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Studying the Medicine Triptorelin to Protect Ovaries During Chemotherapy
The purpose of this study is to learn more about a medicine called triptorelin. We want to find out if it can help protect the ovaries of teens and young adults during cancer treatment. Some cancer drugs can damage the ovaries and make it harder to have children later in life. Our researchers are studying this medicine to see if it works better than the usual methods used to protect the ovaries. We are looking for women volunteers with cancer who are receiving a specific type of chemotherapy called an alkylating agent.
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Studying Access to Food and its Impact on Blood Pressure
The purpose of this study is to learn more about access to food and blood pressure. Our researchers would like to explore different ways of helping people get better access to food and see if it can help improve their blood pressure. Some people will get help from a community health worker, and others may get meals made for people with high blood pressure. The goal is to find out which way works best. We are looking for volunteers who have high blood pressure and experience a lack of regular access to food.
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Opinions, Social Issues Weight, Metabolism, Nutrition Wellness and Lifestyle Blood Pressure
Understanding How Breast Size Affects Migraine Headaches
The purpose of this study is to find out if breast tissue affects headache and neck pain. Some studies show that having large breasts might be linked to pain in the head and neck, but we do not fully understand the reasons for this. In this study, we will monitor how headache features change before and after plastic surgery. We are looking for volunteers who are seeing Plastic Surgery for breast reduction (reduction mammoplasty) or excess skin removal (panniculectomy) procedures.
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Studying a New Medicine to Lower Bad Cholesterol
The purpose of this study is to learn more about a new medicine called AZD0780. We want to see if this medicine can lower bad cholesterol and help prevent heart attacks or strokes. This study is for volunteers with heart disease or who are at high risk of heart problems. The goal is to see if the new medicine works better than current treatments and is safe for patients.
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Studying the Drug VX-670 for Adults with Myotonic Dystrophy Type 1
The purpose of this study is to learn more about the study drug VX-670. We want to find out if it is safe and if adults with myotonic dystrophy type 1 can handle it well.
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Testing a New Formula of Cladribine for Patients with Generalized Myasthenia Gravis
Generalized myasthenia gravis is a condition where the body's defense system attacks the muscles, making them weak and tired. The purpose of this study is to find out how well a new medicine called Cladribine works compared to a fake medicine. We also want to see how well patients can handle the new medicine.
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Stem Cell Transplant After Chemotherapy for Lymphoma Patients
The purpose of this study is to find out if giving a stem cell transplant after chemotherapy helps people with Peripheral T-cell Lymphoma stay healthy longer. Doctors will compare people who get the transplant to people who do not. The goal is to see which way works better to keep the cancer from coming back.
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Studying Cirtuvivint for Blood Cancer
The purpose of this study is to learn more about a medicine called cirtuvivint for certain blood cancers. Our researchers will study this medicine by itself or together with another pill called ASTX727. We want to learn how safe these medicines are, find the best dose, and see how they affect the cancer. This study is for volunteers with myelodysplastic syndromes (MDS) or acute myeloid leukemia (AML).
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Exercise and Coaching Program for People With Heart Failure
The purpose of this study is to learn how a group exercise and coaching program affects people with heart failure with preserved ejection fraction. Our researchers will look at whether this program is safe and if it can help people be more active, move more easily, and feel better in their daily lives. This study will also help researchers learn if this type of program is practical and helpful for future patients.
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Study of the Drug Inotuzumab Ozogamicin in Patients with Disseminated B-cell Lymphoblastic Lymphoma
The purpose of this study is to find out if the study drug, Inotuzumab Ozogamicin, can help treat certain types of leukemia. The study drug will be given along with the usual chemotherapy.
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CARES Study: Listening to Caregivers
The purpose of this study is to learn more about the health of caregivers. We want to understand how life experiences before and during caregiving for someone with dementia may impact physical and emotional health over time. The goal is to find better ways to help caregivers feel supported. This study is done completely over the phone. Volunteers will get one call for an interview and then a follow-up call to connect them to resources, if needed.
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Learning More About The Medicine Duvelisib T-cell Lymphoma
The purpose of this study is to learn more about treating peripheral T-cell lymphoma with the study drug Duvelisib or Azacitidine. One of the study drugs will be given along with the usual treatment. We want to see how well the combination treatment works. We also want to learn more about possible side effects.
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Learning How E-Cigarettes Affect Brain Health Over Time
The purpose of this study is to find out how using e-cigarettes for a long time affects the brain. We will compare people who switched to e-cigarettes with people who quit all tobacco and nicotine. The goal is to learn if switching to e-cigarettes helps the brain as much as quitting smoking.
Study Topics
Substance Use (Alcohol, Illegal Drugs, Tobacco) Brain and Memory
Studying a New Medicine for Certain Types of Heart Failure
The purpose of this study is to learn more about the study medicine called VS 041. We want to see if this medicine is safe for people with a certain type of heart failure called heart failure with preserved ejection fraction (HFpEF). Our researchers will also look at how this medicine affects blood markers linked to heart health. What we learn may help guide future treatments.
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Studying Plixorafenib for Cancers with BRAF Gene Changes
The purpose of this study is to learn more about the medicine plixorafenib. We want to see if this medicine can help people whose cancer has a change in the BRAF gene. The medicine is being studied to see if it works and if it is safe. People in the study will take the medicine and be watched closely for any changes or side effects.
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Exploring a New Program to Care for Rural Patients with Chronic Pain
The purpose of this study is to test a new program for patients in rural areas with chronic pain. We want to see if this program can help patients better manage their pain and daily functioning by working with a nurse care manager.
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Things that May Predict Memory Decline or Dementia in Adults (Healthy Brain Study)
This study is being done to look at changes in memory, thinking and brain structure in older adults. We will also study how the body processes sugar and how that may relate to change in brain function over time.
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Using the TheraBionic Device to Treat Advanced Pancreatic Cancer
The purpose of this study is to find out how the TheraBionic device will affect pancreatic cancer. The TheraBionic device is a small portable device. We want to see if the device will prevent cancer growth.
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Studying New Glucose Sensors for People with Diabetes
The purpose of this study is to see how well new glucose sensors work. These sensors help people with diabetes track their blood sugar. The study compares the new sensors to ones already sold in stores.
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Studying a Blood Test to Guide Cancer Treatment After Surgery
The purpose of this study is to see if a blood test can help doctors decide who needs extra cancer treatment after surgery for bladder, kidney. Ureter, or urethra cancer. The blood test looks for cancer DNA in the blood. If the test finds cancer DNA, patients may get one or two cancer drugs, or they may be watched closely.
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