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Studying Durvalumab for Patients with High-Risk Liver Cancer
The purpose of this study is to learn more about the study drug Durvalumab when combined with classic chemotherapy. We want to find out if this approach is better or worse than the usual approach for your liver cancer.
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Finding Out How Well Selinexor Works for Treating Brain Cancer
The purpose of this study is to find the safest dose of the study drug, Selinexor. We also want to find out if adding the study drug is better than the usual treatment for brain cancer.
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Studying Two Ways to Treat Stomach Cancer
The purpose of this study is to learn more about different ways to treat stomach cancer. Our researchers want to see if giving a cancer medicine called paclitaxel directly into the belly, along with regular chemotherapy, can help lower the chance of stomach cancer growing or spreading. We will compare this new treatment to the usual care most people get for stomach cancer.
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Studying CAR T-Cell Therapy for Aggressive B-Cell Lymphoma
The purpose of this research is to find new ways to treat lymphomas that have come back or stopped responding to treatment. Researchers will study a new cell therapy made from a person's own immune cells for aggressive B‑cell lymphoma. The study looks at how safe this treatment is and how well it helps shrink or control the cancer.
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Studying a New Medicine for Severe Heart Failure
The purpose of this study is to learn more about a cancer medicine called venetoclax. We want to see if adding this medicine to the usual chemotherapy can help treat patients with newly diagnosed myeloid leukemia (AML). We will compare this new treatment to the usual treatment for this type of cancer.
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Testing the Study Drug SNDX-5613 for Patients with Newly Diagnosed Acute Myeloid Leukemia
The purpose of this study is to learn more about the study drug SNDX-5613. We want to see if adding this study drug to the usual treatment can help patients who have just been diagnosed with a type of blood cancer called acute myeloid leukemia. We want to find out how much of the drug will cause serious side effects in patients. This will help doctors find out the best amount of the drug to use in future treatments for this cancer.
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Studying Care Choices After Breast Cancer Surgery
The purpose of this study is to compare two different approaches to care for breast cancer after surgery. Our researchers want to find out whether closely monitoring patients after surgery works just as well as giving additional medication to prevent the cancer from returning. This study is for volunteers who had triple-negative breast cancer and showed no signs of cancer after completing chemotherapy and surgery. The results will help doctors determine the best way to care for patients in this situation.
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Studying the Supplement Fisetin to Help Cancer Survivors with Tiredness
The purpose of this study is to learn more about fisetin, a dietary supplement. We want to find out if this supplement can help reduce tiredness in people who have had cancer treatments. We will compare this supplement to a placebo. We are looking for volunteers who previously had cancer treatments that often cause tiredness. The study team will provide more information.
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Studying New Drug Combinations for Advanced Small Cell Lung Cancer
The purpose of this study is to find the highest safe dose of a new drug, iadademstat, when used with other cancer drugs (atezolizumab or durvalumab) in people with advanced small cell lung cancer. The study will check for side effects and see how well the drug combination works. This may help doctors learn if this new treatment is better or worse than the usual care for this cancer.
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Finding the Best Blood Cancer Treatment Using Blood Tests
The purpose of this study is to find out if doctors can quickly test blood and bone marrow to look for signs that help choose the best cancer treatment. These signs, called markers, can show which treatments might work best. If your test shows certain markers, you might be able to join a special treatment group. If not, your doctor will give you the usual care. We are looking for volunteers who have previously untreated acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS).
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Adding Chemotherapy to Hormone Treatment for Advanced Prostate Cancer
The purpose of this study is to see if adding a chemotherapy drug called docetaxel to standard hormone treatment can slow down advanced prostate cancer. Researchers want to learn if this combination works better than hormone treatment alone. The results may help improve care for people with prostate cancer in the future.
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Studying a New Treatment Combination for Nasopharyngeal Cancer
The purpose of this study is to learn more about combining a medicine called nivolumab to chemotherapy for people with newly diagnosed nasopharyngeal cancer. Our researchers also want to see if some children can safely receive less radiation based on how well the cancer responds. The goal is to treat the cancer while lowering side effects.
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Studying the Medicine Triptorelin to Protect Ovaries During Chemotherapy
The purpose of this study is to learn more about a medicine called triptorelin. We want to find out if it can help protect the ovaries of teens and young adults during cancer treatment. Some cancer drugs can damage the ovaries and make it harder to have children later in life. Our researchers are studying this medicine to see if it works better than the usual methods used to protect the ovaries. We are looking for women volunteers with cancer who are receiving a specific type of chemotherapy called an alkylating agent.
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Stem Cell Transplant After Chemotherapy for Lymphoma Patients
The purpose of this study is to find out if giving a stem cell transplant after chemotherapy helps people with Peripheral T-cell Lymphoma stay healthy longer. Doctors will compare people who get the transplant to people who do not. The goal is to see which way works better to keep the cancer from coming back.
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Studying Cirtuvivint for Blood Cancer
The purpose of this study is to learn more about a medicine called cirtuvivint for certain blood cancers. Our researchers will study this medicine by itself or together with another pill called ASTX727. We want to learn how safe these medicines are, find the best dose, and see how they affect the cancer. This study is for volunteers with myelodysplastic syndromes (MDS) or acute myeloid leukemia (AML).
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Study of the Drug Inotuzumab Ozogamicin in Patients with Disseminated B-cell Lymphoblastic Lymphoma
The purpose of this study is to find out if the study drug, Inotuzumab Ozogamicin, can help treat certain types of leukemia. The study drug will be given along with the usual chemotherapy.
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Learning More About The Medicine Duvelisib T-cell Lymphoma
The purpose of this study is to learn more about treating peripheral T-cell lymphoma with the study drug Duvelisib or Azacitidine. One of the study drugs will be given along with the usual treatment. We want to see how well the combination treatment works. We also want to learn more about possible side effects.
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Studying Plixorafenib for Cancers with BRAF Gene Changes
The purpose of this study is to learn more about the medicine plixorafenib. We want to see if this medicine can help people whose cancer has a change in the BRAF gene. The medicine is being studied to see if it works and if it is safe. People in the study will take the medicine and be watched closely for any changes or side effects.
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A Study of the Drug Reparixin for Patients with Myelofibrosis
The purpose of this study is to learn more about the study drug Reparixin. This study drug is for people with a type of blood cancer called myelofibrosis. We want to find out if Reparixin is safe and if it helps treat this cancer.
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Using the TheraBionic Device to Treat Advanced Pancreatic Cancer
The purpose of this study is to find out how the TheraBionic device will affect pancreatic cancer. The TheraBionic device is a small portable device. We want to see if the device will prevent cancer growth.
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