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Studying a New Cancer Treatment for Patients with Blood Cancer
The purpose of this study is to learn more about a new treatment for patients with blood cancer. We want to see if the treatment called AZD0486 when used alone or with other cancer treatment, is safe and useful. We are looking for volunteers with a one of these types of blood cancers: mantle cell lymphoma, chronic lymphocytic leukemia, or small lymphocytic lymphoma. The study team will provide more information.
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Studying the Drug REGN5678 for Patients with Prostate Cancer
The purpose of this study is to learn more about a treatment for patients with prostate cancer. We want to see if the study drug called REGN4336 is safe and useful for patients with castration-resistant prostate cancer that has spread to other parts of the body. Study team will provide more information.
Study Topics
Studying Vitamin C Levels and Blood Cancer Treatment Outcomes
The purpose of this study is to see if vitamin C levels affect how well treatments work for people with certain types of blood cancer. We will also look at specific genes that might affect vitamin C in the body. This study will help us understand if vitamin C can improve treatment results for these cancers. We are looking for volunteers with acute myeloid leukemia, myelodysplastic syndromes, or chronic myelomonocytic leukemia.
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Studying the Medicine Triptorelin to Protect Ovaries During Chemotherapy
The purpose of this study is to learn more about a medicine called triptorelin. We want to find out if it can help protect the ovaries of teens and young adults during cancer treatment. Some cancer drugs can damage the ovaries and make it harder to have children later in life. Our researchers are studying this medicine to see if it works better than the usual methods used to protect the ovaries. We are looking for women volunteers with cancer who are receiving a specific type of chemotherapy called an alkylating agent.
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Helping Patients with Cancer Quit Smoking With New Therapy
The purpose of this study is to learn more about a kind of therapy called Dialectical Behavior Therapy Skills Training (DBT-ST). We want to see if this therapy can help people with cancer who smoke to smoke less or quit. We want to find out how it affects their feelings, stress, and how they deal with tough situations. We will also see if people with cancer who smoke would be willing to try this therapy if it were part of their regular care.
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Substance Use (Alcohol, Illegal Drugs, Tobacco) Wellness and Lifestyle Cancer
Treating Neuroendocrine Carcinoma with Atezolizumab
The purpose of this study is to see if adding the study drug, atezolizumab, to the usual cancer treatment helps people with a type of cancer that starts outside the lungs called neuroendocrine carcinoma.
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Testing the Study Drug KTX-1001 for The Treatment of Multiple Myeloma
The goal of this study is to learn more about the study drug KTX-1001. We want to find out if this drug is safe for patients with multiple myeloma that has returned or didn't respond to treatment. We also want to see if patients can handle the taking the drug.
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Testing the Study Drug INX-315 for Patients with Advanced Cancer
The purpose of this study is to learn more about the study drug INX-315. We want to see if this study drug is a safe treatment for patients with certain types of advanced cancer or cancer that has spread to other parts of the body. Study team will provide more information on eligibility criteria.
Study Topics
Stem Cell Transplant After Chemotherapy for Lymphoma Patients
The purpose of this study is to find out if giving a stem cell transplant after chemotherapy helps people with Peripheral T-cell Lymphoma stay healthy longer. Doctors will compare people who get the transplant to people who do not. The goal is to see which way works better to keep the cancer from coming back.
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Testing the Study Drug PRO1160 for Advanced Kidney, Throat, and Blood Cancers
The purpose of this study is to learn more about the new drug PRO1160. We want to see if it is safe and helpful for treating patients with cancer that didn't fully respond to treatment or has come back. Volunteers must have kidney cancer, throat cancer, or a type of blood cancer called non-Hodgkin lymphoma.
Study Topics
Cancer Cancer: Ear, Nose, Mouth, Throat Cancer: Kidney, Liver, Pancreas Cancer: Lymphoma
Testing Two Different Ways to Help Unblock Stomachs
The purpose of this study is to compare two different treatments to help people with blocked stomachs, usually because of cancer. We want to see which treatment works better and can lower the chance of symptoms like pain, nausea or vomiting from coming back.
Study Topics
Stomach and Intestines Cancer Cancer: Stomach and Intestines
Studying Plixorafenib for Cancers with BRAF Gene Changes
The purpose of this study is to learn more about the medicine plixorafenib. We want to see if this medicine can help people whose cancer has a change in the BRAF gene. The medicine is being studied to see if it works and if it is safe. People in the study will take the medicine and be watched closely for any changes or side effects.
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A Study of the Drug Reparixin for Patients with Myelofibrosis
The purpose of this study is to learn more about the study drug Reparixin. This study drug is for people with a type of blood cancer called myelofibrosis. We want to find out if Reparixin is safe and if it helps treat this cancer.
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Testing the Study Drug Levocarnitine to Prevent Liver Damage in Leukemia or Lymphoma Patients
The purpose of this study to learn more about the study drug Levocarnitine. We want to see if this study drug protects the liver from chemotherapy for leukemia or lymphoma.
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Testing the Study Drug DFP-10917 for Patients with Acute Myeloid Leukemia
The purpose of this study is to find out more about the drug DFP-10917. We want to see if it is safe and helpful for treating people with acute myeloid leukemia.
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Using the TheraBionic Device to Treat Advanced Pancreatic Cancer
The purpose of this study is to find out how the TheraBionic device will affect pancreatic cancer. The TheraBionic device is a small portable device. We want to see if the device will prevent cancer growth.
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Studying a Blood Test to Guide Cancer Treatment After Surgery
The purpose of this study is to see if a blood test can help doctors decide who needs extra cancer treatment after surgery for bladder, kidney. Ureter, or urethra cancer. The blood test looks for cancer DNA in the blood. If the test finds cancer DNA, patients may get one or two cancer drugs, or they may be watched closely.
Study Topics
Cancer Cancer: Kidney, Liver, Pancreas Cancer: Urinary and Bladder
A Study of the Drug ORIC-944 for Patients with Prostate Cancer
The purpose of this study is to learn more about the study drug ORIC-944. We want to see if this study drug is safe and useful to treat patients with prostate cancer that has spread to other areas of the body.
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Studying New Treatments for High-Risk Head and Neck Cancer
The purpose of this study is to find a new treatment for people with head and neck cancer. We want to see if using radiation therapy with two different mixes of drugs is better than the usual treatment. The first mix is radiation therapy with the drugs called docetaxel and cetuximab. The second mix is radiation therapy with the drug called cisplatin and an immunotherapy drug called atezolizumab. We are looking for volunteers who have had surgery to remove high-risk cancer in the mouth, throat, voice box, or lower throat.
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Comparing Treatments for Patients with Newly Diagnosed AML
The purpose of this study is to see how well the study drug, CPX-351 works for treating acute myeloid leukemia. We want to find out if this approach works better than the usual approach. We also want to learn more about the possible side effects of this treatment.
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