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Study to Better Understand Drug Induced Liver Injury
The purpose of this study is to try to understand why some people have liver injury after taking certain drugs or supplements. This is not a treatment study.
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A Study of the Drug ABBV-383 for Patients with Multiple Myeloma
The purpose of this study is to learn more about the study drug ABBV-383 for patients with multiple myeloma that has returned or has not responded to treatment. We want to find the best dose and learn about the safety and effects of the study drug.
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Study of Inherited Kidney Disease
The purpose of this study is to understand the experiences of people with a special type of inherited kidney disease. Taking part in this research will involve one 60-minute interview.
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Treating Recurrent Urethral Stricture with Tissue Engineered Urethral Construct
The urethra is a thin tube-like structure that allows urine to leave your bladder. Urethral stricture is a narrowing of the urethra that affects the flow of urine out of your bladder. The purpose of this study is to find out if an engineered urethra made from your own cells can be surgically implanted safely. We also want to find out if the implanted urethra helps improve urinating. The new urethral segment will be created using cells from your bladder, which are the same cells that make up your urethra.
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Internet-Based Program to Help Cancer Survivors Manage Pain
The purpose of this study is to learn more about an internet-based pain program combined with pain education. We want to see if the pain program and education can help reduce pain and improve impact on daily activities. We also want to see if this approach is better or worse than the usual approach.
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Can Atorvastatin Prevent Dementia, Disability or Heart Disease in Older Adults
This purpose of this study is to find out if a drug called atorvastatin can help older adults live well for longer by preventing dementia, disability or heart disease.
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Study to Find Out How Well Inebilizumab Works for Treating Brain Inflammation
The purpose of this study is to find out how well the study drug, Inebilizumab, works for people newly diagnosed with anti-NMDAR encephalitis. Anti-NMDAR is brain inflammation caused by antibodies.
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Low Muscle Mass and its Role in Side Effects from Colorectal Cancer Treatment in Older Adults
The purpose of this study is to find out if low muscle mass plays a role in side effects from colorectal cancer treatment.
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Collecting Blood and Tissue Samples from Patients with Blood Cancer (myeloproliferative neoplasms)
The goal of this study is to gather blood and tissue samples from patients with a type of blood cancer (myeloproliferative neoplasms). The samples will be used to help find new approaches to treatment.
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Online Learning Tool to Help People with Migraines
The purpose of this study is to see how well an online learning tool works for people with migraine. We need feedback to help ensure this learning tool is usable for people with migraine.
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Treating Head and Neck Cancer with Cetuximab
The purpose of this study is to see how well the drug Cetuximab works for treating head/neck cancer that stopped responding to treatment. It is possible that Cetuximab may work better when given in patients who have already had immunotherapy.
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The HEALEY Trial: Learning More About Different Treatments for ALS
The purpose of this study is to learn more about multiple treatments for amyotrophic lateral sclerosis (ALS). We want to find out if different treatments have an effect on ALS. We also want to find out if these treatments are safe to take without causing too many side effects.
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Looking at the Connection Between Endometriosis and Pregnancy Loss
The purpose of this study is to understand why some women repeatedly lose pregnancies. This study will look at tissue and blood samples from women with unexplained recurrent pregnancy loss.
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Studying a New CAR T Treatment for Multiple Myeloma
The purpose of this study is to learn more about a new treatment called arlo‑cel for people with multiple myeloma. The study will compare this new treatment to standard cancer medicines to see which works better and is safer. This study is for volunteers with multiple myeloma whose cancer came back or did not improve after other treatments.
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Concussion Symptoms in Young People Ages 11-17
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Comparing Two Different Methods of Surgery to Treat Osteosarcoma that Has Spread to the Lungs
The purpose of this study is to compare two different surgery methods for people with osteosarcoma that has spread to the lung. We want to find out which surgery method is better. One method is called open thoracic surgery. It is done through a single large cut between the ribs, opens the chest, and removes the cancer. The other method is called thoracoscopy. It is done through several small incisions and uses a small camera to help with removing the cancer. Both methods are considered standard treatment.
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Comparing Medicines for Newly Diagnosed Multiple Myeloma
The purpose of this study is to learn which of two medicines works better for people with a newly diagnosed blood cancer called multiple myeloma. We will see how iberdomide and lenalidomide help after a stem cell transplant and how they affect health and daily life.
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Studying a New Cell Therapy for People With Multiple Myeloma
The purpose of this study is to learn more about a new treatment made from a person's own immune cells. Our researchers want to see if this treatment can be used to treat multiple myeloma that has come back or stopped responding to treatment. The study compares this new treatment to standard treatments doctors already use. Researchers want to see which treatment works better and is safer for patients.
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Learning More About the Motivation to Continue a Treatment Regimen
The purpose of this study is to learn more about a new treatment made from a person's own immune cells. Our researchers want to see if this treatment can be used to treat multiple myeloma that has come back or stopped responding to treatment. The study compares this new treatment to standard treatments doctors already use. Researchers want to see which treatment works better and is safer for patients.
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Understanding Headaches Related to Having Large Breasts
Women can experience a number of symptoms related to having large breasts. Headache is one of those symptoms. Some women decide to have breast reduction surgery to help with the symptoms. The purpose of this study is to better understand the headaches had by women who have decided to have breast reduction surgery.
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