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Can Immunotherapy Help Non-Small Cell Lung Cancer Patients Improve Physical Function
The purpose of this study is to see if treatment with immunotherapy can help lung cancer patients who get tired easily and struggle with some daily tasks.
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Is it More Helpful to Give Children with Germ Cell Tumors Chemotherapy on a Faster Schedule
A germ cell tumor is a type of cancer found in the ovaries for females or the testes for males. This tumor may also be found in the pelvis along the tailbone, chest, abdomen, and other structures of the body. Chemotherapy is the medicine used to fight cancer. We want to find out if giving children with germ cell tumors chemotherapy on a faster schedule is effective.
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Targeted Drug Treatment for Patients with Growing Brain Tumors
The purpose of this study is to see if certain drugs work better for people with meningiomas (a type of brain tumor) that have specific gene changes. The goal is to see if using genetic testing can help pick the best treatment. Researchers hope this will help shrink tumors and improve care for future patients.
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Combination Chemotherapy for Newly Diagnosed and Relapsed Wilms Tumor
The purpose of this study is to find out if we can improve treatment for those with Wilms tumors. We will be testing three different combinations of radiation and chemotherapy. The combination you receive will depend on your type of Wilms tumor.
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Cancer Cancer: Kidney, Liver, Pancreas Children, Infants, Teen Health
I-SPY 2 TRIAL: Study of New Drugs to Treat Breast Cancer Before Surgery
The purpose of this study is to learn more about giving the best treatment at the right time. Treatment on this study will be given before surgery. This allows us to better understand how different people's breast cancers respond to commonly used chemotherapy with or without new drugs.
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Learning More About Treating Gastric, Gastroesophageal Junction and Pancreatic Tumors with ASP2138
The purpose of this study is to find out how well the study drug, ASP2138, works for treating gastric, gastroesophageal junction or pancreatic tumors. We also want to learn more about the side effects that may be caused by the study drug.
Study Topics
Cancer Cancer: Kidney, Liver, Pancreas Cancer: Stomach and Intestines
A Study of the Drug ABBV-383 for Patients with Multiple Myeloma
The purpose of this study is to learn more about the study drug ABBV-383 for patients with multiple myeloma that has returned or has not responded to treatment. We want to find the best dose and learn about the safety and effects of the study drug.
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Internet-Based Program to Help Cancer Survivors Manage Pain
The purpose of this study is to learn more about an internet-based pain program combined with pain education. We want to see if the pain program and education can help reduce pain and improve impact on daily activities. We also want to see if this approach is better or worse than the usual approach.
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Low Muscle Mass and its Role in Side Effects from Colorectal Cancer Treatment in Older Adults
The purpose of this study is to find out if low muscle mass plays a role in side effects from colorectal cancer treatment.
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Treating Head and Neck Cancer with Cetuximab
The purpose of this study is to see how well the drug Cetuximab works for treating head/neck cancer that stopped responding to treatment. It is possible that Cetuximab may work better when given in patients who have already had immunotherapy.
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Collecting Blood and Tissue Samples from Patients with Blood Cancer (myeloproliferative neoplasms)
The goal of this study is to gather blood and tissue samples from patients with a type of blood cancer (myeloproliferative neoplasms). The samples will be used to help find new approaches to treatment.
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Comparing Two Different Methods of Surgery to Treat Osteosarcoma that Has Spread to the Lungs
The purpose of this study is to compare two different surgery methods for people with osteosarcoma that has spread to the lung. We want to find out which surgery method is better. One method is called open thoracic surgery. It is done through a single large cut between the ribs, opens the chest, and removes the cancer. The other method is called thoracoscopy. It is done through several small incisions and uses a small camera to help with removing the cancer. Both methods are considered standard treatment.
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Study of Quick Start Durvalumab for Treating Stage III Non-Small Cell Lung Cancer
Durvalumab is usually started 30 days or more after radiation treatment. The purpose of this study is to find out if it is possible to start Durvalumab within 14 days after radiation treatment. We want to see how the quick start affects you and your cancer.
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Learning More About Adding TRC102 to the Usual Non-Small Cell Lung Cancer Treatment
The purpose of this study is to learn more about the study drug, TRC102. We want to see how it can affect Stage III lung cancer. TRC102 will be added to the usual treatment. The addition of TRC102 to the usual treatment could stabilize your cancer and lengthen the time you can live. This study will help the us find out if this approach is better than the usual approach.
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Testing the Combination of Abemaciclib and Olaparib for Treatment of Ovarian Cancer
The purpose of this study is to learn more about using abemaciclib and olaparib to treat ovarian cancer that has returned. This study tests different doses of the drugs to find the highest dose that is safe and well tolerated. We also want to see what side effects may occur.
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Comparing Two Surgical Procedures to Reduce the Risk of Ovarian Cancer
The purpose of this study is to compare two different surgeries to reduce the risk of ovarian cancer. The study will look at the process used to decide which surgery is best for the patient. It will also look at symptoms that occur after removal of the ovaries.
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Comparing Single Dose to Multiple Doses of Radiation for Patients with Cancer that Has Spread to the Brain
The purpose of this study is to find out if there are less side effects when radiation therapy is given to small areas of brain cancer over several days compared to one day. We want to find out if this approach is better or worse than the usual approach.
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Finding Better Ways to Diagnose, Treat and Prevent Cancer in Children
The purpose of creating the database is to help find better ways to diagnose, treat and prevent cancer in children.
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Understanding How to Best Care for Patients in the Brain Tumor Clinic
This study will collect information from patients seen in the Brain Tumor Clinic at Wake Forest Baptist Comprehensive Cancer Center. The database will include the patient's symptoms, condition and response to treatment. The data will be used to understand how we can best care for patients seen in our clinic.
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