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Testing Cardiac Rehab for Amyloidosis
The study aims to find out if exercise programs can help people with this condition feel better.
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Heart Device Safety and Medication Study
The purpose of this study is to learn more about a device to help patients with a heart condition called atrial fibrillation. We want to see how safe and useful different medications are after the device called WATCHMAN FLX Pro is placed in the heart. This device helps prevent blood clots and strokes in patients with atrial fibrillation.
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Testing the Study Drug Bromocriptine for New Moms with Heart Problems
Peripartum cardiomyopathy is when your heart gets weak and big during or after pregnancy. This makes it hard for your heart to pump blood like it should. The study is testing a drug called bromocriptine to help women with this problem.
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Studying the Drug MT-7117 for Patients with a Rare Blood Disorder
The purpose of this study is to learn more about the study drug MT-7117. We want to see if this study drug is useful for patients with a rare blood disorder called Erythropoietic Protoporphyria. We also want to see if this study drug is tolerable to take.
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Studying the Drug Plozasiran for Patients with Severe Hypertriglyceridemia
Hypertriglyceridemia is when you have too much fat in your blood. This study wants to see if the drug plozasiran is safe and works well to lower this fat in people with severe hypertriglyceridemia.
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Testing the Study Drug Plozasiran for People with Hypertriglyceridemia
Hypertriglyceridemia is a condition where you have a high level of fat in your blood. The purpose of this study is to learn more about the study drug plozasiran for this condition. We want to find out if this study drug is safe and if it can help lower the fat levels in your blood.
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Preventing Heart Disease in Psoriasis Patients
The purpose of this study is to test a new care program to help people with psoriasis lower their risk of heart disease. Examples of health risks are high cholesterol, high blood pressure, diabetes, and smoking that can lead to heart attacks or strokes. We want to see if a care coordinator can help patients manage their heart health better.
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Testing the Study Drug Inclisiran for Lowering Bad Cholesterol in Patients with Heart Disease
The purpose of this study is to learn more about the study drug Inclisiran. We want to see if this study drug is safe and useful for lowering bad cholesterol in patients with heart disease. We will compare using this study drug with usual care versus usual care alone.
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Learning More About the Treatment of Bleeding, Clotting or Non-neoplastic Blood Disorder
The main purpose of this study is to look at the how well the treatments for non-neoplastic blood disorders work. We also want to look at the side effects that may be caused by the treatments.
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Collecting Data from Hemophilia Patients
The purpose of this study is to collect data on a blood disorder called hemophilia. The data will be used to improve the care of patients.
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Heart Health Cancer Cancer: Children, Teens Children, Infants, Teen Health
Can Physical Activity Be Helpful for Lymphoma Patients During Treatment?
The purpose of this study is to find out if exercise or educational classes can be helpful for lymphoma patients. We want to know if exercise or classes can help patients keep their quality of life and ability to exercise. We also want to know if exercise or classes can help lymphoma patients with memory and heart health.
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Learning More About the Effects of Very Low-Nicotine Cigarettes on the Heart
The purpose of this study is to learn more about the effects of very low-nicotine cigarettes on the heart.
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Heart Health Substance Use (Alcohol, Illegal Drugs, Tobacco)
Finding Out if Inclisiran Can Help Prevent Heart-Related Events Like Heart Attack or Stroke
The purpose of the study is to find out if the study drug, inclisiran, can prevent heart-related events by lowering LDL-cholesterol in the blood. LDL cholesterol is also known as bad cholesterol.
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Looking Into the Need of Blood Thinners as Treatment for Atrial Fibrillation
Blood thinning drugs are usually used to treat atrial fibrillation. Atrial fibrillation is when the heart has an irregular and often very fast heart rhythm. Blood thinners lower the risk of stroke but also increase the risk of bleeding. It may not be necessary for people who have short or infrequent atrial fibrillation to take blood thinners. The purpose of this study is to find out if it is safe to stop blood-thinning medication during long periods of normal heart rhythm.
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Studying Causes of Heart Failure
This purpose of this study is to understand what causes heart failure. Some people with early-stage heart failure might not know they have it because they feel fine, while others may have many or few symptoms. We want to learn why some people get heart failure and how to better classify it for targeted treatments. We are recruiting volunteers with and without heart failure to learn more.
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High Blood Pressure in Children and Teenagers
The purpose of this study is to understand what causes high blood pressure in young people. We also want to learn more about how high blood pressure can cause damage to the heart and kidneys.
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Healthy Volunteers Heart Health Children, Infants, Teen Health
Studying the Drug Metformin for Older Patients with Heart Failure
This study wants to see if the medicine Metformin XR can help older people with this heart problem. We also want to learn about the side effects and see if it can make their health better.
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Study of Bempedoic Acid for Treating High Cholesterol in Children
Heterozygous familial hypercholesterolemia (HeFH) is an inherited genetic disorder. It causes dangerously high cholesterol levels. This study will see if bempedoic acid works at lowering cholesterol in kids with HeFH. Bempedoic has been tested in adults, but it has not been tested in children or young adults yet.
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How Salt Affects Blood Pressure in Young Adults Who Were Born Prematurely
The purpose of this study is to learn about how salt in the diet affects blood pressure in young adults who were born prematurely. We also want to find out if the medication, allopurinol, can change how salt in the diet affects blood pressure.
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Healthy Volunteers Heart Health Kidneys, Liver, Pancreas Children, Infants, Teen Health
Study of MK-0616 for Reducing Major Heart-Related Events
The purpose of this study is to test a drug called MK-0616. It will be tested in adults at high risk for a major heart related event. Examples of major heart-related events include heart attack and stroke. We want to find out how well MK-0616 reduces the risk of major heart-related events. We also want to see how MK-0616 affects cholesterol and other blood tests related to heart health.
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