive.
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Testing a New Lung Cancer Risk Test
The purpose of this study is to test the Percepta Nasal Swab, a new nasal swab test for lung cancer risk. We want to see how useful this test is for determining lung cancer risk when a lung nodule is found during cancer screening.
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Treating Low-Risk, Early Stage Breast Cancer with Hormonal Therapy
The usual treatment for low-risk breast cancer is radiation and hormonal therapy. The purpose of this study is to find out how well hormonal therapy alone will work. We want to find out if this approach is better or worse than the usual approach.
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Testing a New Study Device for Tricuspid Regurgitation
The purpose of this study is to test a study device called Edwards EVOQUE system for the treatment of this condition. We want to learn more about the safety and effectiveness of this device.
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Using Inclisiran to Lower the Risk of Heart Attacks and Strokes in Adults with Heart Disease
The purpose of this study is to find out if the study drug, Inclisiran, can lower the risk of events like heart attacks and strokes. The study drug will be taken along with a medicine that can lower cholesterol. This study is being done at our High Point location.
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A Study of the Drug Aficamten for Hypertrophic Cardiomyopathy
The purpose of this study is to learn more about the study drug aficamten for this condition. We want to learn more about the safety and tolerability of this drug.
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Quitting Smoking and Managing Daily Challenges
The purpose of this study is to learn more about the mood, behavior and brains of people who smoke. We want to find look at how daily hassles might affect how emotional distress is managed during an attempt to stop smoking. This study does not offer a treatment to stop smoking.
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Healthy Volunteers Substance Use (Alcohol, Illegal Drugs, Tobacco)
A Study of the VBX Device for Patients with Peripheral Artery Disease
The purpose of this study is to learn more about the VBX Stent Graft study device. We want to see if the study device is safe and works well for patients with complex iliac occlusive disease, a form of peripheral artery disease. We will compare this study device to another device called Bare Metal Stents and see which one will work better.
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Study to Find Out if the Study Drug, LN145, Works Well for Treating Nonsmall Cell Lung Cancer
The purpose of this study is to find out if the study drug, LN145, works well for treating nonsmall cell lung cancer.
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Studying a New Study Catheter to Treat Rapid Heartbeat
The purpose of this study is to learn more about a new study catheter. We want to see if this catheter can help treat episodes of rapid heartbeat in patients with heart problems not caused by blocked arteries or heart attacks. We want to learn more about the safety and effectiveness of this catheter.
Study Topics
Comparing Two Different Methods of Surgery to Treat Osteosarcoma that Has Spread to the Lungs
The purpose of this study is to compare two different surgery methods for people with osteosarcoma that has spread to the lung. We want to find out which surgery method is better. One method is called open thoracic surgery. It is done through a single large cut between the ribs, opens the chest, and removes the cancer. The other method is called thoracoscopy. It is done through several small incisions and uses a small camera to help with removing the cancer. Both methods are considered standard treatment.
Study Topics
Comparing Two Different Methods of Surgery to Treat Osteosarcoma that Has Spread to the Lungs
The purpose of this study is to compare two different surgery methods for people with osteosarcoma that has spread to the lung. We want to find out which surgery method is better. One method is called open thoracic surgery. It is done through a single large cut between the ribs, opens the chest, and removes the cancer. The other method is called thoracoscopy. It is done through several small incisions and uses a small camera to help with removing the cancer. Both methods are considered standard treatment.
Study Topics
Using Upadacitinib to Treat Arthritis in Children and Young People
The purpose of this study is to learn more about treating arthritis in children and young people with the study drug, upadacitinib. We want to see if this treatment works better than the usual treatment.
Study Topics
Arthritis, Lupus, and Autoimmune Disorders Children, Infants, Teen Health
Arterial Stiffness, Cognition and Equol (ACE) Study: Learning More About the Benefits of Soy-Based Supplement for Brain Health
Equol is a soy-based supplement. The purpose of this study is to learn more about the positive effects Equol may have on brain health. We want to find out if it can slow the progression of stiffening arteries, small blood vessel disease and memory decline.
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Learning Moe About Using Nivolumab for Treatment of Newly Diagnosed Primary Mediastinal B-cell Lymphoma
Primary mediastinal B-cell lymphoma (PMBCL) is a type of cancer in the upper chest between the lungs and behind the breastbone. The purpose of this study is to find out how well the study drug, nivolumab, works for treating PMBCL.
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The Vaccine Preferences Study
The goal of this study is to identify best practices in communicating information about new vaccines to communities that need them most. We want to survey Black and African American communities and learn more about their opinions and preferences for vaccine communication.
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Healthy Volunteers HIV/AIDS Infectious Diseases Mental Health
Learning More About Treating Cancer Near the Spinal Cord with Radiosurgery and Pembrolizumab
The purpose of this study is to find out what effects pembrolizumab and radiosurgery may have on you and your cancer. We want to see if this treatment can reduce the size of cancer that has spread near the spinal cord. Radiosurgery involves radiation in a large dose to destroy your cancer. It does not involve cutting your tumor out.
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Learning More About the Motivation to Continue a Treatment Regimen
The purpose of this study is to learn more about the opinions and preferences of older adults living with chronic conditions such as human immunodeficiency virus (HIV). We want to learn more about their experience with medication regimens.
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Testing the Study Drug CIN-103 for Treatment of Irritable Bowel Syndrome with Predominant Diarrhea
The purpose of this study is to learn more about the study drug CIN-103 for the treatment of irritable bowel syndrome with predominant diarrhea. We want to see if the study drug can help people have less stomach pain and more solid stools. We also want to learn more about the side effects that may be caused by the study drug.
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