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Study to Find Out How Well Inebilizumab Works for Treating Brain Inflammation
The purpose of this study is to find out how well the study drug, Inebilizumab, works for people newly diagnosed with anti-NMDAR encephalitis. Anti-NMDAR is brain inflammation caused by antibodies.
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Low Muscle Mass and its Role in Side Effects from Colorectal Cancer Treatment in Older Adults
The purpose of this study is to find out if low muscle mass plays a role in side effects from colorectal cancer treatment.
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Online Learning Tool to Help People with Migraines
The purpose of this study is to see how well an online learning tool works for people with migraine. We need feedback to help ensure this learning tool is usable for people with migraine.
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Online Learning Tool to Help People with Migraines
The goal of this study is to gather blood and tissue samples from patients with a type of blood cancer (myeloproliferative neoplasms). The samples will be used to help find new approaches to treatment.
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Treating Head and Neck Cancer with Cetuximab
The purpose of this study is to see how well the drug Cetuximab works for treating head/neck cancer that stopped responding to treatment. It is possible that Cetuximab may work better when given in patients who have already had immunotherapy.
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The HEALEY Trial: Learning More About Different Treatments for ALS
The purpose of this study is to learn more about multiple treatments for amyotrophic lateral sclerosis (ALS). We want to find out if different treatments have an effect on ALS. We also want to find out if these treatments are safe to take without causing too many side effects.
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Looking at the Connection Between Endometriosis and Pregnancy Loss
The purpose of this study is to understand why some women repeatedly lose pregnancies. This study will look at tissue and blood samples from women with unexplained recurrent pregnancy loss.
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Concussion Symptoms in Young People Ages 11-17
The purpose of this study is to learn more about concussion symptoms in young people ages 11 to 17. This may help us develop future treatments.
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Comparing Two Different Methods of Surgery to Treat Osteosarcoma that Has Spread to the Lungs
The purpose of this study is to compare two different surgery methods for people with osteosarcoma that has spread to the lung. We want to find out which surgery method is better. One method is called open thoracic surgery. It is done through a single large cut between the ribs, opens the chest, and removes the cancer. The other method is called thoracoscopy. It is done through several small incisions and uses a small camera to help with removing the cancer. Both methods are considered standard treatment.
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Studying a New CAR T Treatment for Multiple Myeloma
The purpose of this study is to learn more about a new treatment called arlo‑cel for people with multiple myeloma. The study will compare this new treatment to standard cancer medicines to see which works better and is safer. This study is for volunteers with multiple myeloma whose cancer came back or did not improve after other treatments.
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Learning More About the Motivation to Continue a Treatment Regimen
The purpose of this study is to learn more about the opinions and preferences of older adults living with chronic conditions such as human immunodeficiency virus (HIV), diabetes, COPD and other chronic health conditions. We want to learn more about their experience with medication regimens.
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Comparing Medicines for Newly Diagnosed Multiple Myeloma
Women can experience a number of symptoms related to having large breasts. Headache is one of those symptoms. Some women decide to have breast reduction surgery to help with the symptoms. The purpose of this study is to better understand the headaches had by women who have decided to have breast reduction surgery.
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Understanding Headaches Related to Having Large Breasts
Women can experience a number of symptoms related to having large breasts. Headache is one of those symptoms. Some women decide to have breast reduction surgery to help with the symptoms. The purpose of this study is to better understand the headaches had by women who have decided to have breast reduction surgery.
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Studying a New Cell Therapy for People With Multiple Myeloma
The purpose of this study is to learn more about a new treatment made from a person's own immune cells. Our researchers want to see if this treatment can be used to treat multiple myeloma that has come back or stopped responding to treatment. The study compares this new treatment to standard treatments doctors already use. Researchers want to see which treatment works better and is safer for patients.
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Using Anifrolumab to Treat Lupus Nephritis
The purpose of this study is to learn more about a new lupus nephritis treatment called Anifrolumab. We want to find out how well it works and what side effects it may have.
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Understanding Needs of Young People With Cancer
This study aims to learn what young people with cancer need most while getting care and after treatment. We want to understand what topics they want more education and support about, such as health, emotions, and daily life. What we learn will help improve programs and services for young people with cancer. We are looking for volunteers who were between 15 and 39 years old when they were diagnosed with cancer and are currently getting cancer treatment or have had cancer treatment in the past.
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Testing the Study Drug STP0404 for Treatment of HIV-1
The purpose of this study is to find out if the study drug, STP0404, decreases the amount of HIV virus in your body. We also want to learn more about the possible side effects of the study drug.
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Studying a New Implant for Stress Urinary Incontinence
Stress Urinary Incontinence (SUI) is a common type of urine leakage among men. The purpose of this study is to test how safe and how well a new implanted device works for this condition. The device is designed to help men who leak urine during activities like coughing or exercising. Our researchers want to see if it can reduce urine leaks and improve daily life. We are looking for male volunteers who have been diagnosed with SUI for at least 6 months.
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Study of Non-Invasive Therapy for Female Patients with Interstitial Cystitis/Bladder Pain Syndrome
The purpose of this study is to see how well a non-invasive therapy works to treat interstitial cystitis/bladder pain syndrome. The therapy uses a device that sends magnetic waves into the body which may help the body better heal itself. We want to find out if the study therapy can reduce pelvic pain and urinary symptoms.
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Studying a New Medicine to Help People With ATTR Heart Disease
ATTR amyloidosis is a disease where a protein called transthyretin builds up in the body and causes problems, especially in the heart and nerves. The purpose of this study is to learn more about a new medicine called nucresiran to help people with this disease.
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