About This Study
Methotrexate is a type of chemotherapy drug. The purpose of this study is to find out how well high-dose Methotrexate works for treating breast cancer that has spread to the membrane that cover the brain and spinal cord. We also want to find out what the side effects of this treatment may be. Methotrexate will be given to study volunteers in the hospital every 2 weeks until there is evidence that the cancer is growing.
Have breast cancer that has spread to the membranes that cover your brain and spinal cord. Study team will discuss study details with you.
What Activities Are a Part of this Study?
- Informed Consent Review
- Use of Study Treatments or Placebo
- After Study Follow-Up Activities
- Review of Medical History
- Physical Examinations
- Phone Calls and/or Emails
- Study Visits and Consultations
- Laboratory and Imaging Tests
- Specimen Sample Collection
Age & Gender
- 18 - 100 years old
- All Genders
Language
- This study enrolls English and Spanish speakers
Additional Study Information
- No compensation provided
- Reimbursement offered
Study Locations
- Greater Winston-Salem, NC