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Studying the Drug Tulisokibart for Patients with Active Crohn's Disease
The purpose of this study is to test a new drug called Tulisokibart. We want to see if this drug is safe and useful for people with Crohn's disease. We will compare this study drug to a placebo drug to see how well it works.
Study Topics
Using Upadacitinib to Treat Arthritis in Children and Young People
The purpose of this study is to learn more about treating arthritis in children and young people with the study drug, upadacitinib. We want to see if this treatment works better than the usual treatment.
Study Topics
Arthritis, Lupus, and Autoimmune Disorders Children, Infants, Teen Health
A Study of the Drug Deucravacitinib for Patients with Lupus
The purpose of this study is to learn more about the study drug Deucravacitinib. We want to see how well the study drug works for treating Lupus. We also want to learn more about the side effects that may be caused by the study drug.
Study Topics
Studying the Drug AZD7798 for Patients with Crohn's Disease
We are doing this study to find out if the study drug AZD7798 works well and is safe for treating Crohn's disease. We also want to learn more about Crohn's disease and the health problems it causes. AZD7798 targets a specific type of immune cell that we think might be causing inflammation in the gut for people with Crohn's disease.
Study Topics
Collecting Data on Patients with Generalized Myasthenia Gravis
General Myasthenia Gravis is a rare disease that makes it hard for nerves and muscles to work together. This study collects information about people with this disease in a patient registry. The registry helps scientists learn new things that might help others in the future.
Study Topics
Neurology Disorders Rare Disease Arthritis, Lupus, and Autoimmune Disorders
Comparing Two Study Drugs for Treatment of Vasculitis
Eosinophilic Granulomatosis with Polyangiitis is a disease that makes small blood vessels swell up in people with asthma. We want to see how two different study drugs, depemokimab and mepolizumab, work to treat this disease. We also want to learn about the possible side effects of each study drug.
Study Topics
A Study of the Drug Batoclimab for Treatment of Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
Chronic inflammatory demyelinating polyneuropathy (CIDP) is an autoimmune disorder. The purpose of this study is to learn more about the study drug Batoclimab. We want to see if this study drug is safe and helps people with CIDP.
Study Topics
A Study of the Drug ALPN-303 for Patients with Autoimmune Cytopenias
An autoimmune cytopenia is a condition when your immune system, which usually fights germs, accidentally attacks your own blood cells. This study wants to find out if the study drug ALPN-303 is safe and helpful for treating this condition.
Study Topics
New Treatment for ANCA Vasculitis in Kids and Teens
Active ANCA-associated Vasculitis is a disease where the body's immune system accidentally attacks its own small to medium-sized blood vessels. This makes the blood vessels swollen and damaged. The purpose of this study is to learn more about a treatment to help kids and teens with this disease. We want to see if the treatment called avacopan is safe and helpful.
Study Topics
Rare Disease Arthritis, Lupus, and Autoimmune Disorders Children, Infants, Teen Health
The Osteoarthritis Prevention Study (TOPS)
Exercise and diet have been shown to help with the treatment of osteoarthritis. The purpose of this study is to find out if exercise and diet prevents osteoarthritis.
Study Topics
Arthritis, Lupus, and Autoimmune Disorders Weight, Metabolism, Nutrition
Learning More About Treating Systemic Lupus Erythematosus with Litifilimab
The purpose of this study is to find out if the study drug, Litifilimab, can improve symptoms of lupus. We want to see if the study drug can reduce disease activity and inflammation
Study Topics
Using Anifrolumab to Treat Lupus Nephritis
The purpose of this study is to learn more about a new lupus nephritis treatment called Anifrolumab. We want to find out how well it works and what side effects it may have.
Study Topics
Testing RINVOQ for the Treatment of Adults with Lupus
The purpose of this study is to find out how well the study drug RINVOQ works for treating adults with systemic lupus erythematosus. We also want to find out how safe the study drug is for patients. RINVOQ is an FDA approved medication for other conditions.
Study Topics
Testing New Ulcerative Colitis Treatment
The purpose of this study is to learn more about a new study drug called Lutikizumab. We want to see if this study drug is safe and works well for treating moderate to severe ulcerative colitis. We will compare this study drug to another drug called Adalimumab.
Study Topics
Arthritis, Lupus, and Autoimmune Disorders Stomach and Intestines
Testing a New Treatment for Muscle Weakness
The purpose of this study is to test a new treatment called YTB323 for people with generalized myasthenia gravis. We want to see if YTB323 is safe and helps improve muscle strength. Participants will receive the treatment through an IV infusion.
Study Topics
Neurology Disorders Arthritis, Lupus, and Autoimmune Disorders Bones, Joints, Muscles