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Collecting Data from Hemophilia Patients
The purpose of this study is to collect data on a blood disorder called hemophilia. The data will be used to improve the care of patients.
Study Topics
Heart Health Cancer Cancer: Children, Teens Children, Infants, Teen Health
The Use of Muscle Fiber Fragments to Treat the Loss of Bladder Control in Women
The purpose of this study is to find out if injecting muscle fiber fragments into the bladder can treat bladder leakage in women. Taking part in this study will include seven study visits in a year.
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Studying New Treatments for Head and Neck Cancer Patients
The goal of this study is to find out more about a new treatment for people with head and neck cancer. We want to see if using a treatment called Petosemtamab along with another treatment called pembrolizumab can help stop the cancer from growing or spreading and make patients feel better. We are looking for volunteers who have head and neck cancer that has spread to other parts of their body or has not gotten better with other treatments. The study team will give more details.
Study Topics
Studying a New Asthma Medicine for Adults
The purpose of this study is to learn more about a new medicine for patients with uncontrolled asthma. We want to see if the medicine called AZD8630 is safe and works well when used with an inhaler. Findings from this study may help other patients with asthma and other lung conditions in the future.
Study Topics
Reducing Infection Risk in C-Section Deliveries
The goal of this study is to find a way to lower the chance of getting an infection after a C-section. We want to see if using two antibiotics instead of one before the C-section can help prevent infections like endometritis, wound infection, or sepsis. We are looking for volunteers who are at least 23 weeks pregnant and are planning to have a C-section.
Study Topics
Studying a New Medicine for Myelofibrosis
The purpose of this study is to learn more about a new medicine called Canakinumab. We want to see if it helps people with a rare bone marrow cancer called myelofibrosis. The medicine will be used along with another medicine that patients are already taking. The goal is to find out if this new medicine is safe and if it helps people feel better.
Study Topics
Studying a New Endometrial Cancer Medicine
The goal of this study is to learn about a new cancer medicine called Sacituzumab Govitecan. This medicine is for patients whose endometrial cancer has returned. We want to find out if this medicine can help patients live longer and slow down or stop their cancer from growing. We will compare this medicine to regular chemotherapy treatments like doxorubicin or paclitaxel.
Study Topics
Brain Changes after Radiation Treatment for Glioma
Glioma is a type of brain cancer. The purpose of this study is to see if we can predict how brain function will change after radiation treatment for glioma. We will be doing PET scans and blood tests with glioma patients. A PET scan is a type of test that gives us images of your brain and can help detect certain diseases.
Study Topics
The Osteoarthritis Prevention Study (TOPS)
Exercise and diet have been shown to help with the treatment of osteoarthritis. The purpose of this study is to find out if exercise and diet prevents osteoarthritis.
Study Topics
Arthritis, Lupus, and Autoimmune Disorders Weight, Metabolism, Nutrition
Finding a Way to Predict Success or Failure of Treatment for Atopic Dermatitis and Psoriasis
There are a number of treatments for psoriasis and atopic dermatitis. This has created a need to find a way to figure out which treatment will work best for each patient. The goal of this study is to develop a test that can predict treatment success and/or failure. If you take part in this study, no changes will be made to your treatment for psoriasis or atopic dermatitis.
Study Topics
A Study on Treating Tumors that Spread to the Brain and Came Back After Radiation
This study examines different treatments for people whose brain tumors come back after radiation treatment. All patients will have a biopsy first and results will impact following treatment:
Study Topics
Finding Ways to Improve Health for Older Adults with B-cell Non-Hodgkin Lymphoma or Multiple Myeloma
The purpose of this study is to see if we can decrease CAR-T therapy side effects. We also want to see if we can improve care in older adults with non-Hodgkin lymphoma or multiple myeloma. Pre-treatment assessments will be done to identify weaknesses and guide referrals for additional care if needed. We want to see if this approach will improve health for patients.
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Looking at How Estrogen Deprivation Affects Heart Function in Breast Cancer Patients
The purpose of this study is to learn more about how near complete estrogen deprivation therapy effects the heart in breast cancer patients. We want to understand if this therapy changes how the heart works.
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Using Muscle Fiber Fragment Injections to Treat Fecal Incontinence
The purpose of this study is to look at a new way to treat fecal incontinence. We want to know if injecting muscle fiber fragments into the muscle at the bottom of the anus can help with leaking stool.
Study Topics
Can Physical Activity Be Helpful for Lymphoma Patients During Treatment?
The purpose of this study is to find out if exercise or educational classes can be helpful for lymphoma patients. We want to know if exercise or classes can help patients keep their quality of life and ability to exercise. We also want to know if exercise or classes can help lymphoma patients with memory and heart health.
Study Topics
Learning More About Treating Systemic Lupus Erythematosus with Litifilimab
The purpose of this study is to find out if the study drug, Litifilimab, can improve symptoms of lupus. We want to see if the study drug can reduce disease activity and inflammation
Study Topics
Study to See How Well the Study Drug EPX-100 Works for Treating Dravet Syndrome
The purpose of this study is to see how well the study drug, EPX-100, works for treating Dravet syndrome. We also want to learn more about possible side effects.
Study Topics
Studying New Ways to Reduce Caregiver Stress
The purpose of this study is to see if listening to nature sounds and using a new technology called CR can help people who take care of loved ones feel less stressed. Taking care of someone can be stressful and affect your health. This study will test if CR can help reduce stress symptoms like anxiety, trouble sleeping, and changes in heart rate in a small group of people.
Study Topics
Healthy Volunteers Mental Health Neurology Disorders Sleep Brain and Memory
Treating Prostate Cancer with Omeprazole and Chemotherapy
The purpose of this study is to find out how Omeprazole may help treat prostate cancer. It will be given along with chemotherapy. Researchers believe Omeprazole may help the chemotherapy work.
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Study to Find Out if the Study Drug, LN145, Works Well for Treating Nonsmall Cell Lung Cancer
The purpose of this study is to find out if the study drug, LN145, works well for treating nonsmall cell lung cancer.
Study Topics