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Comparing Hearing Loss in Cancer Patients
The purpose of this study is to find out if giving chemotherapy drugs on a faster schedule helps patients with advanced germ cell tumors. We will compare the regular 3-week cycle with a faster paced 2-week cycle. We want to see if the faster schedule is useful and safe for the patients.
Study Topics
Cancer Cancer: Children, Teens Cancer: Rare Cancers Cancer: Solid Tumor
Improving Cancer Care for Young Patients
The purpose of this study to find better ways to diagnose, treat, and prevent cancers in children, teenagers, and young adults. Our goal is to gather information about cancer treatments and their results to improve future care. We are looking for volunteers who have cancer or other conditions where cells grow abnormally. The study team will provide more details.
Study Topics
Comparing Chemotherapy Schedules for Germ Cell Tumors
The purpose of this study is to find out if giving chemotherapy drugs on a faster schedule helps patients with advanced germ cell tumors. We will compare the regular 3-week cycle with a faster paced 2-week cycle. We want to see if the faster schedule is useful and safe for the patients.
Study Topics
Comparing a New Treatment For Blood Cancer Patients
The purpose of this study is to learn about a new treatment called Inotuzumab Ozogamicin. We want to see if it helps people with blood cancer. We will compare the results of patients who get this new treatment with those who get the usual treatment. We are looking for volunteers who are newly diagnosed with one of these blood cancers: high-risk B-cell acute lymphoblastic leukemia (B-ALL), mixed-phenotype acute leukemia (MPAL), or disseminated B lymphoblastic lymphoma (B-LLy).
Study Topics
Cancer Cancer: Blood Cancer: Children, Teens Cancer: Leukemia
Comparing Medicines for Newly Diagnosed Multiple Myeloma
The purpose of this study is to learn which of two medicines works better for people with a newly diagnosed blood cancer called multiple myeloma. We will see how iberdomide and lenalidomide help after a stem cell transplant and how they affect health and daily life.
Study Topics
Studying a New Cell Therapy for People With Multiple Myeloma
The purpose of this study is to learn more about a new treatment made from a person's own immune cells. Our researchers want to see if this treatment can be used to treat multiple myeloma that has come back or stopped responding to treatment. The study compares this new treatment to standard treatments doctors already use. Researchers want to see which treatment works better and is safer for patients.
Study Topics
Studying a New CAR T Treatment for Multiple Myeloma
The purpose of this study is to learn more about a new treatment called arlo‑cel for people with multiple myeloma. The study will compare this new treatment to standard cancer medicines to see which works better and is safer. This study is for volunteers with multiple myeloma whose cancer came back or did not improve after other treatments.
Study Topics
Understanding Needs of Young People With Cancer
This study aims to learn what young people with cancer need most while getting care and after treatment. We want to understand what topics they want more education and support about, such as health, emotions, and daily life. What we learn will help improve programs and services for young people with cancer. We are looking for volunteers who were between 15 and 39 years old when they were diagnosed with cancer and are currently getting cancer treatment or have had cancer treatment in the past.
Study Topics
Studying a New Implant for Stress Urinary Incontinence
Stress Urinary Incontinence (SUI) is a common type of urine leakage among men. The purpose of this study is to test how safe and how well a new implanted device works for this condition. The device is designed to help men who leak urine during activities like coughing or exercising. Our researchers want to see if it can reduce urine leaks and improve daily life. We are looking for male volunteers who have been diagnosed with SUI for at least 6 months.
Study Topics
Communities Against Cancer: A Survey for Change
The purpose of this study is to learn about how people in our area take care of their health and what challenges they face with cancer. We hope to understand what people need and how we can help them better. The answers from this survey will help us make plans to support our community.
Study Topics
Men's Health Opinions, Social Issues Screening and Prevention Wellness and Lifestyle Women's Health Cancer
Studying a New Medicine to Help People With ATTR Heart Disease
ATTR amyloidosis is a disease where a protein called transthyretin builds up in the body and causes problems, especially in the heart and nerves. The purpose of this study is to learn more about a new medicine called nucresiran to help people with this disease.
Study Topics
Comparing Two Medicines for ALK‑Positive Lung Cancer
The purpose of this study is to learn more about a new medicine called NVL‑655 for non‑small cell lung cancer that is ALK‑positive. Our researchers want to see if NVL‑655 works better and is safer than a commonly used medicine called alectinib. The goal is to learn which treatment helps stop the cancer from getting worse for a longer time.
Study Topics
Studying the Medicine Migalastat for Children with Fabry Disease
Fabry disease is a rare genetic condition where the body cannot break down certain fats, causing them to build up and damage organs like the heart, kidneys, and nerves. The purpose of this study is to learn more about the medicine migalastat for this condition. Our researchers want to see if it is safe and helpful for children.
Study Topics
Genetic Disorders Rare Disease Children, Infants, Teen Health
Studying the Drug Tulisokibart for Patients with Active Crohn's Disease
The purpose of this study is to test a new drug called Tulisokibart. We want to see if this drug is safe and useful for people with Crohn's disease. We will compare this study drug to a placebo drug to see how well it works.
Study Topics
Studying the Oral Medicine Icotrokinra for Ulcerative Colitis
The purpose of this study is to learn more about the medicine Icotrokinra. Our researchers want to see if this medicine can safely control symptoms of ulcerative colitis. We also want to learn if this medicine can help people feel better and keep their disease under control over time.
Study Topics
Looking at Arm Size Differences in Kids with a Certain Type of Elbow Fracture
The purpose of this study is to gather information that might help us create a more accurate way to measure arm swelling when a child fractures their elbow. Using the same way to measure swelling might help doctors make decisions on treatment that can impact how kids heal from these types of injuries.
Study Topics
Comparing Two Medicines for Essential Thrombocythemia
The purpose of this study is to see if a new medicine called bomedemstat is safe and works well for people with a blood disease called essential thrombocythemia. We will compare bomedemstat to another medicine called hydroxyurea. The goal is to find out which medicine helps more with symptoms like tiredness and high platelet counts.
Study Topics
Studying How Genes Affect the Way Medicine Works for People
The purpose of this study is to learn more about how people's genes affect how they respond to medicine. We will collect cheek swabs or blood samples to be stored and used in future research. Information from this study may help doctors give better treatments to people in the future.
Study Topics
Healthy Volunteers Screening and Prevention Wellness and Lifestyle
Studying a Type of Blood Test Used to Find Cancer in People With Sarcoma
The purpose of this study is to look at how well a special blood test called LP-WGS can find cancer in people with bone or soft tissue sarcoma (a type of cancer).
Study Topics
Studying Two Medicines for Non-Small Cell Lung Cancer
The goal of this study is to learn how two medicines work together to treat non-small cell lung cancer. We want to find out if the medicines called amivantamab and Lazertinib are safe and helpful for people who have a certain change in a gene called EGFR.
Study Topics