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A Study of a Vaccine to Help Prevent C. diff
Clostridioides difficile (C. diff) is a germ that can spread from person to person. It can cause very bad diarrhea and, in serious cases, can be life threatening. This study looks at whether a new vaccine can help prevent C. diff diarrhea or make the illness less severe, reduce doctor visits, or lower the need for antibiotics in adults age 65 and older.
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Studying a New HIV Medicine for Adults
The purpose of this study is to learn more about a new HIV medicine called GS-0415 in people whose HIV is well controlled with their current HIV treatment. Researchers want to learn if the medicine is safe, how the body responds to it, and how it moves through the body.
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Studying a New COVID-19 Vaccine among Patients who have Received a Cell Therapy
The purpose of this study is to see if a new vaccine called GEO-CM04S1can help people who have received a cell therapy build protection from COVID-19. We want to compare this new vaccine to the current COVID-19 vaccines and see which one will work better.
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Learning More About the Motivation to Continue a Treatment Regimen
The purpose of this study is to learn more about the opinions and preferences of older adults living with chronic conditions such as human immunodeficiency virus (HIV), diabetes, COPD and other chronic health conditions. We want to learn more about their experience with medication regimens.
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Studying a New Hepatitis B Blood Test
The purpose of this study is to find out how well a new rapid blood test can detect hepatitis B infection. Researchers will compare the test results to standard laboratory testing to see how accurate and easy the test is to use in healthcare settings. This study is for volunteers who are experiencing signs or symptoms that may be related to hepatitis and have a history of factors that may increase the chance of hepatitis B infection.
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Studying a New Treatment Schedule for HIV
The purpose of this study is to learn more about a new treatment for HIV called Cabotegravir. Researchers want to see if the new HIV shots given every 4 months work as well as the current HIV shots given every 2 months. The goal is to see if people with well-controlled HIV can keep the virus under control with fewer injections each year. This study is for volunteers living with HIV who have been taking HIV treatment for at least 6 months.
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Studying a New Treatment for Virus After Transplant
Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease (EBV/PTLD) is a virus that can happen after receiving a solid organ transplant or allogenic cell transplant. The purpose of this study is to learn more about a new treatment called tabelecleucel. We want to see how well this treatment works for patients with this virus who did not get better with a treatment called rituximab or rituximab plus chemotherapy.
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