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Learning More About Treating Advanced Non-small Cell Lung Cancer with Ramucirumab and Pembrolizumab
The purpose of this study is to find out if treating non-small cell lung cancer with the study drugs, ramucirumab and pembrolizumab, can help patients live longer. We want to find out if this approach is better than the usual approach to treating this type of lung cancer.
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Using the Study Drugs M1774 and Avelumab to Treat Merkel Cell Skin Cancer
The purpose of this study is to learn more about the study drug M1774. We want to see how well the study drug treats Merkel cell cancer when used alone and when combined with Avelumab. We want to find out if either approach is better or worse than the usual treatment.
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Testing a New Study Drug to Treat Polycythemia Vera
The purpose of this study is to test a new treatment for polycythemia vera. The study drug is called ISIS 702843. We want to find out how well the study drug works. We also want to learn more about the side effects of the study drug.
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Promoting Emotional Well-Being in Young Adult Cancer Survivors
The purpose of this study is to learn more about wellness and quality of life among young adult cancer survivors. We hope to promote well-being and teach skills to help with coping and mood management.
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Learning More About Blood Tests to Determine if a Cancer Patient Will Respond to Treatment
Not all patients treated with immune checkpoint inhibitors respond with tumor shrinkage. Many patients have serious side effects. The purpose of this study is to develop blood tests that can help determine if patients will respond to treatment and develop side effects.
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Treating Skin Lesions Caused by Colorectal Cancer Treatment
The purpose of this study is to learn more about the study drug, LUT014. We want to see how well it treats acneiform lesions.
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Testing the Addition of a New Drug, Daratumumab/rHuPH20, to the Usual Treatment for Multiple Myeloma
The purpose of this study is to see how well adding the drug, daratumumab/rHuPH20, to the usual treatment works for treating multiple myeloma. We want to find out if adding the drug could help patients live longer after stem cell transplant.
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Treating Ovarian Cancer with Luveltamab Tazevibulin
The purpose of this study is to find the best dose of the study drug, luveltamab tazevibulin, for treating ovarian cancer. We also want to learn about any side effects that may be caused by the study drug.
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Study of the Drug Inotuzumab Ozogamicin in Patients with Disseminated B-cell Lymphoblastic Lymphoma
The purpose of this study is to find out if the study drug, Inotuzumab Ozogamicin, can help treat certain types of leukemia. The study drug will be given along with the usual chemotherapy.
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Testing the anti-cancer drug erdafitinib for brain cancers
The purpose of this study is to test the good and bad effects of the study drug, erdafitinib. We want to find out if the study drug is better or worse than other treatments for brain cancer.
Study Topics
Using Dabrafenib and Trametinib After Radiation for Treating High-Grade Glioma
High-grade glioma is a type of cancer in the brain or spinal cord. The purpose of this study is to find out what effects dabrafenib and trametinib have on people with high-grade glioma.
Study Topics
Cancer Cancer: Brain, Nervous System, Spinal Cord Cancer: Children, Teens
Using Muscadine Grape Extract to Help with Fatigue Caused by Prostate Cancer Treatment
Men being treated for prostate cancer can experience fatigue. The purpose of this study is to find out if muscadine grape extract can help improve that fatigue.
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Learning More About Treating Solid Tumors with SGN-EGFRd2
The purpose of this study is to find out how well the study drug, SGN-EGFRd2, works for treating solid tumor cancers. We also want to find out what side effects may be caused by the study drug.
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Low Muscle Mass and its Role in Side Effects from Colorectal Cancer Treatment in Older Adults
The purpose of this study is to find out if low muscle mass plays a role in side effects from colorectal cancer treatment.
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Learning More About a New Approach to Treating Ductal Carcinoma In Situ
Some ductal carcinoma in situ (breast cancer) is lower risk than others for turning into invasive cancer. The purpose of this study is to try and figure out which ductal carcinoma in situ is low risk. It's possible low-risk breast cancer can be treated with only hormone therapy pills and avoid surgery.
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Are 3D Mammograms Better for Finding Life-Threatening Breast Cancer
A mammogram is an x-ray picture of the breast. The purpose of this study is to find out if 3D mammograms are better than digital mammograms at finding life-threatening breast cancer.
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Using Belumosudil to Treat Chronic Graft Versus Host Disease
The purpose of this study is to learn more about the study drug Belumosudil. We want to see how well the study drug works for treating chronic graft versus host disease. We also want to learn more about the side effects that may be caused by the study drug.
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Treatment of Acute Lymphoblastic Leukemia with Inotuzumab Ozogamicin and Blinatumomab
The purpose of this study is to find out if the study drugs, Inotuzumab Ozogamicin and Blinatumomab, can improve the chance of your leukemia going away. We also want to find out if we the study drugs can lower the chance of your leukemia coming back. We want to find out if this approach is better or worse than the usual approach.
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Medical Problems After Treatment for Childhood Cancer
One goal of this study is to look at how other medical problems develop after treatment for childhood cancer. We want to see how these problems relate to the type of cancer, stage of cancer and treatment. We also want to compare cancer patients with these problems to other cancer patients with the same diagnosis who do not have problems after treatment.
Study Topics
Treating B-Acute Lymphoblastic Leukemia (B-ALL) in Children and Young Adults with Inotuzumab Ozogamicin
Lymphoblastic Leukemia (B-ALL) is a cancer of the white blood cells. The purpose of this study is to find out how well the study drug, Inotuzumab ozogamicin, works for children and young adults with B-ALL.
Study Topics