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Studying a New CAR T Treatment for Multiple Myeloma
The purpose of this study is to learn more about a new treatment called arlo‑cel for people with multiple myeloma. The study will compare this new treatment to standard cancer medicines to see which works better and is safer. This study is for volunteers with multiple myeloma whose cancer came back or did not improve after other treatments.
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Understanding Needs of Young People With Cancer
This study aims to learn what young people with cancer need most while getting care and after treatment. We want to understand what topics they want more education and support about, such as health, emotions, and daily life. What we learn will help improve programs and services for young people with cancer. We are looking for volunteers who were between 15 and 39 years old when they were diagnosed with cancer and are currently getting cancer treatment or have had cancer treatment in the past.
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Studying a New Implant for Stress Urinary Incontinence
Stress Urinary Incontinence (SUI) is a common type of urine leakage among men. The purpose of this study is to test how safe and how well a new implanted device works for this condition. The device is designed to help men who leak urine during activities like coughing or exercising. Our researchers want to see if it can reduce urine leaks and improve daily life. We are looking for male volunteers who have been diagnosed with SUI for at least 6 months.
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Communities Against Cancer: A Survey for Change
The purpose of this study is to learn about how people in our area take care of their health and what challenges they face with cancer. We hope to understand what people need and how we can help them better. The answers from this survey will help us make plans to support our community.
Study Topics
Men's Health Opinions, Social Issues Screening and Prevention Wellness and Lifestyle Women's Health Cancer Other
Studying a New Medicine to Help People With ATTR Heart Disease
ATTR amyloidosis is a disease where a protein called transthyretin builds up in the body and causes problems, especially in the heart and nerves. The purpose of this study is to learn more about a new medicine called nucresiran to help people with this disease.
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Studying the Medicine Migalastat for Children with Fabry Disease
Fabry disease is a rare genetic condition where the body cannot break down certain fats, causing them to build up and damage organs like the heart, kidneys, and nerves. The purpose of this study is to learn more about the medicine migalastat for this condition. Our researchers want to see if it is safe and helpful for children.
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Genetic Disorders Rare Disease Children, Infants, Teen Health
Comparing Two Medicines for ALK‑Positive Lung Cancer
The purpose of this study is to learn more about a new medicine called NVL‑655 for non‑small cell lung cancer that is ALK‑positive. Our researchers want to see if NVL‑655 works better and is safer than a commonly used medicine called alectinib. The goal is to learn which treatment helps stop the cancer from getting worse for a longer time.
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Studying the Drug Tulisokibart for Patients with Active Crohn's Disease
The purpose of this study is to test a new drug called Tulisokibart. We want to see if this drug is safe and useful for people with Crohn's disease. We will compare this study drug to a placebo drug to see how well it works.
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Mobile App Support for Young Women with Breast Cancer
The purpose of this study is to look at a new way to better support young women with breast cancer. Our researchers will look at whether a mobile app can provide support and help lower stress. The app lets women connect with others and learn helpful information. This study is for volunteers who have been diagnosed with breast cancer at any stage.
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Studying the Oral Medicine Icotrokinra for Ulcerative Colitis
The purpose of this study is to learn more about the medicine Icotrokinra. Our researchers want to see if this medicine can safely control symptoms of ulcerative colitis. We also want to learn if this medicine can help people feel better and keep their disease under control over time.
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Studying the Drug Linvoseltamab for Untreated Multiple Myeloma
The purpose of this study is to learn more about the study drug Linvoseltamab. We want to find out if this study drug is safe and helpful for treating patients with newly diagnosed multiple myeloma who have not had any treatment before. We also want to see how well patients can handle this drug.
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Looking at Arm Size Differences in Kids with a Certain Type of Elbow Fracture
The purpose of this study is to gather information that might help us create a more accurate way to measure arm swelling when a child fractures their elbow. Using the same way to measure swelling might help doctors make decisions on treatment that can impact how kids heal from these types of injuries.
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Studying How Genes Affect the Way Medicine Works for People
The purpose of this study is to learn more about how people's genes affect how they respond to medicine. We will collect cheek swabs or blood samples to be stored and used in future research. Information from this study may help doctors give better treatments to people in the future.
Study Topics
Healthy Volunteers Screening and Prevention Wellness and Lifestyle Other
Studying a Type of Blood Test Used to Find Cancer in People With Sarcoma
The purpose of this study is to look at how well a special blood test called LP-WGS can find cancer in people with bone or soft tissue sarcoma (a type of cancer).
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Studying Two Medicines for Non-Small Cell Lung Cancer
The goal of this study is to learn how two medicines work together to treat non-small cell lung cancer. We want to find out if the medicines called amivantamab and Lazertinib are safe and helpful for people who have a certain change in a gene called EGFR.
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Helping Young Cancer Survivors Feel Better Using a Digital Tool
The purpose of this study is to learn more about a new digital tool to help adolescents and young adult cancer survivors manage their symptoms of depression. People in the study will use the tool, answer questions, and join a video call. The goal is to find out if the tool helps them manage their feelings better. All study visits and consultations will be done virtually.
Study Topics
Mental Health Cancer Cancer: Children, Teens Children, Infants, Teen Health
Studying the Medicine Sonrotoclax for Patients with Blood Cancer
The purpose of this study is to learn more about a new medicine called sonrotoclax. We want to see if this medicine works better and is safe for people with a type of blood cancer called chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). We will compare the medicine to other approved treatments to see which one helps more. The goal is to help people feel better and live longer.
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Studying New Medicine and Chemo for Rare Throat Cancer
The purpose of this study is to see if adding a new medicine called nivolumab to regular chemotherapy helps treat a rare throat cancer called nasopharyngeal carcinoma. We will also look at whether children can get less radiation and have fewer side effects. The goal is to find safer and better ways to treat this cancer.
Study Topics
Cancer Cancer: Children, Teens Cancer: Ear, Nose, Mouth, Throat
Studying a New mRNA Medicine for Blood Cancer
The purpose of this study is to learn more about a new medicine called mRNA-2808 for people with multiple myeloma, a type of blood cancer. This medicine helps teach your immune system how to find and kill cancer cells. The goal is to see if the medicine is safe and to find the best dose. Researchers will also study how it affects the cancer and the body.
Study Topics