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Xeomin Injection for Stroke Recovery
The purpose of this study is to learn more about how the study drug, Xeomin, affects walking and balance after a stroke. We will use special devices to measure your movements. The study requires two visits to Carolinas Rehabilitation.
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Looking for Volunteers Interested in COVID-19 Related Studies
The purpose of this study is to make a list of people who want to volunteer for research and COVID-19 vaccine studies. This list is called the STRIVE registry. People on the list will be contacted about new studies they might join. Joining the list does not mean you have to join any future studies.
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Learning More About Using Sparsentan to Treat Glomerular Disease in Children
The purpose of this study is to find out how well the study drug, Sparsentan, works for treating kidney diseases in children. We also want to learn more about side effects that may be caused by the study drug.
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Comparing Two Study Drugs for Treatment of Vasculitis
Eosinophilic Granulomatosis with Polyangiitis is a disease that makes small blood vessels swell up in people with asthma. We want to see how two different study drugs, depemokimab and mepolizumab, work to treat this disease. We also want to learn about the possible side effects of each study drug.
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A Study of the Drug Batoclimab for Treatment of Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
Chronic inflammatory demyelinating polyneuropathy (CIDP) is an autoimmune disorder. The purpose of this study is to learn more about the study drug Batoclimab. We want to see if this study drug is safe and helps people with CIDP.
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Testing Cardiac Rehab for Amyloidosis
The study aims to find out if exercise programs can help people with this condition feel better.
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Learning More About Saliva and Dry Mouth
The purpose of this study is to find out what parts of saliva might cause people to feel like they have a dry mouth. By figuring this out, we can understand dry mouth better and treat it more effectively.
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Improving the Care and Health of Children, Adolescents, and Young Adults with Inflammatory Bowel Disease
The purpose of this study is to improve the care and health for children, teens, and young adults with IBD (Inflammatory Bowel Disease). We want to gather information from your regular care visits to help improve the care for patients with inflammatory bowel disease. For example, we could learn which type of medication works best for treating this disease.
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Can Atorvastatin Prevent Dementia, Disability or Heart Disease in Older Adults?
This study is also known as PREVENTABLE, and the goal is to learn if taking a statin could help older adults live well for longer by preventing dementia, disability, or heart disease. This study is one of the largest research studies in adults aged 75 and older. Our researchers make it easy for people to join the study by connecting with them at home and sending the medication directly to their homes. They also check participants' health records and call them once a year to keep track of their progress. For more information, visit the PREVENTABLE website at www.preventabletrial.org or contact the study contact below.
Study Topics
Finding Signs of Hearing Problems in Babies with Cytomegalovirus Infection Present at Birth
The purpose of this study is to learn more about tests that can be used to show how a baby's hearing will be affected if they have cytomegalovirus (CMV) infection present at birth.
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Infectious Diseases Screening and Prevention Children, Infants, Teen Health Ears, Nose, Throat, Mouth
A Study of the Drug ORIC-944 for Patients with Prostate Cancer
The purpose of this study is to learn more about the study drug ORIC-944. We want to see if this study drug is safe and useful to treat patients with prostate cancer that has spread to other areas of the body.
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Treating Hodgkin Lymphoma with Combination Immuno-oncology Therapy
The purpose of this study is to compare the effects, good and/or bad, of the study drugs, brentuximab vedotin and nivolumab (Bv-NIVO), to the usual treatment for people with Hodgkins Lymphoma to find out which is better.
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Treating Neuroblastoma in Young People with Naxitamab
The purpose of this study is to test the safety and effectiveness of adding a new drug called naxitamab to the usual treatment for a type of cancer called neuroblastoma.
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Cancer Cancer: Head, Neck Cancer: Thyroid, Other Glands Children, Infants, Teen Health
Using Pre-operative Stereotactic Radiosurgery to Treat Brain Cancer
This study is about finding the best way to treat cancer that has spread to the brain. The study will help doctors learn if doing SRS before surgery is better, the same, or worse than doing it after surgery. The study will also look at the risks and benefits of both approaches.
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A Study of the Drug Odronextamab for Follicular Lymphoma
Follicular lymphoma is a kind of non-Hodgkin lymphoma. This study wants to learn more about the drug Odronextamab for this disease. We want to see if the drug is safe and okay for patients who haven't been treated before. We also want to find out about any side effects the drug might cause.
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Studying a New Treatment Plan for Patients with Relapsed/Refractory Large B-cell Lymphoma or Grade IIIB Follicular Lymphoma
We are looking for volunteers with Grade IIIB Follicular or Relapsed/Refractory Diffuse Large B-cell Lymphoma. The purpose of this study is to see if we can reduce the chance of your cancer growing or spreading by adding more treatment to the usual therapy. We are doing this study to see if this new approach is better or worse than the usual approach for patients who are getting CAR T-cell therapy.
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Heart Device Safety and Medication Study
The purpose of this study is to learn more about a device to help patients with a heart condition called atrial fibrillation. We want to see how safe and useful different medications are after the device called WATCHMAN FLX Pro is placed in the heart. This device helps prevent blood clots and strokes in patients with atrial fibrillation.
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Testing Blood Counts in Different People
The purpose of this study is to learn more about different blood cell counts among people from Africa or the Middle East. People from these areas have fewer white blood cells because they don't have a certain red blood cell marker called the Duffy marker. This is normal and not harmful. The goal of this study is to find better blood count ranges for these people to improve their medical care.
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Testing New CAR T-Cell Therapy for Lymphoma
The purpose of this study is to learn more about the study drug, named PMB-CT01, also known as BAFFR-CAR T cells. We want to see if this study drug is safe and useful to treat people with B-cell Non-Hodgkin Lymphomas.
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Studying the Drug Glofitamab for Patients with Untreated Large B-Cell Lymphoma
The purpose of this study to learn more about the study drug Glofitamab. We want to see how safe and useful the study drug is for patients with large B-cell lymphoma who have not yet received treatment for it. We want to see how well this study drug works when used with other cancer drugs.
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