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Online Learning Tool to Help People with Migraines
The purpose of this study is to see how well an online learning tool works for people with migraine. We need feedback to help ensure this learning tool is usable for people with migraine.
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Study of a Web-based Tool to Diagnose Parkinson's Disease
The purpose of this study is to see how well a web-based software tool called Automated Imaging Differentiation of Parkinsonism works. The software will provide accurate diagnosis between Parkinson's disease, multiple system atrophy parkinsonian, and progressive supranuclear palsy.
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Using Belumosudil to Treat Chronic Graft Versus Host Disease
The purpose of this study is to learn more about the study drug Belumosudil. We want to see how well the study drug works for treating chronic graft versus host disease. We also want to learn more about the side effects that may be caused by the study drug.
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Treatment of Acute Lymphoblastic Leukemia with Inotuzumab Ozogamicin and Blinatumomab
The purpose of this study is to find out if the study drugs, Inotuzumab Ozogamicin and Blinatumomab, can improve the chance of your leukemia going away. We also want to find out if we the study drugs can lower the chance of your leukemia coming back. We want to find out if this approach is better or worse than the usual approach.
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Medical Problems After Treatment for Childhood Cancer
One goal of this study is to look at how other medical problems develop after treatment for childhood cancer. We want to see how these problems relate to the type of cancer, stage of cancer and treatment. We also want to compare cancer patients with these problems to other cancer patients with the same diagnosis who do not have problems after treatment.
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Treating Uncontrolled Seizures with the Study Drug NRTX-1001
The purpose of this study is to learn more about treating uncontrolled seizures with the study drug NRTX-1001. We want to see how the study drug works and find out what side effects may be caused.
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Learning More About How the Brain Changes While Being Treated for Depression
The purpose of this research is to study how the human brain processes information and how people make decisions. Taking part in this study includes up to three visits. Each visit will last about 3-4 hours.
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A Study of a New Method To Diagnose Premature Rupture for Pregnant Women
The purpose of this study is to find a new way to diagnose premature rupture of membranes (PROM) in a non-invasive way by detecting ampicillin in amniotic fluid (the fluid surrounding the fetus in the womb) leaked to the vagina when the amniotic membranes are ruptured.
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Learning More About Factors that May Affect Correct Inhaler Techniques
The purpose of this study is to learn more about factors that may affect correct technique with hand-held inhalers.
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How Salt Affects Blood Pressure in Young Adults Who Were Born Prematurely
The purpose of this study is to learn about how salt in the diet affects blood pressure in young adults who were born prematurely. We also want to find out if the medication, allopurinol, can change how salt in the diet affects blood pressure.
Study Topics
Healthy Volunteers Heart Health Kidneys, Liver, Pancreas Children, Infants, Teen Health
Treating B-Acute Lymphoblastic Leukemia (B-ALL) in Children and Young Adults with Inotuzumab Ozogamicin
Lymphoblastic Leukemia (B-ALL) is a cancer of the white blood cells. The purpose of this study is to find out how well the study drug, Inotuzumab ozogamicin, works for children and young adults with B-ALL.
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Learning More About Treating Nonrelapsing Secondary Progressive Multiple Sclerosis with Frexalimab
The purpose of this study is to see if the study drug, Frexalimab, can keep multiple sclerosis from getting worse. We also want to learn more about the side effects that may be caused by the study drug.
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Learning More About Rheumatoid Arthritis Treatments
The purpose of this study is to learn more about rheumatoid arthritis. We want to learn more about rheumatoid arthritis treatments and how well they work. The information collected in this study may help improve the care of people with rheumatoid arthritis. This is not a treatment study.
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Testing the Genetics of People with Lung Cancer
The purpose of this study is to test surgically removed lung cancer tumors for certain genetic changes. This information will be used to determine which treatment a patient receives. We want to learn more about how certain medications may target tumors with certain genetic changes. We also want to learn more about why treatments may work better or stop working in some patients.
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Learning More About Treating Eosinophilic Asthma with Dexpramipexole
The purpose of this study is to find out how well the study drug, dexpramipexole, works for treating eosinophilic asthma. We also want to learn more about side effects that may be caused by the study drug.
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Study Combining Chemotherapy with the Drugs Atezolizumab and Bevacizumab in Treatment of Colon Cancer
This study combines the study drug, Atezolizumab, with chemotherapy. We want to see how well this combination works for treating colorectal cancer. We also want to learn more about the side effects of this combination.
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Learning More About Treating Severely High Triglyceride Levels with Pegozafermin
The purpose of this study is to see how well the study drug, Pegozafermin, helps with severely high triglyceride levels. We also want to learn more about side effects that may be caused by the study drug.
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A Study of Methotrexate in People with Breast, Brain, or Spinal Cord Cancer
Methotrexate is a type of chemotherapy drug. The purpose of this study is to find out how well high-dose Methotrexate works for treating breast cancer that has spread to the membrane that cover the brain and spinal cord. We also want to find out what the side effects of this treatment may be. Methotrexate will be given to study volunteers in the hospital every 2 weeks until there is evidence that the cancer is growing.
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Collecting Blood and Tissue Samples from Patients with Blood Cancer (myeloproliferative neoplasms)
The goal of this study is to gather blood and tissue samples from patients with a type of blood cancer (myeloproliferative neoplasms). The samples will be used to help find new approaches to treatment.
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Testing the Study Drug CIN-102 for Diabetic Gastroparesis Treatment
Diabetic gastroparesis is a condition where the stomach takes too long to empty its contents. The purpose of this study is to learn more about the study drug CIN-102 for treatment of this condition. We want to test the safety and possible side effects of this study drug.
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