Studying the Drug MM-1-104 for People with Advanced or Spreading Cancer
The purpose of this study is to test a new drug called IMM-1-104. We want to see if this study drug is safe and useful for people with advanced or spreading cancer. The drug aims to stop cancer growth.
Study Topics
Testing the Study Drug Nivolumab for Patients with Multiple Myeloma
The goal of this study is to learn more about the study drug nivolumab. We want to find out if this drug is safe and helpful for people with multiple myeloma that has returned and isn't responding to other treatments. People who want to join this study must have already tried another drug called idecabtagene vicleucel.
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Studying Opioid Use After Cancer Surgery
The purpose of this study is to see how many pain pills are taken by cancer patients after surgery. We also want to see how patients get rid of leftover pills and how happy they are with their care. We are looking for volunteers who are already scheduled to have surgery to remove their bladder, kidney, or prostate because of cancer at Atrium Health Wake Forest Baptist Comprehensive Cancer Center.
Study Topics
Cancer Cancer: Kidney, Liver, Pancreas Cancer: Prostate Cancer: Urinary and Bladder
Testing Two Treatments for Prostate Cancer
The purpose of this study is to test two treatments for prostate cancer. We will compare Docetaxel alone to Docetaxel plus Radium-223. We want to see which treatment works better for men with advanced prostate cancer that has spread to bones. This study will help doctors find out which treatment helps patients live longer and feel better.
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Testing New Lymphoma Treatment Combinations
The purpose of this study is to test if different drug combinations are safe and work well for treating lymphoma. We want to see how your body processes these drugs and what effects they have on your cancer. We are testing two combinations: mosunetuzumab with CC-220 or CC-99282, and glofitamab with obinutuzumab and CC-99282. We will use different doses and schedules to see what works best.
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Comparing Different Treatments for Patients with Blood Cancer
The purpose of this study is to test two drug combinations for people with a type of blood cancer called Waldenström's Macroglobulinemia or Lymphoplasmacytic Lymphoma. We want to see if the new drug combination is safe and helps fight the cancer. The study is for volunteers who have not been treated for this cancer before.
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Studying a New Biomarker to Predict Breast Cancer Return
The goal of this study is to learn more about a new test called Oncodetect™. This test looks for signs of breast cancer in the blood. We want to see how well this test can find cancer coming back during and after treatments like surgery or radiation.
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Studying Factors for Successful Knee Injury Recovery in Athletes
The purpose of this research study is to find out what helps our patients recover well after a knee ligament injury and surgery. We are looking for healthy volunteers who participate in organized sports, have not hurt their knees before, and have not had surgery on their spine, hip, knee, ankle, or foot. If you volunteer for this study, you will need to come for a single visit lasting about 2 hours. We will contact you for up to 2 years to see if you get any injuries. This study will help researchers learn new information that may help others in the future.
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Comparing Home and Office-Based Care for Black Patients with High Blood Pressure
The purpose of this study is to compare two ways to improve care for non-Hispanic Black patients with high blood pressure. The first way provides care to patients electronically through phone and video visits. The second way is in person, at a doctor's office, the way someone might normally seek care. All patients will receive a cuff to self-monitor their blood pressure at home. We want to see which way would work better.
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Testing the Study Drug Xaluritamig for Prostate Cancer Patients
The purpose of this study is to learn more about the study drug Xaluritamig. We want to see if this study drug is safe and useful to treat patients with prostate cancer that has come back after their main treatment.
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Using Stereotactic Body Radiation Therapy to Treat Lung Cancer
The purpose of this study is to compare the usual treatment alone to using an additional treatment called Stereotactic Body Radiation Therapy plus the usual treatment.
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Using a Blood Test to Guide Colon Cancer Treatment
The purpose of this study is to find out if a blood test can help doctors choose the best kind of chemotherapy for people who had surgery for colon cancer. This blood test looks for something called ctDNA. ctDNA is tiny pieces of DNA from cancer cells that can be found in your blood. We want to see if using this blood test is better or worse than the usual way of deciding on treatment. We are looking for volunteers who have colon cancer and have been treated with surgery.
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Learning More about Eye Movement among ALS Patients
The purpose of this study is to learn how ALS, a disease that affects nerve cells, changes the way people move their eyes. What the researchers learn from this study could help make better tools for people with ALS. We also hope to help doctors track the disease more easily and learn more about how ALS develops. The researchers plan to share what they find so it can help people living with ALS, their caregivers, and other scientists.
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Using a Tracker to Learn More about Heart Rate Variability Changes and Cancer-Related Tiredness
This study aims to help people with pancreatic and breast cancer who feel very tired because of their illness. We will use an activity tracker to check changes in your heart rate variability and how well you sleep. We will also ask you to fill out surveys and keep a diary about your tiredness. The information we collect may help us understand how heart rate variability changes are related to cancer-related tiredness. This study will last around 1 month.
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Helping Families Make Kidney Treatment Choices
Nephrotic syndrome is a kidney problem that makes your body lose protein in your pee, causing swelling and other health issues. This study aims to help families choose the best treatments for this condition. We are looking for volunteers with children who have nephrotic syndrome. By sharing your experiences, you will help us find better ways to support families in making treatment decisions.
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Studying Extra Therapies People Use During Cancer Treatment
The purpose of this study to learn more about other ways people manage their cancer symptoms while they are getting treatment. These other ways include using things like cannabis (also called marijuana), vitamins or supplements, and doing activities like acupuncture or meditation. We want to find out if these methods help or hurt people compared to the usual care they get from their doctor.
Study Topics
Cancer Cancer: Breast Cancer: Colon, Rectum, Anus Cancer: Lung Cancer: Lymphoma Cancer: Skin
Studying Digoxin to Help Treat Brain Cancer
The purpose of this study is to learn more about a medicine called digoxin. We want to see if this medicine can help stop a type of brain cancer called medulloblastoma from getting worse. The goal is to learn if this treatment can help and to understand any side effects it may cause. We are looking for volunteers who have been diagnosed with medulloblastoma.
Study Topics
Cancer Cancer: Brain, Nervous System, Spinal Cord Cancer: Rare Cancers Children, Infants, Teen Health
Testing the Study Drug Olvi-Vec for Ovarian Cancer that Resists Treatment
The purpose of this study is to collect information on how Medtronic devices work over time. We want to improve the safety and performance of these devices. The study is for volunteers who has or is intended to receive or be treated with, an eligible Medtronic product. The study team will provide more information.
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Testing the Study Drug Olvi-Vec for Ovarian Cancer that Resists Treatment
The purpose of this study is to learn about the drug Olvi-Vec. We want to see if it is safe and helpful for treating ovarian, fallopian tube, or peritoneal cancer that did not get better with a type of treatment called platinum-based chemotherapy.
Study Topics