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Comparing a New Treatment For Blood Cancer Patients
The purpose of this study is to learn about a new treatment called Inotuzumab Ozogamicin. We want to see if it helps people with blood cancer. We will compare the results of patients who get this new treatment with those who get the usual treatment. We are looking for volunteers who are newly diagnosed with one of these blood cancers: high-risk B-cell acute lymphoblastic leukemia (B-ALL), mixed-phenotype acute leukemia (MPAL), or disseminated B lymphoblastic lymphoma (B-LLy).
Study Topics
Cancer Cancer: Blood Cancer: Children, Teens Cancer: Leukemia
Improving Cancer Care for Young Patients
The purpose of this study to find better ways to diagnose, treat, and prevent cancers in children, teenagers, and young adults. Our goal is to gather information about cancer treatments and their results to improve future care. We are looking for volunteers who have cancer or other conditions where cells grow abnormally. The study team will provide more details.
Study Topics
Comparing Chemotherapy Schedules for Germ Cell Tumors
The purpose of this study is to find out if giving chemotherapy drugs on a faster schedule helps patients with advanced germ cell tumors. We will compare the regular 3-week cycle with a faster paced 2-week cycle. We want to see if the faster schedule is useful and safe for the patients.
Study Topics
Learning More about a New AML Cancer Treatment
The purpose of this study is to learn more about a cancer medicine called venetoclax. We want to see if adding this medicine to the usual chemotherapy can help treat patients with newly diagnosed myeloid leukemia (AML). We will compare this new treatment to the usual treatment for this type of cancer.
Study Topics
Studying the Drug VX-670 for Adults with Myotonic Dystrophy Type 1
The purpose of this study is to learn more about the study drug VX-670. We want to find out if it is safe and if adults with myotonic dystrophy type 1 can handle it well.
Study Topics
Testing if Oxytocin Helps You Feel Less Heat Pain After a Mild Sunburn
The purpose of this study is to see how oxytocin affects your ability to feel touch and heat. They will give you oxytocin through an IV (a tube in your vein). They will test this on normal skin and on skin that has a mild sunburn from UV-B light. In this study, you will either get oxytocin or a placebo (a fake solution that doesn't do anything).
Study Topics
Testing a New Formula of Cladribine for Patients with Generalized Myasthenia Gravis
Generalized myasthenia gravis is a condition where the body's defense system attacks the muscles, making them weak and tired. The purpose of this study is to find out how well a new medicine called Cladribine works compared to a fake medicine. We also want to see how well patients can handle the new medicine.
Study Topics
Things that May Predict Memory Decline or Dementia in Adults (Healthy Brain Study)
This study is being done to look at changes in memory, thinking and brain structure in older adults. We will also study how the body processes sugar and how that may relate to change in brain function over time.
Study Topics
Testing Spinal Cord Stimulation for Stiffness and Pain in Stiff Person Syndrome
Stiff person syndrome is a rare disease that makes your muscles very stiff and can cause painful muscle spasms. This study wants to find out if using spinal cord stimulation can help make these symptoms better.
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A Study of the Drug Reparixin for Patients with Myelofibrosis
The purpose of this study is to learn more about the study drug Reparixin. This study drug is for people with a type of blood cancer called myelofibrosis. We want to find out if Reparixin is safe and if it helps treat this cancer.
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Studying the Safety of the Flu Vaccine and COVID-19 Vaccine Among Pregnant People
The purpose of this study is to find out if it is safe for pregnant people to get the flu and COVID-19 vaccines together. We will compare getting both shots on the same day or 7-14 days apart.
Study Topics
Treating Low-Risk, Early Stage Breast Cancer with Hormonal Therapy
The usual treatment for low-risk breast cancer is radiation and hormonal therapy. The purpose of this study is to find out how well hormonal therapy alone will work. We want to find out if this approach is better or worse than the usual approach.
Study Topics
Finding the Best Blood Cancer Treatment Using Blood Tests
The purpose of this study is to find out if doctors can quickly test blood and bone marrow to look for signs that help choose the best cancer treatment. These signs, called markers, can show which treatments might work best. If your test shows certain markers, you might be able to join a special treatment group. If not, your doctor will give you the usual care. We are looking for volunteers who have previously untreated acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS).
Study Topics
Collecting Samples to Learn About Childhood Cancer
The purpose of this study is to find better treatments in the future for children with cancer. We want to create a large collection of blood and tissue samples from children cancer to help doctors learn more about how cancer and the immune system work together. Information from this study may help us find better ways to treat cancer in the future. We are looking for volunteers who have been diagnosed with any type of pediatric cancer and are under the care of a doctor at Atrium Health.
Study Topics