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Brain Changes after Radiation Treatment for Glioma
Glioma is a type of brain cancer. The purpose of this study is to see if we can predict how brain function will change after radiation treatment for glioma. We will be doing PET scans and blood tests with glioma patients. A PET scan is a type of test that gives us images of your brain and can help detect certain diseases.
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A Study of the Drug LP-10 for Patients with Oral Lichen Planus
Oral Lichen Planus is a long-term condition that causes swelling and irritation inside your mouth. The purpose of this study is to learn more about the study drug LP-10 for patients with oral lichen planus. We want to see if this study drug is safe and works well for treating this condition.
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Study of Batoclimab for Treating Active Thyroid Eye Disease
The purpose of this study is to see if batoclimab helps people with active moderate-to-severe thyroid eye disease. We also want to find out if batoclimab is safe.
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Osteoarthritis Prevention Study
Exercise and diet have been shown to help with the treatment of osteoarthritis. The purpose of this study is to find out if exercise and diet prevents osteoarthritis.
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Arthritis, Lupus, and Autoimmune Disorders Weight, Metabolism, Nutrition
A Study of the Drug Efruxifermin for Treating Liver Diseases and Scarring of the Liver
Non-alcoholic steatohepatitis and metabolic dysfunction-associated steatohepatitis are types of fatty liver disease that cause scarring of the liver. We want to learn more about the safety and effects when using the study drug Efruxifermin to treat these diseases.
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Treating Endometrial Cancer by Targeting HER2 Proteins
Endometrial cancer is a type of cancer in the uterus. This study is being done to find out if we can lower the chance of endometrial cancer coming back by using drugs that target HER2 proteins. Those drugs will be given in addition to the usual chemo drugs.
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Learning More About Myasthenia Gravis
Myasthenia gravis causes a breakdown in the normal communication between nerves and muscles. This causes weakness and fatigued muscles. The purpose of this study is to help researchers learn more about myasthenia gravis. We will be collecting data and storing blood samples for future research. This is not a treatment study.
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Cell Treatment for Urinary Incontinence
Stress urinary incontinence (SUI) is an accidental loss of urine due to laughing, coughing, or sneezing. The purpose of this study is to learn more about using a type of cell treatment to help women with SUI. This study focuses on women with SUI that did not get better after surgical treatment.
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Understanding Headaches Related to Having Large Breasts
Women can experience a number of symptoms related to having large breasts. Headache is one of those symptoms. Some women decide to have breast reduction surgery to help with the symptoms. The purpose of this study is to better understand the headaches had by women who have decided to have breast reduction surgery.
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What Traits Do Patients Consider When Choosing a Primary Doctor
The purpose of this study is to learn why and how patients select their primary doctor.
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Learning More About the Neuroguard IEP Direct System for Treatment of Carotid Artery Narrowing
The purpose of this study is to learn more about a new study device called the Neuroguard IEP Direct System to treat patients with narrowed arteries in their neck that supply blood to their brain. The treatment involves making a small cut on one side of your neck to place the device.
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Finding Out How Well Adding a Third Medication to Treatment Works for Treating Advanced Rectal Cancer
The purpose of this study is to find out if we can increase the likelihood of your tumor disappearing by adding a third drug to the usual treatment. We want to find out if this approach is better or worse than the usual approach.
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Learning More About Treating T-cell Lymphoma with the Study Drug Duvelisib or Azacitidine
The purpose of this study is to learn more about treating peripheral T-cell lymphoma with the study drug Duvelisib or Azacitidine. One of the study drugs will be given along with the usual treatment. We want to see how well the combination treatment works. We also want to learn more about possible side effects.
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Using Mavacamten to Treat Adolescents with Cardiomyopathy
Obstructive Hypertrophic Cardiomyopathy (HCM) is a heart condition that makes it hard for the heart to pump blood and may make a person feel weak and tired. The purpose of this study is to see if the study drug, mavacamten, helps young people with obstructive HCM.
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Learning More About the Effects of Very Low-Nicotine Cigarettes on the Heart
The purpose of this study is to learn more about the effects of very low-nicotine cigarettes on the heart.
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Heart Health Substance Use (Alcohol, Illegal Drugs, Tobacco)
Finding a Way to Predict Success or Failure of Treatment for Atopic Dermatitis and Psoriasis
There are a number of treatments for psoriasis and atopic dermatitis. This has created a need to find a way to figure out which treatment will work best for each patient. The goal of this study is to develop a test that can predict treatment success and/or failure. If you take part in this study, no changes will be made to your treatment for psoriasis or atopic dermatitis.
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A Study of the Drug Lutikizumab for Treatment of Ulcerative Colitis
The purpose of this study is to learn more about the study drug Lutikizumab. We want to see if this study drug is safe and effective for treatment of ulcerative colitis. We also want to compare this study drug to the current drug Adalimumab.
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Study of the Drug GS-8588 in People with HIV-1 Who are Virologically Suppressed on Antiretroviral Therapy
The purpose of this study is to find out how well the study drug GS-8588 is tolerated when given at different doses. We also want to find out how the body's immune system reacts to GS-8588.
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Finding Better Ways to Diagnose and Treat Leukemia in Children, Adolescents and Young Adults
The purpose of this study is to test bone marrow and blood from people with leukemia. We want to see if the leukemia has certain traits that could help the doctors decide what medicine might be best for you. This study will also collect information about your treatment for leukemia. We want to see how well it worked and find out if there were any long-term side effects.
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Using Special Eyeglasses to Detect Absence Seizures in Children
The purpose of this study is to learn more about a new type of eyeglasses. We want to find out if eyeglasses can tell if a child is having absence seizures or having attentional difficulties.
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