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Studying Vitamin C Levels and Blood Cancer Treatment Outcomes
The purpose of this study is to see if vitamin C levels affect how well treatments work for people with certain types of blood cancer. We will also look at specific genes that might affect vitamin C in the body. This study will help us understand if vitamin C can improve treatment results for these cancers. We are looking for volunteers with acute myeloid leukemia, myelodysplastic syndromes, or chronic myelomonocytic leukemia.
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Adding Metformin to Standard Treatment for Soft Tissue Sarcoma
The purpose of this study is to learn if adding metformin to standard cancer treatment can help people with advanced soft tissue sarcoma. Researchers want to see if this combination may improve outcomes compared to usual treatment alone. This study is for volunteers diagnosed with advanced or metastatic soft tissue sarcoma that cannot be removed with surgery.
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Using a Blood Test to Track Cervical Cancer Treatment Response
The purpose of this study is to learn more about a blood test called circulating tumor DNA (ctDNA) in people with locally advanced cervical cancer. Our researchers want to see how ctDNA levels change during and after chemotherapy and radiation treatment. The goal is to learn if this blood test can help track how well treatment is working.
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Studying a New Medicine for Multiple Myeloma
The purpose of this study is to learn about the study medicine ABBV-453. We want to see if this medicine is safe and helpful for patients with Multiple Myeloma. The study team will provide more information.
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Studying the Medicine Lisaftoclax for High-Risk Bone Marrow Blood Disorder
High risk myelodysplastic syndrome (HR-MDS) is a bone marrow blood disorder. The purpose of this study is to learn more about the medicine lisaftoclax for this disorder. Researchers want to see if lisaftoclax with standard treatment works better than standard treatment alone.
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Testing the Study Drug KTX-1001 for The Treatment of Multiple Myeloma
The goal of this study is to learn more about the study drug KTX-1001. We want to find out if this drug is safe for patients with multiple myeloma that has returned or didn't respond to treatment. We also want to see if patients can handle the taking the drug.
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Testing the Study Drug INX-315 for Patients with Advanced Cancer
The purpose of this study is to learn more about the study drug INX-315. We want to see if this study drug is a safe treatment for patients with certain types of advanced cancer or cancer that has spread to other parts of the body. Study team will provide more information on eligibility criteria.
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A Study of the Drug ORIC-944 for Patients with Prostate Cancer
The purpose of this study is to learn more about the study drug ORIC-944. We want to see if this study drug is safe and useful to treat patients with prostate cancer that has spread to other areas of the body.
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Studying the Drug SNDX-5613 for Patients with Acute Myeloid Leukemia
The study aims to learn more about the drug SNDX-5613. We want to find the best dose for patients with a blood cancer called acute myeloid leukemia. We also want to see how this drug works when used with two other drugs, daunorubicin and cytarabine.
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Studying a New Medicine for Children With JMML
The purpose of this study is to learn more about a medicine called trametinib. Researchers want to see if the medicine used with other cancer treatments, is safe and works well for children and young adults who were recently diagnosed with juvenile myelomonocytic leukemia (JMML). Researchers hope to find better treatment options for children with this rare blood cancer.
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Comparing Treatments for Patients with Newly Diagnosed AML
The purpose of this study is to see how well the study drug, CPX-351 works for treating acute myeloid leukemia. We want to find out if this approach works better than the usual approach. We also want to learn more about the possible side effects of this treatment.
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Treating Neuroblastoma in Young People with Naxitamab
The purpose of this study is to test the safety and effectiveness of adding a new drug called naxitamab to the usual treatment for a type of cancer called neuroblastoma.
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Cancer Cancer: Head, Neck Cancer: Thyroid, Other Glands Children, Infants, Teen Health
Studying New Treatments for High-Risk Multiple Myeloma
Researchers want to find out if new drug treatments work better than the usual treatment for people with high-risk multiple myeloma that was recently diagnosed. The study will compare different treatment options to learn which treatments are safest and most effective.
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Studying Inobrodib for Multiple Myeloma
The purpose of this study is to learn more about a medicine called inobrodib. Our researchers will study this medicine along with two other medicines among people with multiple myeloma. The study will look at how safe this treatment is and how well it works when other treatments have stopped working.
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Following Patients Taking Talvey for Multiple Myeloma
The purpose of this study is to learn about the experiences of people with multiple myeloma who are starting Talvey (talquetamab). Volunteers will complete surveys over one year to help researchers better understand quality of life, symptoms, and treatment experiences. This study is for people who have been prescribed Talvey but have not started treatment yet.
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Studying a Breast Cancer Medicine Given Under the Skin
The purpose of this study is to find out if the breast cancer medicine trastuzumab deruxtecan (T-DXd) is safe when given as a shot under the skin. The medicine is already used through an IV, but our researchers will study a quicker way to give it. We hope this new way will help people with advanced breast cancer.
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Studying Chemo Before Surgery for Abdominal Sarcoma
The purpose of this study is to learn more about giving chemotherapy before surgery for a type of cancer called retroperitoneal sarcoma. We want to see if this helps lower the chance of the cancer coming back. We will compare two groups: one that gets surgery only and one that gets chemotherapy first and then surgery. This will help doctors learn which treatment works better in the future.
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Learning More about Sleep Problems Among Lung Cancer Survivors
The purpose of this study is to learn more about sleep problems among patients who have had lung cancer. We want to better understand how to find and help address sleep problems by asking questions about how sleep affects patients' health and feelings. The goal is to find better ways to help our patients sleep.
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Studying the Medicine Olutasidenib for AML After Venetoclax
The purpose of this study is to learn more about the medicine olutasidenib. Researchers want to see if this medicine can help adults with a type of blood cancer called acute myeloid leukemia (AML) that has come back or has not improved after treatment with venetoclax.
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