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Testing the Study Device Impella for Patients with Severe Heart Disease
The purpose of this study is to learn more about the study device called Impella. We want to see if this device can be used during a high-risk heart procedure in patients with weak heart function on the left side. We want to learn if this device will improve symptoms and heart function after the procedure when compared to the standard of care treatment.
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High Blood Pressure in Children and Teenagers
The purpose of this study is to understand what causes high blood pressure in young people. We also want to learn more about how high blood pressure can cause damage to the heart and kidneys.
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Healthy Volunteers Heart Health Children, Infants, Teen Health
Testing a New Study Device for Mitral Valve Regurgitation
The purpose of this study is to test a study device called the CardioMech Mitral Valve Repair System for patients with this condition. We want to learn about the safety and effectiveness of this device.
Study Topics
Studying the Drug Metformin for Older Patients with Heart Failure
This study wants to see if the medicine Metformin XR can help older people with this heart problem. We also want to learn about the side effects and see if it can make their health better.
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Studying a Mobile App for Heart Rehab Post-Valve Procedure
The purpose of this study is to find out if an at home mobile app can help improve heart health. The app is a heart rehab program and involves a health exercise program. Volunteers in the study will be put into one of three groups: no app, using the app for 12 weeks, or using the app for 24 weeks. We are looking for volunteers who have recently had, or will soon have, a heart valve procedure to fix their aortic, mitral, or tricuspid valve.
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Testing a New Study Device for Patients with Heart Failure
The purpose of this study is to test a new study device called the CCM-D System. We want to see if this device is safe and effective for patients with heart failure and a heart that is not pumping out as much blood as it should with each beat.
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Study of Bempedoic Acid for Treating High Cholesterol in Children
Heterozygous familial hypercholesterolemia (HeFH) is an inherited genetic disorder. It causes dangerously high cholesterol levels. This study will see if bempedoic acid works at lowering cholesterol in kids with HeFH. Bempedoic has been tested in adults, but it has not been tested in children or young adults yet.
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Testing a New Heart Device for Stroke Prevention
The purpose of this study is to test a new heart device called the Laminar System. We want to see if this device is safe and works well for people with a heart condition called non-valvular atrial fibrillation. The study will help doctors understand if this device can prevent strokes in these patients.
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Testing a New Heart Valve for Mitral Regurgitation
The purpose of this study is to test a new device called the AltaValve System. We want to see if it can help treat leaky heart valves. We want to find out if the device is safe and works well for people who cannot have open-heart surgery. The study is for adults with mitral valve regurgitation.
Study Topics
Studying Diabetes Medicine for Heart and Kidney Health
The purpose of this study is to learn more about two types of diabetes medicines. We want to see which medicine type helps lower the risk of heart and kidney problems. We are looking for volunteers with type 2 diabetes and a history of heart disease or have high risk for heart disease that are patients of Elizabeth Internal Medicine and Carmel Family Physicians.
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Learning More About the Neuroguard IEP Direct System for Treatment of Carotid Artery Narrowing
The purpose of this study is to learn more about a new study device called the Neuroguard IEP Direct System to treat patients with narrowed arteries in their neck that supply blood to their brain. The treatment involves making a small cut on one side of your neck to place the device.
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Testing a New Study Device for Mitral Valve Dysfunction
The purpose of this study is to test a new study device called the Cephea Mitral Valve System for the treatment of this condition. We want to learn more about the safety and effectiveness of this device.
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Testing Cardiac Rehab for Amyloidosis
The study aims to find out if exercise programs can help people with this condition feel better.
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How Salt Affects Blood Pressure in Young Adults Who Were Born Prematurely
The purpose of this study is to learn about how salt in the diet affects blood pressure in young adults who were born prematurely. We also want to find out if the medication, allopurinol, can change how salt in the diet affects blood pressure.
Study Topics
Healthy Volunteers Heart Health Kidneys, Liver, Pancreas Children, Infants, Teen Health
Study of MK-0616 for Reducing Major Heart-Related Events
The purpose of this study is to test a drug called MK-0616. It will be tested in adults at high risk for a major heart related event. Examples of major heart-related events include heart attack and stroke. We want to find out how well MK-0616 reduces the risk of major heart-related events. We also want to see how MK-0616 affects cholesterol and other blood tests related to heart health.
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Heart Device Safety and Medication Study
The purpose of this study is to learn more about a device to help patients with a heart condition called atrial fibrillation. We want to see how safe and useful different medications are after the device called WATCHMAN FLX Pro is placed in the heart. This device helps prevent blood clots and strokes in patients with atrial fibrillation.
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Learning More about the Study Drug Lepodisiran to Reduce Heart Attacks and Stroke
The purpose of this study is to learn more about the study drug lepodisiran. We want to see if the study drug can reduce problems like heart attack or stroke in adults with elevated lipoprotein (a). We also want to learn more about the side effects that may be caused by the study drug.
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Using Body Fat Images to Assess Health
The purpose of this study is to see if we can use medical images of fat throughout the body to assess your health status.
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Testing the Study Drug Pelacarsen to Slow Calcium Build-Up in the Heart Valve
The purpose of this study to learn more about the study drug pelacarsen for patients with calcific aortic valve stenosis. We want to see if the study drug can help safely slow the progression of calcium build-up on the heart valve. Calcium build-up causes narrowing and restricting of blood flow from the heart to the rest of the body.
Study Topics