Search Studies
Testing the Study Drug XmAb819 for Patients with Kidney Cancer
The purpose of this study is to test a new drug called XmAb819. We want to see if this study drug is safe and works well for volunteers with clear cell renal cell carcinoma that has come back or not responded to other treatments.
Study Topics
Studying the Drug SGR3515 for Patients with Advanced Solid Tumors
The study aims to learn about the drug SGR-3515. We want to see if it is safe and works well for treating advanced solid tumors. We also want to find the best dose and schedule for treating your cancer. We are looking for volunteers with advanced solid tumors who have either stopped benefiting from or cannot tolerate previous treatments, or whose cancer has returned.
Study Topics
Learning About Tiredness in Lung Cancer Patients
We want to understand why people with a type of lung cancer feel tired. We also want to know if exercise can help and how caregivers can support patients in staying active. We are looking for volunteers who have a type of lung cancer called non-small cell lung cancer or are caregivers for someone with it. This study will last around 3 months.
Study Topics
Studying Opioid Use After Cancer Surgery
The purpose of this study is to see how many pain pills are taken by cancer patients after surgery. We also want to see how patients get rid of leftover pills and how happy they are with their care. We are looking for volunteers who are already scheduled to have surgery to remove their bladder, kidney, or prostate because of cancer at Atrium Health Wake Forest Baptist Comprehensive Cancer Center.
Study Topics
Cancer Cancer: Kidney, Liver, Pancreas Cancer: Prostate Cancer: Urinary and Bladder
Studying a New Biomarker to Predict Breast Cancer Return
The goal of this study is to learn more about a new test called Oncodetect™. This test looks for signs of breast cancer in the blood. We want to see how well this test can find cancer coming back during and after treatments like surgery or radiation.
Study Topics
Studying a New Medicine for Multiple Myeloma
The purpose of this study is to learn more about a new medicine called JNJ-79635322. Researchers want to see if this medicine can safely help people with multiple myeloma that has come back or did not respond to past treatments.
Study Topics
Studying New Treatment Timing for Advanced Cervical Cancer
The purpose of this study is to see if starting treatment with chemotherapy and immunotherapy before standard radiation treatment works better for advanced cervical cancer. Our researchers will compare two treatment plans to learn which one helps people live longer and keeps the cancer from getting worse. The study will also look at side effects and how safe the treatments are. This study is for volunteers with newly diagnosed advanced cervical cancer.
Study Topics
Using a Blood Test to Guide Colon Cancer Treatment
The purpose of this study is to find out if a blood test can help doctors choose the best kind of chemotherapy for people who had surgery for colon cancer. This blood test looks for something called ctDNA. ctDNA is tiny pieces of DNA from cancer cells that can be found in your blood. We want to see if using this blood test is better or worse than the usual way of deciding on treatment. We are looking for volunteers who have colon cancer and have been treated with surgery.
Study Topics
Using Stereotactic Body Radiation Therapy to Treat Lung Cancer
The purpose of this study is to compare the usual treatment alone to using an additional treatment called Stereotactic Body Radiation Therapy plus the usual treatment.
Study Topics
Using a Tracker to Learn More about Heart Rate Variability Changes and Cancer-Related Tiredness
This study aims to help people with pancreatic and breast cancer who feel very tired because of their illness. We will use an activity tracker to check changes in your heart rate variability and how well you sleep. We will also ask you to fill out surveys and keep a diary about your tiredness. The information we collect may help us understand how heart rate variability changes are related to cancer-related tiredness. This study will last around 1 month.
Study Topics
Studying Extra Therapies People Use During Cancer Treatment
The purpose of this study to learn more about other ways people manage their cancer symptoms while they are getting treatment. These other ways include using things like cannabis (also called marijuana), vitamins or supplements, and doing activities like acupuncture or meditation. We want to find out if these methods help or hurt people compared to the usual care they get from their doctor.
Study Topics
Cancer Cancer: Breast Cancer: Colon, Rectum, Anus Cancer: Lung Cancer: Lymphoma Cancer: Skin
Studying a New Treatment to Help Stop High‑Risk Bladder Tumors
The purpose of this study is to learn more about a new treatment for people with bladder cancer that has not spread into the muscle but could become more serious over time. This is called high-risk, non-muscle invasive bladder cancer (NMIBC). Our researchers want to see if a treatment called cretostimogene grenadenorepvec can safely kill cancer cells, stop the tumor from coming back, and for how long it can help.
Study Topics
Studying Digoxin to Help Treat Brain Cancer
The purpose of this study is to learn more about a medicine called digoxin. We want to see if this medicine can help stop a type of brain cancer called medulloblastoma from getting worse. The goal is to learn if this treatment can help and to understand any side effects it may cause. We are looking for volunteers who have been diagnosed with medulloblastoma.
Study Topics
Cancer Cancer: Brain, Nervous System, Spinal Cord Cancer: Rare Cancers Children, Infants, Teen Health
Testing the Study Drug Olvi-Vec for Ovarian Cancer that Resists Treatment
The purpose of this study is to learn about the drug Olvi-Vec. We want to see if it is safe and helpful for treating ovarian, fallopian tube, or peritoneal cancer that did not get better with a type of treatment called platinum-based chemotherapy.
Study Topics
Studying Treatment Options for Multiple Myeloma After a Stem Cell Transplant
The purpose of this study is to find out which treatment works best to keep multiple myeloma from coming back after a stem cell transplant. Our researchers will compare three options: a new medicine called teclistamab with standard treatment called lenalidomide, lenalidomide alone, or teclistamab alone. The goal is to see which treatment helps people stay healthy longer.
Study Topics
Helping Improve Breast Cancer Care for Young Women
The purpose of this study is to learn more about breast cancer in younger women and help improve care in the future. Researchers will collect blood, tissue, and stool samples from women who were diagnosed with breast cancer between the ages of 18 and 45. They will look for patterns and differences to help guide future research and treatment.
Study Topics
Using NK Cells to Treat Sarcoma
The purpose of this study is to see if adding a special type of immune cell called "natural killer" (NK) cells to chemotherapy can help treat cancer better. NK cells are good at finding and killing cancer cells.
Study Topics
Cancer Cancer: Children, Teens Cancer: Sarcoma (Bone, Muscle, Soft Tissue)
Collecting Samples to Learn About Childhood Cancer
The purpose of this study is to find better treatments in the future for children with cancer. We want to create a large collection of blood and tissue samples from children cancer to help doctors learn more about how cancer and the immune system work together. Information from this study may help us find better ways to treat cancer in the future. We are looking for volunteers who have been diagnosed with any type of pediatric cancer and are under the care of a doctor at Atrium Health.
Study Topics
Studying the Drug SNDX-5613 for Patients with Acute Myeloid Leukemia
The study aims to learn more about the drug SNDX-5613. We want to find the best dose for patients with a blood cancer called acute myeloid leukemia. We also want to see how this drug works when used with two other drugs, daunorubicin and cytarabine.
Study Topics
Studying Blood Particles to Help Treat Cancer
The purpose of this study is to learn more about tiny particles in the blood called extracellular vesicles. By studying this, we hope to find out more about different types of cancer and how to treat them better. We will look at the blood samples from patients with similar cancers to see if we can discover new information. This could help doctors choose the best treatments for cancer patients in the future. We are looking for volunteers with urothelial, prostate, or kidney cancer. The study team will provide more information.
Study Topics