Search Studies
Treating Uncontrolled Seizures with the Study Drug NRTX-1001
The purpose of this study is to learn more about treating uncontrolled seizures with the study drug NRTX-1001. We want to see how the study drug works and find out what side effects may be caused.
Study Topics
Learning More About Treating Nonrelapsing Secondary Progressive Multiple Sclerosis with Frexalimab
The purpose of this study is to see if the study drug, Frexalimab, can keep multiple sclerosis from getting worse. We also want to learn more about the side effects that may be caused by the study drug.
Study Topics
Study of COVID19 Infections Using At-Home Rapid Diagnostic Test Kits and Online Data Gathering
The purpose of this study is to collect information about our community's COVID-19 exposures, symptoms, and health care visits due to the virus.
Study Topics
Learning More about the Study Drug Lepodisiran to Reduce Heart Attacks and Stroke
The purpose of this study is to learn more about the study drug lepodisiran. We want to see if the study drug can reduce problems like heart attack or stroke in adults with elevated lipoprotein (a). We also want to learn more about the side effects that may be caused by the study drug.
Study Topics
Learning More About How Gut Micro-organisms Play a Role in Prostate Cancer
The purpose of this study is to find out how the gut micro-organisms may affect prostate cancer that spreads to the bone. In this study, the methods required to study these gut-bone interactions will be developed and tested.
Study Topics
A Study of Telehealth to Treat Children with Medical Complexity
The purpose of this study is to learn more about using telehealth visits for children with medical complexity. We want to find out if telehealth visits can improve the health of children with chronic health problems.
Study Topics
Learning More About Treating Solid Tumors with SGN-EGFRd2
The purpose of this study is to find out how well the study drug, SGN-EGFRd2, works for treating solid tumor cancers. We also want to find out what side effects may be caused by the study drug.
Study Topics
Learning More About a New Approach to Treating Ductal Carcinoma In Situ
Some ductal carcinoma in situ (breast cancer) is lower risk than others for turning into invasive cancer. The purpose of this study is to try and figure out which ductal carcinoma in situ is low risk. It's possible low-risk breast cancer can be treated with only hormone therapy pills and avoid surgery.
Study Topics
Learning More About the Use of Frexalimab for Treating Relapsing Multiple Sclerosis
The purpose of this study is to see how well the study drug, frexalimab, works for treating relapsing multiple sclerosis. We also want to learn more about possible side effects of the study drug.
Study Topics
Treating Focal Onset Epilepsy with Study Drug BHV-7000
The purpose of this study is to find out how well the study drug, BHV-7000, works for treating focal seizures. We also want to learn more about side effects that may be caused by the study drug.
Study Topics
A Study of Methotrexate in People with Breast, Brain, or Spinal Cord Cancer
Methotrexate is a type of chemotherapy drug. The purpose of this study is to find out how well high-dose Methotrexate works for treating breast cancer that has spread to the membrane that cover the brain and spinal cord. We also want to find out what the side effects of this treatment may be. Methotrexate will be given to study volunteers in the hospital every 2 weeks until there is evidence that the cancer is growing.
Study Topics
Understanding How Chemotherapy Treatment Before Surgery Impacts Recovery
The purpose of this study is to learn how chemotherapy treatment before surgery affects your body and brain. Some people get chemotherapy before surgery, and some get it after. By looking at changes in health, doctors hope to understand how chemotherapy before surgery helps people feel better and recover faster. We are looking for volunteers who have recently been diagnosed with a gynecological cancer (ovarian, peritoneal, fallopian tube, or endometrial) and are planning to receive chemotherapy treatment followed by surgery afterwards.
Study Topics
Finding Muscle Changes in Myotonic Dystrophy Patients
Myotonic dystrophy (DM) is a disease that causes muscles to weaken and waste away. The purpose of this study is to find the best ways to measure muscle weakness and changes in patients with DM using MRI scans. Understanding these changes will help plan future studies to track the disease and test new treatments. We are seeking healthy volunteers as well as volunteers who have been diagnosed with myotonic dystrophy.
Study Topics
Using Body Fat Images to Assess Health
The purpose of this study is to see if we can use medical images of fat throughout the body to assess your health status.
Study Topics
Aging Healthy Volunteers Heart Health Weight, Metabolism, Nutrition
A Study of the Drug Volrustomig for Head and Neck Cancer Treatment
The purpose of this study is to see if we can use medical images of fat throughout the body to assess your health status.
Study Topics
Comparing Methods to Test for Anal Cancer and HPV
The purpose of this study is to compare three methods of collecting anal swabs for testing HPV and anal cancer. These methods include patients collecting swabs at home, patients collecting swabs in a clinic, and healthcare workers collecting swabs. The goal is to determine if all three methods provide the same results. We are looking for volunteers who are at high risk for anal cancer and meet the screening criteria for anal dysplasia.
Study Topics
Studying a New Way to Prevent Blood Clots During Medical Procedures
The goal of this study is to help people who need medical procedures where their blood goes outside their body, like during dialysis or heart surgery. We want to find a way to stop blood clots during these procedures. This study will help us learn how to prevent clots and make these procedures safer. We are looking for healthy volunteers, both adults and children, who are 17-70 years old and weigh over 110 pounds.
Study Topics
New Migraine Medicine for Teens
The purpose of this study is to learn more about a new medicine called Rimegepant to help teenagers with chronic migraine. We want to see if this medicine is safe and useful to prevent chronic migraine.
Study Topics
Studying a New Medicine to Help People with COPD
The goal of this study is to see if a new medicine called lunsekimig can help people with COPD feel better. It will look at how well the medicine works for people who still have breathing problems even though they are already getting treatment. The study will also check if the medicine causes any side effects.
Study Topics
Studying the Medicine VX-670 for Myotonic Dystrophy Type 1
Myotonic Dystrophy Type 1 is a disease that makes muscles weak and hard to relax, and it can also affect other parts of the body like the heart and stomach. The purpose of this study is to see if a new medicine is safe and works well for people with this disease. Our researchers will see if the medicine can help with muscle problems and check for any side effects over two years.
Study Topics
Movement Disorder Neurology Disorders Rare Disease Bones, Joints, Muscles