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Learning More About Treating Multiple Myeloma with Lower Doses of Isa-Pom-Dex
The purpose of this study is to find out how well the study drugs isatuximab, pomalidomide and dexamethasone (Isa-Pom-Dex) work when given at lower doses. Using Isa-Pom-Dex at lower doses may help patients get a better response from treatment. The lower doses may also cause fewer or less severe side effects.
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Learning More About Treating Asthma with Rocatinlimab
The purpose of this study is to learn more about how the study drug, rocatinlimab, works for people with moderate to severe asthma. We also want to learn more about side effects that may be caused by the study drug.
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Learning More About Budigalimab and ABBV-382 for Treatment of HIV
The purpose of this study is to see how well the study drugs, Budigalimab and ABBV-382, help the body control the HIV viral load after antiretroviral therapy has been stopped. We also want to learn more about side effects that may be caused by the study drugs.
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A Study of the Drug Durvalumab for Patients with High-Risk Liver Cancer
The purpose of this study is to learn more about the study drug Durvalumab when combined with classic chemotherapy. We want to find out if this approach is better or worse than the usual approach for your liver cancer.
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Learning More About the Long-Term Use of Sound to Reduce Stress in Healthcare Workers
The purpose of this study is to learn more about the long-term outcomes of Cereset technology. Cereset uses sound to promote brain relaxation and improved functioning. We want to find out how well additional sessions work over one year. Scalp sensors are used to monitor brain electrical activity, and computer software translates the activity into sounds. Those sounds are echoed back to participants via ear buds. The sounds may help your brain to achieve a more balanced brain pattern and reduce your symptoms.
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Learning More About Treating Advanced Non-small Cell Lung Cancer with Ramucirumab and Pembrolizumab
The purpose of this study is to find out if treating non-small cell lung cancer with the study drugs, ramucirumab and pembrolizumab, can help patients live longer. We want to find out if this approach is better than the usual approach to treating this type of lung cancer.
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Using the Study Drugs M1774 and Avelumab to Treat Merkel Cell Skin Cancer
The purpose of this study is to learn more about the study drug M1774. We want to see how well the study drug treats Merkel cell cancer when used alone and when combined with Avelumab. We want to find out if either approach is better or worse than the usual treatment.
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Testing a New Study Drug to Treat Polycythemia Vera
The purpose of this study is to test a new treatment for polycythemia vera. The study drug is called ISIS 702843. We want to find out how well the study drug works. We also want to learn more about the side effects of the study drug.
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Learning More About the Study Drug, XEN1101, for Treating Focal Onset Seizures
The purpose of this study is to find out if the study drug, XEN1101, can reduce seizure frequency. We also want to see if it is safe to use.
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Creating a Database to Learn More About Vercise Deep Brain Stimulation in Patients with Parkinsons Disease
Parkinson's disease affects nerve cells and causes tremors and muscle stiffness. It can also cause difficulty with speech and walking. The purpose of this study is to find out how brain stimulation effects patients with Parkinson's disease.
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Treating Asthma with AZD4604
The purpose of this study is to see how well the new study drug, AZD4604, works in treating asthma. We also want to learn more about the side effects of this drug.
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Learning More About the Study Drug, XEN1101, for Treating Primary Generalized Tonic-Clonic Seizures
The purpose of this study is to find out if the study drug, XEN1101, can reduce seizures. We also want to see if it is safe to use.
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Promoting Emotional Well-Being in Young Adult Cancer Survivors
The purpose of this study is to learn more about wellness and quality of life among young adult cancer survivors. We hope to promote well-being and teach skills to help with coping and mood management.
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Learning More About Treating Plaque Psoriasis with Deucravacitinib
The purpose of this study is to find out how well the study drug, deucravacitinib, works for treating psoriasis on the palms, soles, and genital area. We also want to learn more about side effects that may be caused by the study drug.
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Treating Atrial Fibrillation with Pulsed Field Ablation
The purpose of this study is to learn more about a new atrial fibrillation treatment called pulsed field ablation. We want to find out how well the treatment works.
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Study of Decreasing Drinking in Heavy Alcohol Users
The purpose of this study is to see how a tool called transcranial magnetic stimulation (TMS) may change the brain's response to alcohol related pictures. TMS is a technique that does not require surgery or anesthesia. The treatment may help reduce alcohol cravings in people with alcohol use disorder.
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Learning More About Blood Tests to Determine if a Cancer Patient Will Respond to Treatment
Not all patients treated with immune checkpoint inhibitors respond with tumor shrinkage. Many patients have serious side effects. The purpose of this study is to develop blood tests that can help determine if patients will respond to treatment and develop side effects.
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Treating Skin Lesions Caused by Colorectal Cancer Treatment
The purpose of this study is to learn more about the study drug, LUT014. We want to see how well it treats acneiform lesions.
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Testing the Addition of a New Drug, Daratumumab/rHuPH20, to the Usual Treatment for Multiple Myeloma
The purpose of this study is to see how well adding the drug, daratumumab/rHuPH20, to the usual treatment works for treating multiple myeloma. We want to find out if adding the drug could help patients live longer after stem cell transplant.
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Treating Ovarian Cancer with Luveltamab Tazevibulin
The purpose of this study is to find the best dose of the study drug, luveltamab tazevibulin, for treating ovarian cancer. We also want to learn about any side effects that may be caused by the study drug.
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