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Studying Vitamin C Levels and Blood Cancer Treatment Outcomes
The purpose of this study is to see if vitamin C levels affect how well treatments work for people with certain types of blood cancer. We will also look at specific genes that might affect vitamin C in the body. This study will help us understand if vitamin C can improve treatment results for these cancers. We are looking for volunteers with acute myeloid leukemia, myelodysplastic syndromes, or chronic myelomonocytic leukemia.
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Studying a New Medicine for Children With JMML
The purpose of this study is to learn more about a medicine called trametinib. Researchers want to see if the medicine used with other cancer treatments, is safe and works well for children and young adults who were recently diagnosed with juvenile myelomonocytic leukemia (JMML). Researchers hope to find better treatment options for children with this rare blood cancer.
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Comparing Treatments for Patients with Newly Diagnosed AML
The purpose of this study is to see how well the study drug, CPX-351 works for treating acute myeloid leukemia. We want to find out if this approach works better than the usual approach. We also want to learn more about the possible side effects of this treatment.
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Studying the Medicine Olutasidenib for AML After Venetoclax
The purpose of this study is to learn more about the medicine olutasidenib. Researchers want to see if this medicine can help adults with a type of blood cancer called acute myeloid leukemia (AML) that has come back or has not improved after treatment with venetoclax.
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Studying a New Blood Test for Patients with Blood Cancer
The purpose of this study is to create a new blood test for patients with blood cancer. We want to see if this new blood test can help predict which patients will benefit from a type of immunotherapy called CAR T-cell therapy. We are looking for volunteers with blood cancer that are eligible to receive CAR T-cell therapy. The study team will provide more information.
Study Topics
Cancer Cancer: Blood Cancer: Leukemia Cancer: Lymphoma Cancer: Myeloma
Studying Two Medicine Combinations for Chronic Lymphocytic Leukemia
The purpose of this study is to compare the combination of sonrotoclax and zanubrutinib against the combination of venetoclax and acalabrutinib. Researchers want to learn which combination works better and is safe for treating chronic lymphocytic leukemia (CLL).
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Comparing a New Treatment For Blood Cancer Patients
The purpose of this study is to learn about a new treatment called Inotuzumab Ozogamicin. We want to see if it helps people with blood cancer. We will compare the results of patients who get this new treatment with those who get the usual treatment. We are looking for volunteers who are newly diagnosed with one of these blood cancers: high-risk B-cell acute lymphoblastic leukemia (B-ALL), mixed-phenotype acute leukemia (MPAL), or disseminated B lymphoblastic lymphoma (B-LLy).
Study Topics
Cancer Cancer: Blood Cancer: Children, Teens Cancer: Leukemia
Improving Cancer Care for Young Patients
The purpose of this study to find better ways to diagnose, treat, and prevent cancers in children, teenagers, and young adults. Our goal is to gather information about cancer treatments and their results to improve future care. We are looking for volunteers who have cancer or other conditions where cells grow abnormally. The study team will provide more details.
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