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Understanding Headaches Related to Having Large Breasts
Women can experience a number of symptoms related to having large breasts. Headache is one of those symptoms. Some women decide to have breast reduction surgery to help with the symptoms. The purpose of this study is to better understand the headaches had by women who have decided to have breast reduction surgery.
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Using Anifrolumab to Treat Lupus Nephritis
The purpose of this study is to learn more about a new lupus nephritis treatment called Anifrolumab. We want to find out how well it works and what side effects it may have.
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Studying the Medicine Apalutamide for Prostate Cancer After Surgery
The purpose of this study is to see if adding the medicine apalutamideo to your regular prostate cancer treatment can help stop the cancer from spreading for a longer time. We want to find out if this new way works better or worse than the usual treatment.
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Testing the Study Drug STP0404 for Treatment of HIV-1
The purpose of this study is to find out if the study drug, STP0404, decreases the amount of HIV virus in your body. We also want to learn more about the possible side effects of the study drug.
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Study of Non-Invasive Therapy for Female Patients with Interstitial Cystitis/Bladder Pain Syndrome
The purpose of this study is to see how well a non-invasive therapy works to treat interstitial cystitis/bladder pain syndrome. The therapy uses a device that sends magnetic waves into the body which may help the body better heal itself. We want to find out if the study therapy can reduce pelvic pain and urinary symptoms.
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Learning More About Adding TRC102 to the Usual Non-Small Cell Lung Cancer Treatment
The purpose of this study is to learn more about the study drug, TRC102. We want to see how it can affect Stage III lung cancer. TRC102 will be added to the usual treatment. The addition of TRC102 to the usual treatment could stabilize your cancer and lengthen the time you can live. This study will help the us find out if this approach is better than the usual approach.
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Treating Multiple Myeloma with Study Drug ABBV-383
The purpose of this study is to see how the study drug, ABBV-383, affects patients with multiple myeloma that has returned or been difficult to treat. Some volunteers will get increasing doses of the study drug. We want to see if the increasing doses can reduce a side effect known as cytokine release syndrome.
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Study of Quick Start Durvalumab for Treating Stage III Non-Small Cell Lung Cancer
Durvalumab is usually started 30 days or more after radiation treatment. The purpose of this study is to find out if it is possible to start Durvalumab within 14 days after radiation treatment. We want to see how the quick start affects you and your cancer.
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Testing RINVOQ for the Treatment of Adults with Lupus
The purpose of this study is to find out how well the study drug RINVOQ works for treating adults with systemic lupus erythematosus. We also want to find out how safe the study drug is for patients. RINVOQ is an FDA approved medication for other conditions.
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Testing the Combination of Abemaciclib and Olaparib for Treatment of Ovarian Cancer
The purpose of this study is to learn more about using abemaciclib and olaparib to treat ovarian cancer that has returned. This study tests different doses of the drugs to find the highest dose that is safe and well tolerated. We also want to see what side effects may occur.
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Treating Early Alzheimer's Disease with the Study Drug CT1812
The purpose of this study is to find out if the study drug, CT1812, can slow memory decline. We want to see how well it works for people with mild memory decline due to Alzheimer's disease and dementia.
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Comparing Two Surgical Procedures to Reduce the Risk of Ovarian Cancer
The purpose of this study is to compare two different surgeries to reduce the risk of ovarian cancer. The study will look at the process used to decide which surgery is best for the patient. It will also look at symptoms that occur after removal of the ovaries.
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Collecting Data from Study Volunteers with Pulmonary Fibrosis and Fibrosing Interstitial Lung Disease
The purpose of this registry is to collect data to be used for future research on pulmonary fibrosis and other conditions that cause scarring in the lungs. This is not a treatment study. We will collect information from you through interviews, questionnaires, and medical records. Blood draw will be required around every six months. Your information will be collected for at least 3 years.
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Study of Memory Loss in the African-American Population
The purpose of this study is to better understand what causes memory loss in African Americans. We hope this type of research will result in improved diagnosis, better treatment and possibly prevention.
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Studying Camizestrant for Breast Cancer Hormone Treatment
The purpose of this study is to learn more about the medicine camizestrant. We want to see how well the medicine works at stopping the cancer from coming back compared to the usual treatment.
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Learning More About the Medicine XEN1101 for Treating Seizures
The purpose of this study is to find out if the study medicine, XEN1101, can safely reduce seizures.
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How Brain Activity Relates to Your Ability to Shift Attention in Response to Images
The purpose of this study is to look at how brain activity is related to your ability to shift attention when visual cues change. You will be asked to view specified images while receiving an MRI scan.
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Causes of Obesity and Weight Loss
The purpose of this study is to gather data to help learn more about the causes of obesity. We also want to learn more about the things that can affect weight loss.
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Comparing the Drugs Aspirin and Apixaban to See How Well They Work at Preventing Stroke or Death
The purpose of this study is to look at the how the drugs apixaban and aspirin effect patients with irregular heartbeat and recent brain bleeding. We also want to find out which is better at preventing future strokes and death.
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