Search Studies
Studying the Drug CB-011 for Treatment of Multiple Myeloma
The purpose of this study is to learn more about the study drug CB-01. We want to see if it is safe and helpful for treating people with a type of blood cancer called multiple myeloma that has come back or did not respond to other treatments. This drug uses special cells from a healthy donor to find and kill cancer cells.
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Studying the Medicine BLEXIMENIB for Patients with Acute Myeloid Leukemia
The purpose of this study is to learn more about a new medicine called BLEXIMENIB. We want to see if it works better when added to two other medicines for people with a kind of blood cancer called acute myeloid leukemia (AML). This study is for people with changes in the KMT2A or NPM1 gene, who are not able to get stronger chemotherapy.
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Studying Brain Cell Treatment to Help Stop Hard-to-Control Seizures
Drug-resistant bilateral mesial temporal lobe epilepsy means a person has seizures in both sides of the brain's memory area that do not get better with medicine. The purpose of this study is to learn more about a new treatment made from special brain cells to help people with this type of epilepsy. Doctors will place these cells into the brain to see if they can safely reduce seizures. The study also checks how well people feel after getting the treatment.
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Early Detection Matters
The purpose of this study is to test recruitment methods to find and sign up people for a blood screening study. The results will help us decide if we can do a bigger study later. You are invited to join because you are at least 30 years old, self-identify as Black and/or African American or are at higher risk for developing MGUS because of a first-degree relative and, live in Charlotte, NC or nearby. This study will also check how many people have a blood condition that might lead to blood cancer.
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Minority Health Screening and Prevention Cancer Cancer: Blood
Studying a New Cancer Treatment for Patients with Blood Cancer
The purpose of this study is to learn more about a new treatment for patients with blood cancer. We want to see if the treatment called AZD0486 when used alone or with other cancer treatment, is safe and useful. We are looking for volunteers with a one of these types of blood cancers: mantle cell lymphoma, chronic lymphocytic leukemia, or small lymphocytic lymphoma. The study team will provide more information.
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Studying the Drug REGN5678 for Patients with Prostate Cancer
The purpose of this study is to learn more about a treatment for patients with prostate cancer. We want to see if the study drug called REGN4336 is safe and useful for patients with castration-resistant prostate cancer that has spread to other parts of the body. Study team will provide more information.
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Studying Vitamin C Levels and Blood Cancer Treatment Outcomes
The purpose of this study is to see if vitamin C levels affect how well treatments work for people with certain types of blood cancer. We will also look at specific genes that might affect vitamin C in the body. This study will help us understand if vitamin C can improve treatment results for these cancers. We are looking for volunteers with acute myeloid leukemia, myelodysplastic syndromes, or chronic myelomonocytic leukemia.
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Studying Diabetes Medicine for Heart and Kidney Health
The purpose of this study is to learn more about two types of diabetes medicines. We want to see which medicine type helps lower the risk of heart and kidney problems. We are looking for volunteers with type 2 diabetes and a history of heart disease or have high risk for heart disease that are patients of Elizabeth Internal Medicine and Carmel Family Physicians.
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Helping Patients with Cancer Quit Smoking With New Therapy
The purpose of this study is to learn more about a kind of therapy called Dialectical Behavior Therapy Skills Training (DBT-ST). We want to see if this therapy can help people with cancer who smoke to smoke less or quit. We want to find out how it affects their feelings, stress, and how they deal with tough situations. We will also see if people with cancer who smoke would be willing to try this therapy if it were part of their regular care.
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Substance Use (Alcohol, Illegal Drugs, Tobacco) Wellness and Lifestyle Cancer
Treating Neuroendocrine Carcinoma with Atezolizumab
The purpose of this study is to see if adding the study drug, atezolizumab, to the usual cancer treatment helps people with a type of cancer that starts outside the lungs called neuroendocrine carcinoma.
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Testing the Study Drug KTX-1001 for The Treatment of Multiple Myeloma
The goal of this study is to learn more about the study drug KTX-1001. We want to find out if this drug is safe for patients with multiple myeloma that has returned or didn't respond to treatment. We also want to see if patients can handle the taking the drug.
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Testing the Study Drug INX-315 for Patients with Advanced Cancer
The purpose of this study is to learn more about the study drug INX-315. We want to see if this study drug is a safe treatment for patients with certain types of advanced cancer or cancer that has spread to other parts of the body. Study team will provide more information on eligibility criteria.
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Testing the Study Drug PRO1160 for Advanced Kidney, Throat, and Blood Cancers
The purpose of this study is to learn more about the new drug PRO1160. We want to see if it is safe and helpful for treating patients with cancer that didn't fully respond to treatment or has come back. Volunteers must have kidney cancer, throat cancer, or a type of blood cancer called non-Hodgkin lymphoma.
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Cancer Cancer: Ear, Nose, Mouth, Throat Cancer: Kidney, Liver, Pancreas Cancer: Lymphoma
A Study of the Drug Efruxifermin for Treating Liver Diseases and Scarring of the Liver
Non-alcoholic steatohepatitis and metabolic dysfunction-associated steatohepatitis are types of fatty liver disease that cause scarring of the liver. We want to learn more about the safety and effects when using the study drug Efruxifermin to treat these diseases.
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Using Technology to Improve Care for Teens with Inflammatory Bowel Disease
Inflammatory bowel disease (IBD) affects the digestive system. Types of IBD include Ulcerative Colitis and Crohn's disease. The purpose of this study is to find out if text messaging can be used to help care for people with IBD. Volunteers must have a smartphone with text messaging.
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Electromagnetic Treatment for Stroke Recovery
The purpose of this study is to see if a wearable device helps stroke recovery. The device uses low-frequency electromagnetic fields to activate the brain. Volunteers must have had stroke onset 4 to 21 days ago.
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A Study of the Drug Efruxifermin for Patients with Liver Disease
The goal of this study is to find out if a drug called efruxifermin can help people with liver scarring caused by liver disease. We also want to know if the drug is safe and helpful for patients. Volunteers must have a liver disease where too much fat builds up, causing inflammation and scarring. Study team will provide more information.
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Learning More About the Long-Term Use of the Study Drug Staccato Alprazolam for Prolonged Seizures
The purpose of this study is to learn more about the long-term use of the study drug Staccato Alprazolam. We want to see how well the study drug works when used long-term for patients with a history of prolonged seizures. We also want to learn more about the safety and side effects that may be caused by the study drug.
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Comparing Ways to Improve Blood Flow in Newborns' Lungs
The purpose of this study is to looks at two different methods to help increase blood flow in the lungs of newborn babies. One method uses a shunt, which is a small tube, and the other uses a stent, which is a tiny mesh-like device. We want to learn if one of the two options is better than the other.
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Testing a New Study Device for Mitral Valve Dysfunction
The purpose of this study is to test a new study device called the Cephea Mitral Valve System for the treatment of this condition. We want to learn more about the safety and effectiveness of this device.
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