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Testing a New Study Device for Severe Blood Flow Problems in Limbs
The purpose of this study is to collect information about a device called the LimFlow System, which is used to treat this condition. We want to find out how safe and effective this device is.
Study Topics
Testing New Treatments for Large B-Cell Lymphoma
The purpose of this study is to test a new mix of three drugs called lenalidomide, mosunetuzumab, and polatuzumab vedotin. We want to see if these drugs are safe and helpful for people with a type of blood cancer called diffuse large B-cell lymphoma. This study is for patients whose cancer has come back or did not get better with other treatments. We also want to find the highest dose that is still safe for patients.
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Testing the Study Device Impella for Patients with Severe Heart Disease
The purpose of this study is to learn more about the study device called Impella. We want to see if this device can be used during a high-risk heart procedure in patients with weak heart function on the left side. We want to learn if this device will improve symptoms and heart function after the procedure when compared to the standard of care treatment.
Study Topics
A Study of the Drug Valacyclovir for Babies at Risk of Herpes
The purpose of this study is to learn more about the study drug Valacyclovir. We want to figure out the best amount of the study drug that is needed for babies who may have been exposed to herpes when they were born.
Study Topics
Testing the Study Drug CIN-102 for Diabetic Gastroparesis Treatment
Diabetic gastroparesis is a condition where the stomach takes too long to empty its contents. The purpose of this study is to learn more about the study drug CIN-102 for treatment of this condition. We want to test the safety and possible side effects of this study drug.
Study Topics
Testing the anti-cancer drug erdafitinib for brain cancers
The purpose of this study is to test the good and bad effects of the study drug, erdafitinib. We want to find out if the study drug is better or worse than other treatments for brain cancer.
Study Topics
Testing a New Lung Cancer Risk Test
The purpose of this study is to test the Percepta Nasal Swab, a new nasal swab test for lung cancer risk. We want to see how useful this test is for determining lung cancer risk when a lung nodule is found during cancer screening.
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Learning More About How HIV and Marijuana Affect the Brain
The purpose of this study is to learn more about how HIV and marijuana affect the brain. This will help us understand how changes in the brain affect the way we think and behave.
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Healthy Volunteers HIV/AIDS Substance Use (Alcohol, Illegal Drugs, Tobacco)
Learning More About the Treatment of Bleeding, Clotting or Non-neoplastic Blood Disorder
The main purpose of this study is to look at the how well the treatments for non-neoplastic blood disorders work. We also want to look at the side effects that may be caused by the treatments.
Study Topics
A Study of the Drug AZD5492 for Blood Cancer
The purpose of this study to learn more about the study drug AZD5492. We want to see if this study drug is safe and helpful for treating blood cancers that have not gotten better with other treatments. We need volunteers with certain types of blood cancer like B-cell non-Hodgkin's lymphoma or chronic lymphocytic leukemia/small lymphocytic lymphoma. The study team will provide more information.
Study Topics
Learning More About Using ABBV-383 to Treat Amyloidosis
The purpose of this study is to find out how safe and effective the study drug, ABBV-383, is in treating people with with amyloidosis.
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Can Metformin Help with Decline in Memory?
The purpose of this study is to see how well the medicine Metformin can help patients with memory decline.
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Learning More About Using Ivonescimab to Treat Lung Cancer
The purpose of this research study is to see if the study drug, ivonescimab, is safe and useful to treat people with a type of cancer called metastatic squamous non-small cell lung cancer.
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Virtual Reality Rehabilitation Method for Treating a Type of Vision Loss Called Visual Hemianopia
The purpose of this study is to see how well a new rehabilitation method works for treating visual hemianopia. Visual hemianopia is loss of half the vision in the right or left side of each eye. This rehabilitation may help restore vision.
Study Topics
Studying a New Cancer Therapy for Advanced Solid Tumors
X-PACT is a new cancer treatment that uses a drug called psoralen and a low dose of X-rays. This study wants to see if this treatment is safe and helpful for patients. Volunteers need to have advanced head and neck cancer, soft tissue sarcoma, breast cancer, melanoma, or other solid tumors that didn't get better with other treatments.
Study Topics
Collecting Data from Hemophilia Patients
The purpose of this study is to collect data on a blood disorder called hemophilia. The data will be used to improve the care of patients.
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Heart Health Cancer Cancer: Children, Teens Children, Infants, Teen Health
Testing a New Drug Combination for Patients with Myelofibrosis
The purpose of this study is to learn more about using two drugs called navtemadlin and ruxolitinib. We want to see if taking both drugs together helps treat patients with myelofibrosis. We also want to see if people can handle taking the drugs.
Study Topics
Effects of a Low-Carbohydrate and Low-Fat Diet in Adults with Mild Memory Loss (BEAT-AD Study)
The purpose of this study is to look at the effects of a low-carbohydrate diet and low-fat diet in adults with mild memory loss. We want to see if changes in diet can improve memory.
Study Topics
Studying the Drug AZD7798 for Patients with Crohn's Disease
We are doing this study to find out if the study drug AZD7798 works well and is safe for treating Crohn's disease. We also want to learn more about Crohn's disease and the health problems it causes. AZD7798 targets a specific type of immune cell that we think might be causing inflammation in the gut for people with Crohn's disease.
Study Topics
The Use of Muscle Fiber Fragments to Treat the Loss of Bladder Control in Women
The purpose of this study is to find out if injecting muscle fiber fragments into the bladder can treat bladder leakage in women. Taking part in this study will include seven study visits in a year.
Study Topics