Search Studies
Finding Better Ways to Diagnose and Treat Leukemia in Children, Adolescents and Young Adults
The purpose of this study is to test bone marrow and blood from people with leukemia. We want to see if the leukemia has certain traits that could help the doctors decide what medicine might be best for you. This study will also collect information about your treatment for leukemia. We want to see how well it worked and find out if there were any long-term side effects.
Study Topics
Treating Glioblastoma with the Study Drug Dichloroacetate
The purpose of the study is to find out if the study drug, Dichloroacetate, can keep glioblastomas from growing. We want to know if the study drug can help improve the health of patients with glioblastomas that have returned or been difficult to treat.
Study Topics
Reducing Distress and Tobacco Use in Cancer Survivors with At-Home Brain Stimulation
The purpose of this study is to find out if transcranial direct current stimulation (TDCS) is easy to use at home. We also want to find out how well it works for reducing distress and decreasing cigarette use. TDCS is a form of brain stimulation. This type of stimulation is done outside of the body. The largest risk with this study is minor discomfort such as warmth, itching or tingling sensation during treatment.
Study Topics
Mental Health Substance Use (Alcohol, Illegal Drugs, Tobacco) Cancer
Finding Therapies that Improve Survival for Patients with Glioblastomas
The purpose of this research is to test multiple study treatments for glioblastoma. We want to find out if any of these study treatments can improve how long patients live.
Study Topics
Learning More About the NeuroBlate System to Treat Cancer that Has Spread to the Brain
The purpose of this study is to better understand how well the NeuroBlate System works for treating brain metastases. The system will be used along with laser interstitial thermal therapy (LITT). The NeuroBlate System uses laser light energy to heat and destroy the tumor. The LITT procedure includes a biopsy of brain tissue. The procedures are considered to be minimally invasive.
Study Topics
Treating Recurrent Grade IV Glioma with NEO100
The purpose of this study is to find out how well the study drug, NEO100, works for treating glioblastoma that has returned after treatment.
Study Topics
Comparing Stereotactic Radiosurgery to Whole Brain Radiotherapy
The purpose of this study is to find out if stereotactic radiosurgery can reduce your symptoms and lower the chance of the cancer growing or getting worse. Stereotactic radiosurgery is commonly used to treat brain tumors. It is a one or two-day outpatient procedure. A high dose of radiation is delivered to small spots in the brain not including the normal brain. We want to find out if this approach is better or worse than the usual approach for cancer that has spread to the brain.
Study Topics
Can Immunotherapy Help Non-Small Cell Lung Cancer Patients Improve Physical Function
The purpose of this study is to see if treatment with immunotherapy can help lung cancer patients who get tired easily and struggle with some daily tasks.
Study Topics
Is it More Helpful to Give Children with Germ Cell Tumors Chemotherapy on a Faster Schedule
A germ cell tumor is a type of cancer found in the ovaries for females or the testes for males. This tumor may also be found in the pelvis along the tailbone, chest, abdomen, and other structures of the body. Chemotherapy is the medicine used to fight cancer. We want to find out if giving children with germ cell tumors chemotherapy on a faster schedule is effective.
Study Topics
A study on the Effectiveness of Four Drugs (Vismodegib, GSK2256098, capivasertib, abemaciclib) Against Meningioma Tumors
The purpose of this study is to see if tumor genetic testing would be helpful when selecting a treatment for meningioma. The usual treatment for meningioma is the same for all patients and not based on tumor genetic testing. This study will look at the tissue of your tumor to see what types of mutations it has across different types of genes. Study treatment will be based on the type of altered genes in your tumor.
Study Topics
Combination Chemotherapy for Newly Diagnosed and Relapsed Wilms Tumor
The purpose of this study is to find out if we can improve treatment for those with Wilms tumors. We will be testing three different combinations of radiation and chemotherapy. The combination you receive will depend on your type of Wilms tumor.
Study Topics
Cancer Cancer: Kidney, Liver, Pancreas Children, Infants, Teen Health
Study Identifying Genetic Markers of Ovarian Cancer
The purpose of this study is to learn more about biological markers found in tissue, blood, and fluids. These markers may be able to tell us how severe a cancer can be and how well a cancer is responding to treatment.
Study Topics
I-SPY 2 TRIAL: Study of New Drugs to Treat Breast Cancer Before Surgery
The purpose of this study is to learn more about giving the best treatment at the right time. Treatment on this study will be given before surgery. This allows us to better understand how different people's breast cancers respond to commonly used chemotherapy with or without new drugs.
Study Topics
Learning More About Treating Gastric, Gastroesophageal Junction and Pancreatic Tumors with ASP2138
The purpose of this study is to find out how well the study drug, ASP2138, works for treating gastric, gastroesophageal junction or pancreatic tumors. We also want to learn more about the side effects that may be caused by the study drug.
Study Topics
Cancer Cancer: Kidney, Liver, Pancreas Cancer: Stomach and Intestines
Testing the Use of Chemo Before and After Pancreatic Cancer Surgery
We would like to find out if chemo before and after pancreatic cancer surgery will help keep the cancer away.
Study Topics
Learning More About the Benefits of Chemotherapy Before and After Surgery for Gallbladder Cancer
The usual treatment for gallbladder cancer includes chemotherapy after surgery. We want to find out if it is better to give chemotherapy both before and after surgery. We want to see if this approach is better or worse than the usual approach.
Study Topics
A Study of the Drug ABBV-383 for Patients with Multiple Myeloma
The purpose of this study is to learn more about the study drug ABBV-383 for patients with multiple myeloma that has returned or has not responded to treatment. We want to find the best dose and learn about the safety and effects of the study drug.
Study Topics
Learning More About the Study Drug GP-2250 for Treating Advanced Pancreatic Adenocarcinoma
The purpose of this study is to find out how the study drug GP-2250 may affect advanced pancreatic cancer. The study drug will be given along with the usual treatment Gemcitabine. We want to see if this combination works better than the usual approach. We also want to learn more about possible side effects.
Study Topics
Internet-Based Program to Help Cancer Survivors Manage Pain
The purpose of this study is to learn more about an internet-based pain program combined with pain education. We want to see if the pain program and education can help reduce pain and improve impact on daily activities. We also want to see if this approach is better or worse than the usual approach.
Study Topics
A Study of the Drug Durvalumab for Patients with High-Risk Liver Cancer
The purpose of this study is to learn more about the study drug Durvalumab when combined with classic chemotherapy. We want to find out if this approach is better or worse than the usual approach for your liver cancer.
Study Topics