Search Studies
Treating Ovarian Cancer with Avutometinib and Defactinib
The purpose of this study is to compare the combination of the study drugs, avutometinib and defactinib, to the usual treatment for a type of cancer called low grade serous ovarian cancer.
Study Topics
Testing the Study Drug CB-011 for Treatment of Multiple Myeloma
The purpose of this study is to learn more about the study drug CB-01. We want to see if it is safe and helpful for treating people with a type of blood cancer called multiple myeloma that has come back or did not respond to other treatments. This drug uses special cells from a healthy donor to find and kill cancer cells.
Study Topics
A Study of the Drug Tirabrutinib for Patients with Primary Central Nervous System Lymphoma
Primary Central Nervous System Lymphoma is a rare cancer that occurs within tissues of the brain or the spinal cord. The purpose of this study is to learn more about the study drug Tirabrutinib. We want to see if this study drug is a safe and works well for patients with this type of cancer.
Study Topics
Testing a New Study Device for Tricuspid Regurgitation
The purpose of this study is to test a study device called Edwards EVOQUE system for the treatment of this condition. We want to learn more about the safety and effectiveness of this device.
Study Topics
A Study of the VBX Device for Patients with Peripheral Artery Disease
The purpose of this study is to learn more about the VBX Stent Graft study device. We want to see if the study device is safe and works well for patients with complex iliac occlusive disease, a form of peripheral artery disease. We will compare this study device to another device called Bare Metal Stents and see which one will work better.
Study Topics
Studying the Drug Tulisokibart for Patients with Active Crohn's Disease
The purpose of this study is to test a new drug called Tulisokibart. We want to see if this drug is safe and useful for people with Crohn's disease. We will compare this study drug to a placebo drug to see how well it works.
Study Topics
A Study of the Drug Staccato Alprazolam for Patients with Prolonged Seizures
The purpose of this study is to learn more about the study drug Staccato Alprazolam. We want to see how well the study drug works for treating patients with previous episodes of prolonged seizures. We also want to learn more about the safety and side effects that may be caused by the study drug.
Study Topics
A Study of the Drug ABBV-525 to Treat B-cell NonHodgkin's Lymphoma
The purpose of this study is to learn more about the study drug ABBV-525. We want to see if this study drug is safe and useful for the treatment of B-cell non-Hodgkin's Lymphoma that has returned or is not responding to current treatment. We also want to learn about the side effects that may be caused by taking this drug.
Study Topics
Testing a Study Device for Pulmonary Regurgitation
The purpose of this study is to test a study device called Medtronic Harmony Transcatheter Pulmonary Valve for the treatment of this condition. We want to learn more about the safety and effectiveness of this device.
Study Topics
Increasing Appetite in Cancer Patients
This purpose of this study is to see if the study drug, olanzapine, can help cancer patients feel hungrier and help them gain weight. We want to see if olanzapine is better than the usual treatment.
Study Topics
Studying a New Study Catheter to Treat Rapid Heartbeat
The purpose of this study is to learn more about a new study catheter. We want to see if this catheter can help treat episodes of rapid heartbeat in patients with heart problems not caused by blocked arteries or heart attacks. We want to learn more about the safety and effectiveness of this catheter.
Study Topics
Using Upadacitinib to Treat Arthritis in Children and Young People
The purpose of this study is to learn more about treating arthritis in children and young people with the study drug, upadacitinib. We want to see if this treatment works better than the usual treatment.
Study Topics
Arthritis, Lupus, and Autoimmune Disorders Children, Infants, Teen Health
Testing the Study Drug CIN-103 for Treatment of Irritable Bowel Syndrome with Predominant Diarrhea
The purpose of this study is to learn more about the study drug CIN-103 for the treatment of irritable bowel syndrome with predominant diarrhea. We want to see if the study drug can help people have less stomach pain and more solid stools. We also want to learn more about the side effects that may be caused by the study drug.
Study Topics
Using Mavacamten to Treat Adolescents with Cardiomyopathy
Obstructive Hypertrophic Cardiomyopathy (HCM) is a heart condition that makes it hard for the heart to pump blood and may make a person feel weak and tired. The purpose of this study is to see if the study drug, mavacamten, helps young people with obstructive HCM.
Study Topics
Studying a New Pneumococcal Disease Vaccine Among Healthy Toddlers
Your child is being asked to join this study because they are healthy, between 12 to 15 months old, and have had 3 doses of Prevnar 20®. The study will test a new vaccine to see if it can protect against a germ that causes infections in children. The goal is to check if the vaccine is safe and helps the body make antibodies to fight the germ.
Study Topics
Healthy Volunteers Infectious Diseases Screening and Prevention Children, Infants, Teen Health
Testing a Study Device for Treatment of Sudden Tear in the Aorta
The purpose of this study is to find out if the study device called AMDS is safe and works well for treating this condition. We want to see if this device can help heal the aorta's walls and reduce the need for surgery.
Study Topics
Testing a New Home-Use Device for Detection of Irregular Heartbeats
The purpose of this study is to test a new home-use device called SANSA. We want to see if this device helps detect irregular heartbeats compared to the current tests already used by doctors. If successful, this device could help more people get diagnosed and treated for their irregular heartbeats.
Study Topics
A Study of the Drug AAV2-hAQP1 for Treating Dry Mouth Among Head and Neck Cancer Patients
The purpose of this study is to learn more about the study drug called AAV2-hAQP1. We want to see if this study drug can help people who have dry mouth because of radiation treatment for head and neck cancer. We want to check if this study drug will increase saliva and see if it is safe and easy for people to use.
Study Topics
Testing a Study Device for Chronic Venous Insufficiency
Chronic venous insufficiency happens when blood gets stuck in the veins of the legs because the valves do not work right. This study wants to see if the study device Venclose™ digiRF™ Generator and its catheters are safe and good at treating this problem. We want to know if these devices can help fix the veins in the legs and stop them from leaking. The study will also check if the devices are safe to use.
Study Topics
Finding out if Antiviral Medicine Worked for Babies or Toddlers with Cytomegalovirus Infection
The purpose of this study is to learn more about the treatment with antiviral medicine for babies born with cytomegalovirus. We want to see if antiviral medicine has any impact on hearing, cancer risk, overall growth, or sexual development.
Study Topics
Infectious Diseases Children, Infants, Teen Health Ears, Nose, Throat, Mouth